Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism

FEBS Letters

Volumn 586, Issue 4, 2012, Pages 448-454

  Li, Jie ^a   Shiraki, Takuma ^a,b   Igarashi, Kazuhiko ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KINKI UNIVERSITY   (Japan)

Author keywords

Chromosome alignment; Leptomycin B; Nucleocytoplasmic transport; Oxidative stress

Indexed keywords

BACH1 PROTEIN; EXPORTIN 1; LEPTOMYCIN B; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN; CHROMOSOME; CONTROLLED STUDY; CYTOPLASM; DNA BINDING; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CHROMOSOME PAIRING; DNA PRIMERS; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; FATTY ACIDS, UNSATURATED; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; KARYOPHERINS; MICE; MITOSIS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PYRIMIDINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, AMINO ACID; THIONES; TRANSCRIPTION, GENETIC;

EID: 84862810861     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.01.028     Document Type: Article

References (16)

1. T.M. Kensler Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway Annu. Rev. Pharmacol. Toxicol. 47 2007 89 116
2. H. Motohashi, and M. Yamamoto Nrf2-Keap1 defines a physiologically important stress response mechanism Trends Mol. Med. 10 2004 549 557 (Pubitemid 39433824)
3. K. Igarashi, and J. Sun The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation Antioxid. Redox Signal. 8 2006 107 118 (Pubitemid 43324536)
4. H. Suzuki Cadmium induces nuclear export of Bach1, a transcriptional repressor of heme oxygenase-1 gene J. Biochem. 278 2003 49246 49253
5. J.W. Kaspar, and A.K. Jaiswal Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression J. Biol. Chem. 285 2010 153 162
6. C. Yamasaki Dynamic cytoplasmic anchoring of the transcription factor Bach1 by intracellular hyaluronic acid binding protein IHABP J. Biochem. 137 2005 287 296 (Pubitemid 40628434)
7. H. Suzuki Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1 EMBO J. 23 2004 2544 2553 (Pubitemid 38988226)
8. R. Rizkallah The transcription factor YY1 Is a substrate for polo-like kinase 1 at the G2/M transition of the cell cycle PLoS ONE 6 2011 e15928
9. Y. Kim Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E Cell 142 2010 444 455
10. J.R. Hutchin Systematic analysis of human protein complexes identifies chromosome segregation protein Science 328 2010 593 599
11. N. Tokai-Nishizumi The chromokinesin Kid is required for maintenance of proper metaphase spindle size Mol. Biol. Cell 16 2005 5455 5463 (Pubitemid 41566853)
12. A. Santamaria The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle Curr. Biol. 20 2008 723 729
13. T.U. Mayer Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen Science 286 1999 971 974
14. C.E. Walczak Mechanisms of chromosome behavior during mitosis Nat. Rev. Mol. Cell. Biol. 11 2010 91 102
15. B. Neumann Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes Nature 464 2010 720 727
16. M.J. Wood Structural basis for redox regulation of Yap1 transcription factor localization Nature 430 2004 917 921 (Pubitemid 39119222)