Microtubule interaction site of the kinesin motor

Cell

Volumn 90, Issue 2, 1997, Pages 207-216

  Woehlke, Günther ^a   Ruby, Aaron K ^a   Hart, Cynthia L ^a   Ly, Bernice ^a   Hom Booher, Nora ^a   Vale, Ronald D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN; MYOSIN;

ARTICLE; BINDING SITE; MICROTUBULE; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

EID: 0030755709     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80329-3     Document Type: Article

References (56)

1. Amos, L.A., and Hirose, K. (1997). The structure of microtubulemotor complexes. Curr. Opin. Cell Biol. 9, 4-11.
2. Arnal, I., Metoz, F., DeBonis, S., and Wade, R.H. (1996). Threedimensional structure of functional motor proteins on microtubules. Curr. Biol. 6, 1265-1270.
3. Block, S.M., Goldstein, L.S., and Schnapp, B.J. (1990). Bead movement by single kinesin molecules with optical tweezers. Nature 348, 348-352.
4. Bloom, G., and Endow, S. (1995). Motor proteins 1 : kinesin. Protein Profile 1, 1112-1138.
5. Crevel, I.M.-T.C., Lockhart, A., and Cross, R.A. (1996). Weak and strong states of kinesin and ncd. J. Mol. Biol. 257, 66-76.
6. Cunningham, B.C., and Wells, J.A. (1989). High-resolution epitope mapping of the hGH-receptor interactions by alanine-scanning mutagenesis. Science 244, 1081-1085.
7. dos Remedies, C.G., and Moens, P.D. (1995).Actin and the actomyosin interface: a review. Biochim. Biophys. Acta 1228, 99-124.
8. Fisher, A.J., Smith, C.A., Thoden, J.B., Smith, R., Sutoh, K., Holden, H.M., and Rayment, I. (1995). X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AIF4-. Biochemistry 34, 8960-8972.
9. Geladopoulos, T.P., Sotiroudis, T.G., and Evangelopoulos, A.E. (1991). A malachite green colorimetric assay for protein phosphatase activity. Anal. Biochem. 192, 112-116.
10. Gilbert, S.P., and Johnson, K.A. (1993). Expression, purification, and characterization of the Drosophila kinesin motor domain produced in Escherichia coli. Biochemistry 32, 4677-4684.
11. Gilbert, S.P., Webb, M.R., Brune, M., and Johnson, K.A. (1995). Pathway of processive ATP hydrolysis by kinesin. Nature 373, 671-676.
12. Goldstein, L.S. (1993). With apologies to Scheherazade:tails of 1001 kinesin motors. Annu. Rev. Genet. 27, 319-351.
13. Hackney, D.D. (1988). Kinesin ATPase: rate-limiting ADP release. Proc. Natl. Acad. Sci. USA 85, 6314-6318.
14. Hackney, D.D. (1994). Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis. Proc. Natl. Acad. Sci. USA 91, 6865-6869.
15. Hackney, D.D. (1996). The kinetic cycles of myosin, kinesin, and dynein. Annu. Rev. Physiol. 58, 731-750.
16. Hirokawa, N. (1996). Organelle transport along microtubules-the role of KIFs. Trends Cell Biol. 6, 135-141.
17. Hirose, K., Lockhart, A., Cross, R.A., and Amos, L.A. (1995). Nucleotide-dependent angular change in kinesin motor domain bound to tubulin. Nature 376, 277-279.
18. Howard, J., Hudspeth, A.J., and Vale, R.D. (1989). Movement of microtubules by single kinesin molecules. Nature 342, 154-158.
19. Hoyt, M.A., He, L, Totis, L, and Saunders, W.S. (1993). Loss of function of Saccharomyces cerevisiae kinesin-related cin8 and kip 1 is suppressed by KAR3 motor domain mutations. Genetics 135, 35-44.
20. Huang, T.-G., and Hackney, D.D. (1993). Drosophila kinesin minimal motor domain expressed in Escherichia coli: purification and kinetic characterization. J. Biol. Chem. 269, 16493-16501.
21. Hyman, A., Dreschel, D., Kellogg, D., Salser, S., Sawin, K., Steffen, P., Wordeman, L., and Mitchison, T. (1990). Preparation of modified tubulins. Meth. Enzymol. 196, 303-319.
22. Kawashima, T., Berthet-Colominas, C., Wulff, M., Cusack, S., and Leberman, R. (1996). The structure of the Escherichia coli EF-Tu-EF-Ts complex at 2.5 Å resolution. Nature 379, 511-518.
23. Kraulis, P.J. (1991). MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J. Appl. Cryst. 24, 946-950.
24. Kull, F.J., Sablin, E.P., Lau, R., Fletterick, R.J., and Vale, R.D. (1996). Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature 380, 550-555.
25. Lambright, D.G., Sondek, J., Bohm, A., Skiba, N.K., Hamm, H.E., and Sigler, P.B. (1996). The 2.0 Å crystal structure of a heterotrimeric G protein. Nature 379, 311-319.
26. Ma, Y.Z., and Taylor, E.W. (1995). Mechanism of microtubule kinesin ATPase. Biochemistry 34, 13242-13251.
27. Ma, Y.Z., and Taylor, E.W. (1997). Interacting head mechanism of microtubule-kinesin ATPase. J. Biol. Chem. 272, 724-730.
28. Matthews, B.W. (1996). Structural and genetic analysis of the folding and function of T4 lysozyme. FASEB J. 10, 35-41.
