Ginsenoside Rh1 suppresses matrix metalloproteinase-1 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathway in human hepatocellular carcinoma cells

European Journal of Pharmacology

Volumn 679, Issue 1-3, 2012, Pages 24-33

  Yoon, Ji Hae ^a   Choi, Yeo Jin ^a   Lee, Seong Gene ^a  

^a Chonnam National University   (South Korea)

Author keywords

Anti metastasis; AP 1; Ginsenoside Rh1; Invasion; Migration; MMP 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTINEOPLASTIC AGENT; GINSENOSIDE RH1; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENTIATION; DRUG SYNTHESIS; ENZYME INACTIVATION; ENZYME REPRESSION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

ANTHRACENES; CELL MOVEMENT; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; FLAVONOIDS; GINSENOSIDES; HEP G2 CELLS; HUMANS; MATRIX METALLOPROTEINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TRANSCRIPTION FACTOR AP-1;

EID: 84862814611     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.01.020     Document Type: Article

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