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Volumn 49, Issue 8, 2001, Pages 1009-1017

Synthesis and structure - Activity relationship of N-arylrolipram derivatives as inhibitors of PDE4 isozymes

(6) Keller, Thomas H a Bray French, Katharine a Demnitz, F W Joachim a,b Müller, Thomas a Pombo Villar, Esteban a Walker, Christoph a

a Novartis Institutes for BioMedical Research (United Kingdom)

b FEDERAL UNIVERSITY OF PERNAMBUCO (Brazil)

Author keywords

N arylrolipram derivative; PDE inhibition; Rolipram; Rolipram binding

Indexed keywords

5 [4 (3 CYCLOPENTYLOXY 4 METHOXYPHENYL) 2 OXO PYRROLIDIN 1 YL] 3 (3 METHOXYBENZYLOXY)BENZOIC ACID N',N'DIMETHYLHYDRAZIDE; N PHENYLROLIPRAM; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION; EOSINOPHIL; NONHUMAN; OXIDATIVE STRESS; RAT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 0034898254 PISSN: 00092363 EISSN: None Source Type: Journal
DOI: 10.1248/cpb.49.1009 Document Type: Article

Times cited : (13)

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