Ras/ERK1 pathway regulation of p27KIP1-mediated G1-phase cell-cycle arrest in cordycepin-induced inhibition of the proliferation of vascular smooth muscle cells

European Journal of Pharmacology

Volumn 681, Issue 1-3, 2012, Pages 15-22

  Jung, Su Mi ^a,c   Park, Sung Soo ^b   Kim, Wun Jae ^c   Moon, Sung Kwon ^a,c  

^a Chungju National University   (South Korea)

^b Cheju Halla University   (South Korea)

^c Chungbuk National University College of Medicine   (South Korea)

Author keywords

Cordycepin; G1 phase cell cycle arrest; p27KIP1; Ras ERK1; Vascular smooth muscle cell

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CORDYCEPIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RAS PROTEIN; SMALL INTERFERING RNA; THYMIDINE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MUTATOR GENE; NONHUMAN; NUCLEIC ACID TRANSPORT; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL PROLIFERATION; CORDYCEPS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DEOXYADENOSINES; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RAS PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION;

EID: 84862822807     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.02.003     Document Type: Article

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