Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin

Virology

Volumn 426, Issue 2, 2012, Pages 143-151

  Alam, Intekhab ^a   Lee, Ji Hye ^a   Cho, Ki Joon ^a   Han, Kang Rok ^b   Yang, Jai Myung ^b   Chung, Mi Sook ^c   Kim, Kyung Hyun ^a  

^a Korea University   (South Korea)

^b Sogang University   (South Korea)

^c Duksung Women's University   (South Korea)

Author keywords

2 thiouridine; Crystal structure; Norovirus; Ribavirin; RNA dependent RNA polymerase; Viral inhibition

Indexed keywords

2 THIOURIDINE; NUCLEOSIDE DERIVATIVE; RIBAVIRIN; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOLOGY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; GROWTH INHIBITION; MOUSE; MURINE NOROVIRUS 1; NONHUMAN; NOROVIRUS; PRIORITY JOURNAL; STRUCTURE ANALYSIS; VIROGENESIS; VIRUS INHIBITION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CRYSTALLOGRAPHY, X-RAY; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NOROVIRUS; PROTEIN BINDING; RIBAVIRIN; RNA REPLICASE; THIOURIDINE; VIRAL PROTEINS; VIRUS REPLICATION;

CALICIVIRIDAE; MURINE NOROVIRUS 1; NOROVIRUS;

EID: 84862798286     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2012.01.016     Document Type: Article

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