Chelation controlled reductive amination of cyclic ketones to trans-4-methoxycyclohexylamines: 9-BBN reduction mediated with FeCl 3

Tetrahedron Letters

Volumn 53, Issue 15, 2012, Pages 1982-1986

  Qu, Bo ^a   Haddad, Nizar ^a   Rodriguez, Sonia ^a   Lee, Heewon ^a   Ma, Shengli ^a   Zeng, Xingzhong ^a   Reeves, Diana C ^a   Sidhu, Kanwar P S ^a   Lorenz, Jon C ^a   Grinberg, Nelu ^a   Busacca, Carl A ^a   Krishnamurthy, Dhileepkumar ^a   Senanayake, Chris H ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

9 BBN; Chelation; Diastereoselective; FeCl 3; Reductive amination

Indexed keywords

CYCLOHEXYLAMINE DERIVATIVE; FERROUS CHLORIDE; KETONE;

AMINATION; ARTICLE; CHELATION; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE;

EID: 84862805276     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2012.02.023     Document Type: Article

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