A synthetic double-stranded RNA, poly I: C, induces a rapid apoptosis of human CD34+ cells

Experimental Hematology

Volumn 40, Issue 4, 2012, Pages 330-341

  Liu, Jiajia ^a   Guo, Yong Mei ^a   Hirokawa, Makoto ^b   Iwamoto, Keiko ^a   Ubukawa, Kumi ^a   Michishita, Yoshihiro ^a   Fujishima, Naohito ^b   Tagawa, Hiroyuki ^a   Takahashi, Naoto ^a   Xiao, Weiguo ^c   Yamashita, Junsuke ^a   Ohteki, Toshiaki ^d,e   Sawada, Kenichi ^a  

^a AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b AKITA UNIVERSITY HOSPITAL   (Japan)

^c CHINA MEDICAL UNIVERSITY   (China)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; CD34 ANTIGEN; DOUBLE STRANDED RNA; HELICASE; INTERFERON RECEPTOR; MELANOMA DIFFERENTIATION ASSOCIATED ANTIGEN 5; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN NOXA; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMATOLOGIC DISEASE; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASES; CELL LINEAGE; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DEAD-BOX RNA HELICASES; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; INTERFERON-ALPHA; INTERFERON-BETA; MOLECULAR WEIGHT; OLIGODEOXYRIBONUCLEOTIDES; OLIGOPEPTIDES; POLY A-U; POLY I-C; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, INTERFERON; RNA, MESSENGER; TOLL-LIKE RECEPTOR 3; UP-REGULATION;

DSRNA VIRUSES; RNA VIRUSES;

EID: 84862831148     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2011.12.002     Document Type: Article

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