Surface mineralization of Ti6Al4V substrates with calcium apatites for the retention and local delivery of recombinant human bone morphogenetic protein-2

Acta Biomaterialia

Volumn 7, Issue 9, 2011, Pages 3488-3495

  Liu, Pingsheng ^a   Smits, Jonathan ^a   Ayers, David C ^a   Song, Jie ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Biomineralization; Calcium apatite; Osteoinductivity; Recombinant human bone morphogenetic protein 2; Titanium alloys

Indexed keywords

ALUMINUM ALLOYS; BIOMINERALIZATION; BONE; CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; DECOMPOSITION; HYDROXYAPATITE; METABOLISM; MINERALOGY; MOLYBDENUM ALLOYS; PROSTHETICS; RECOMBINANT PROTEINS; SCANNING ELECTRON MICROSCOPY; SUBSTRATES; TERNARY ALLOYS; UREA; VANADIUM ALLOYS;

BONE MORPHOGENETIC PROTEIN-2; CALCIUM APATITES; HUMAN BONE MORPHOGENETIC PROTEIN; IN-VITRO; LOCAL DELIVERY; OSTEOGENIC; OSTEOINDUCTIVITY; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; SURFACE MINERALIZATION; TITANIUM (ALLOYS);

TITANIUM ALLOYS;

CALCIUM APATITE; CALCIUM DERIVATIVE; CALCIUM ION; PHOSPHATE BUFFERED SALINE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; TANTALUM; TITANIUM; UNCLASSIFIED DRUG;

ACIDITY; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BODY FLUID; BONE MINERALIZATION; CELL DIFFERENTIATION; CONTACT ANGLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG PROTEIN BINDING; DRUG RELEASE; DRUG RETENTION; ENZYME LINKED IMMUNOSORBENT ASSAY; MICROSCOPY; MOUSE; MYOBLAST; NONHUMAN; OSTEOBLAST; PARTICLE SIZE; PH; POROSITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SIMULATED BODY FLUID; SURFACE PROPERTY;

EID: 79961007982     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.05.025     Document Type: Article

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