Enantioselective drug-protein interaction between mexiletine and plasma protein

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 6, 2012, Pages 792-801

  Yu, Lushan ^a   Hong, Yanjun ^a   Li, Li ^a   Jin, Yingxiu ^a   Zheng, Mingyue ^b   Jiang, Hualiang ^b   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

1 acid glycoprotein; enantioselectivity; human serum albumin; mexiletine; molecular dynamics

Indexed keywords

ARGININE; LEUCINE; MEXILETINE; OROSOMUCOID; PHENYLALANINE; SERINE; SERUM ALBUMIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG INTERACTION; DRUG PROTEIN BINDING; ENANTIOSELECTIVITY; ENERGY; MATHEMATICAL ANALYSIS; MOLECULAR DYNAMICS; PLASMA;

AMINO ACIDS; BLOOD PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MEXILETINE; OROSOMUCOID; PROTEIN BINDING; SERUM ALBUMIN; STEREOISOMERISM;

EID: 84862826304     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01487.x     Document Type: Article

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