29. McDonald, H.B., Stewart, R.J., and Goldstein, L.S. (1990). The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor. Cell 63, 1159-1165.
30. Meritt, E.A., and Murphy, M.E.P. (1994). Raster3D version 2.0: a program for photorealistic molecular graphics. Acta Cryst. D50, 869-873.
31. Milburn, M.V., Tong, L, deVos, A.M., Brunger, A., Yamaizumi, Z., Nishimura, S., Kim, S.-H. (1990). Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins. Science 247, 939-945.
32. Moore, J.D., Song, H., and Endow, S.A. (1996). A point mutation in the microtubule binding region of the Ncd motor protein reduces motor velocity. EMBO J. 15, 3306-3314.
33. Mooseker, M.S., and Cheney, R.E. (1995). Unconventional myosin. Annu. Rev. Cell Biol. 11, 633-675.
34. Nangaku, M., Sato-Yoshitake, R., Okada, Y., Noda, Y., Takemura, R., Yamazaki, H., and Hirokawa, N. (1994). KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell 79, 1209-1220.
35. Okada, Y., Yamazaki, H., Sekine-Aizawa, Y., and Hirokawa, N. (1995). The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell 81, 769-780.
36. Pearce, K.H., Ultsch, M .H., Kelley, R.F., de Vos, A.M., and Wells, J.A. (1996). Structural and mutational analysis of affinity-inert contact residues at the growth hormone-receptor interface. Biochemistry 35, 10300-10307.
37. Rayment, I., Holden, H.M., Whittaker, M., Yohn, C.B., Lorenz, M., Holmes, K.C., and Milligan, R.A. (1993a). Structure of the actinmyosin complex and its implications for musclecontraction. Science 261, 58-65.
38. Rayment, I., Rypniewski, W., Schmidt-Base, K.,Smith,R.,Tomchick, D., Benning, M.M., Winkelmann, D.A., Wesenberg, G., and Holden, H.M. (1993b). The three-dimensional structure of myosin subfragment-1: a molecular motor. Science 261, 50-58.
39. Romberg, L., and Vale, R.D. (1993). Chemomechanical cycle of kinesin differs from that of myosin. Nature 361, 168-170.
40. Rosenfeld, S.S., Rener, B., Correia, J.J., Mayo, M.S., and Cheung, H.C. (1996). Equilibrium studies of kinesin-nucleotide intermediates. J. Biol. Chem. 271, 9473-9482.
41. Sablin, E.P., Kull, F.J., Cooke, R., Vale, R.D., and Fletterick, R.J. (1996). Crystal structure of the motor domain of the kinesin-related motor ncd. Nature 380, 555-559.
42. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd Ed. (Cold Spring Harbor: Cold Spring Harbor Laboratory Press).
43. Smith, C.A., and Rayment, I. (1996). Active site comparisons highlight structural similarities between myosin and other P-loop proteins. Biophys. J. 70, 1590-1602.
44. Sosa, H., Dias, P., Hoenger, A., Whittaker, M., Wilson-Kubalek, E., Sablin, E., Fletterick, R.J., Vale, R.D., and Milligan, R.A. (1997). A model for the microtubule-ncd motor protein complex obtained by cryo-electron microscopy and image analysis. Cell, this issue, 90, 217-224.
45. Spudich, J.A. (1994). How molecular motors work. Nature 372, 515-518.
46. Svoboda, K., Schmidt, C.F., Schnapp, B.J., and Block, S.M. (1993). Direct observation of kinesin stepping by optical trapping interferometry. Nature 365, 721-727.
47. Tucker, C., and Goldstein, L.S.B. (1997). Probing the kinesin-microtubule interaction. J. Biol. Chem. 272, 9481-9488.
48. Uyeda, T.Q., Ruppel, K.M., and Spudich, J.A. (1994). Enzymatic activities correlate with chimaeric substitutions at the actin-binding face of myosin. Nature 368, 567-569.
49. Vale, R.D. (1996). Switches, latches, and amplifiers: common themes of molecular motors and G proteins. J. Cell Biol. 135, 291-302.
50. Vale, R.D., and Fletterick, R.J. (1997) The design plan of kinesin motors. Annu. Rev. Cell Biol., in press.
51. Vale, R.D., Funatsu, T., Pierce, D.W., Romberg, L., Harada, Y., and Yanagida, T. (1996). Direct observation of single kinesin molecules moving along microtubules. Nature 350,451-453.
52. Walker, R.A., Salmon, E.D.,and Endow, S.A. (1990). The Drosophila claret segregation protein is a minus-end directed motor molecule. Nature 347, 780-782.
53. Wall, M.A., Coleman, D.E., Lee, E., Iniguez-Lluhl, J.A., Posner, B.A., Gilman, A.G., and Sprang, S.R.(1995). The structure of the G protein heterotrimer. Cell 83, 1047-1058.
54. Wells, J.A. (1996). Binding in the growth hormone receptor complex. Proc. Natl. Acad. Sci. USA 93, 1-6.
55. Yang, J.T., Laymon, R.A., and Goldstein, L.S. (1989). A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell 56, 879-889.
56. Yang, J.T., Saxton, W.M., Stewart, R.J., Raff, E.G., and Goldstein, L.S. (1990). Evidence that the head of kinesin is sufficient for force generation and motility in vitro. Science 249, 42-47.