Regulation of the differentiation of mesenchymal stem cells in vitro and osteogenesis in vivo by microenvironmental modification of titanium alloy surfaces

Biomaterials

Volumn 33, Issue 13, 2012, Pages 3515-3528

  Hu, Yan ^a   Cai, Kaiyong ^a   Luo, Zhong ^a   Zhang, Yuan ^b   Li, Liqi ^b   Lai, Min ^a   Hou, Yanhua ^a   Huang, Yuran ^a   Li, Jinghua ^a   Ding, Xingwei ^a   Zhang, Bin ^a   Paul Sung, K L ^a  

^a CHONGQING UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

BMP2; Extracellular microenvironment; Layer by layer assembly technique; Mesenchymal stem cells; Osteogenesis; Ti6Al4V alloy

Indexed keywords

BMP2; EXTRACELLULAR; LAYER-BY-LAYER ASSEMBLY TECHNIQUE; MESENCHYMAL STEM CELL; OSTEOGENESIS; TI-6AL-4V ALLOY;

BONE; COMPUTERIZED TOMOGRAPHY; CONFOCAL MICROSCOPY; CONTACT ANGLE; ENZYME ACTIVITY; FIELD EMISSION MICROSCOPES; MULTILAYERS; PHOSPHATASES; TRANSCRIPTION FACTORS;

CELL CULTURE;

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CHITOSAN; COLLAGEN TYPE 1; FIBRONECTIN; GELATIN; OSTEOCALCIN; OSTEOPONTIN; TITANIUM; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE DEVELOPMENT; BONE MINERALIZATION; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONTACT ANGLE; CONTROLLED STUDY; ENZYME SYNTHESIS; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; GENE EXPRESSION; IMPLANT; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; MICROENVIRONMENT; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

ALKALINE PHOSPHATASE; ANIMALS; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 2; CELL ADHESION; CELL DIFFERENTIATION; CELL SHAPE; CELLULAR MICROENVIRONMENT; COATED MATERIALS, BIOCOMPATIBLE; GENE EXPRESSION REGULATION; HUMANS; IMPLANTS, EXPERIMENTAL; MESENCHYMAL STEM CELLS; MICE; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; OSTEOCLASTS; OSTEOGENESIS; RABBITS; RATS; RNA, MESSENGER; SURFACE PROPERTIES; TITANIUM; WATER; X-RAY MICROTOMOGRAPHY;

EID: 84862810507     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.01.040     Document Type: Article

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