Replacement of microglial cells using Clodronate liposome and bone marrow transplantation in the central nervous system of SOD1G93A transgenic mice as an in vivo model of amyotrophic lateral sclerosis

Biochemical and Biophysical Research Communications

Volumn 418, Issue 2, 2012, Pages 359-365

  Lee, Jae Chul ^a,b   Seong, Jinsil ^b   Kim, Seung Hyun ^c   Lee, Se Jeong ^d   Cho, Yu Jin ^a   An, Jaeyeol ^a   Nam, Do Hyun ^d   Joo, Kyeung Min ^a   Cha, Choong Ik ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Hanyang University   (South Korea)

^d Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Amyotrophic lateral sclerosis (ALS); Bone marrow transplantation (BMT); Clodronate liposome; Microglia; SOD1G93A transgenic mice

Indexed keywords

CLODRONIC ACID; COPPER ZINC SUPEROXIDE DISMUTASE; GREEN FLUORESCENT PROTEIN; LIPOSOME; PHOSPHATE BUFFERED SALINE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; BRAIN VENTRICLE; CELL COUNT; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE COURSE; IMMUNOTOXICITY; IN VIVO STUDY; MACROPHAGE; MALE; MICROENVIRONMENT; MICROGLIA; MONOCYTE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEREOTACTIC TREATMENT; SURVIVAL; TRANSGENIC MOUSE; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BONE MARROW TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; CLODRONIC ACID; DISEASE MODELS, ANIMAL; INJECTIONS, INTRAVENTRICULAR; LIPOSOMES; MICE; MICE, TRANSGENIC; MICROGLIA; MUTATION; SUPEROXIDE DISMUTASE;

MUS; MUS MUSCULUS;

EID: 84862790994     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.01.026     Document Type: Article

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