Dual β2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1523-1526

  Shan, Wen Jun ^a   Huang, Ling ^a   Zhou, Qi ^a   Jiang, Huai Lei ^a   Luo, Zong Hua ^a   Lai, Ke Fang ^b   Li, Xing Shu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Asthma and COPD; Bronchodilator; PDE4 inhibitor

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CILOMILAST; FORMOTEROL; INDACATEROL; ISOPRENALINE; N (3,5 DICHLORO 4 PYRIDYL) [1 (4 FLUOROBENZYL) 5 HYDROXY 3 INDOLYL]GLYOXYLIC ACID AMIDE; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; ROFLUMILAST; ROLIPRAM; SALBUTAMOL; SALMETEROL;

ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; DOSE RESPONSE; DRUG DESIGN; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; DRUG TARGETING; IC 50; IN VITRO STUDY; NONHUMAN; PHARMACODYNAMICS; STRUCTURE ACTIVITY RELATION;

EID: 84862830105     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.01.013     Document Type: Article

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