Hypertension-attenuating effect of whey protein hydrolysate on spontaneously hypertensive rats

Food Chemistry

Volumn 134, Issue 1, 2012, Pages 122-126

  Wang, Xu ^a   Wang, Lei ^a   Cheng, Xue ^a   Zhou, Jie ^a   Tang, Xi ^a   Mao, Xue Ying ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

ACE activity; Antihypertensive effect; Spontaneously hypertensive rat (SHR); Whey protein hydrolysate

Indexed keywords

ABDOMINAL AORTA; ACE-INHIBITORY ACTIVITY; ANGIOTENSIN I-CONVERTING ENZYME; ANTIHYPERTENSIVE EFFECT; DOSE-DEPENDENT MANNER; HEART RATES; INHIBITORY ACTIVITY; NEGATIVE CONTROL; ORAL ADMINISTRATION; SHORT TERM; SPONTANEOUSLY HYPERTENSIVE RAT (SHR); SPONTANEOUSLY HYPERTENSIVE RATS; SYSTOLIC BLOOD PRESSURE; WHEY PROTEIN HYDROLYSATES;

BLOOD PRESSURE; HYDROLYSIS;

OILS AND FATS;

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; MILK PROTEIN; UNCLASSIFIED DRUG; WHEY PROTEIN HYDROLYSATE;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE RESPONSE; DRUG SYNTHESIS; ENZYME ACTIVITY; HYPERTENSION; KIDNEY; LONG TERM CARE; LUNG; MALE; NONHUMAN; RAT; SHORT COURSE THERAPY; SPONTANEOUSLY HYPERTENSIVE HEART FAILURE RAT; SUPPLEMENTATION; SYSTOLIC BLOOD PRESSURE; TISSUE HOMOGENATE; TREATMENT DURATION;

RATTUS;

EID: 84862790774     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.02.074     Document Type: Article

References (29)

1. A. Abubakar, T. Saito, H. Kitazawa, Y. Kawai, and T. Itoh Structural analysis of new antihypertensive peptides derived from cheese whey protein by proteinase K digestion Journal of Dairy Science 81 12 1998 3131 3138
2. M. Azizi, G. Chatellier, T. Guyene, D. Murieta-Geoffroy, and J. Ménard Additive effects of combined angiotensin-converting enzyme-inhibition and angiotensin-II antagonism on blood-pressure and renin release in sodium-depleted normotensinves Circulation 92 4 1995 825 834
3. R.C. Boerth, J.W. Covell, P.E. Pool, and J. Ross Increased myocardial oxygen consumption and contractile state associated with increased heart rate in dogs Circulation Research 24 1969 725 734
4. P. Bruneval, N. Hinglais, F. Alhenc-Gelas, V. Tricottet, P. Corvol, and J. Menard Angiotensin I converting enzyme in human intestine and kidney Histochemistry and Cell Biology 85 1 1986 73 80
5. J. Chen, T. Okada, K. Muramoto, K. Suetsuna, and S. Yang Identification of angiotensin I-converting enzyme inhibitory peptides derived from the peptic digest of soybean protein Journal of Food Biochemistry 26 6 2002 543 554
6. D.W. Cushman, and H.S. Cheung Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung Biochemical Pharmacology 20 7 1971 1637 1648
7. E.G. Erdos Angiotensin I converting enzyme Circulation Research 36 2 1975 247 255
8. R.J. FitzGerald, and H. Meisel Lactokinins: Whey protein-derived ACE inhibitory peptides Food/Nahrung 43 3 1999 165 167
9. M.W. Gillman, W.B. Kannel, A. Belanger, and R.B. D'Agostino Influence of heart rate on mortality among persons with hypertension: The Framingham study American Heart Journal 125 4 1993 1148 1154
10. L. Hansson, L.H. Lindholm, L. Niskanen, J. Lanke, T. Hedner, and A. Niklason Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPPP) randomised trial The Lancet 353 9153 1999 611 616
11. B. Hernandez-Ledesma, M. Del Mar Contreras, and I. Recio Antihypertensive peptides: Production, bioavailability and incorporation into foods Advances in Colloid and Interface Science 165 1 2011 23 35
12. S. Kumar, H.K.L. Tandon, and S. Kapila Antihypertensive and immunomodulatory property of enzyme hydrolysates derived from goat casein Milchwissenschaft-Milk Science International 66 1 2011 40 42
13. G. Li, G. Le, Y. Shi, and S. Shrestha Angiotensin I-converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects Nutrition Research 24 7 2004 469 486
14. J.S. Li, A.M. Sharifi, and E.L. Schiffrin Effect of AT1 angiotensin-receptor blockade on structure and function of small arteries in SHR Journal of Cardiovascular Pharmacology 30 1 1997 75 83
15. H. Meisel, and E. Schlimme Inhibitors of angiotensin converting enzyme derived from bovine casein (casokinins) V. Brantl, H. Teschemacher, β-Casomorphins and related peptides: Recent development 1994 VCH Weinheim 27 33
16. National Research Council (1985). National Research Council Guide for the Care and the Use of Laboratory Animals, Publication nos. 85-23(rev.). National Institutes of Health, Bethesda, MD.
17. D.E. Papadogiannis, and A.D. Protogerou Blood pressure variability: A confounder and a cardiovascular risk factor Hypertension Research 34 2 2011 162 163
18. M. Paul, J. Bachmann, and D. Ganten The tissue renin-angiotensin systems in cardiovascular disease Trends in Cardiovascular Medicine 2 3 1992 94 99
19. M. Phelan, and D. Kerins The potential role of milk-derived peptides in cardiovascular disease Food & Function 2 3-4 2011 153 167
20. A. Pihlanto, T. Virtanen, and H. Korhonen Angiotensin I converting enzyme (ACE) inhibitory activity and antihypertensive effect of fermented milk International Dairy Journal 20 1 2010 3 10
21. Y.M. Pinto, M. Paul, and D. Ganten Lessons from rat models of hypertension: From Goldblatt to genetic engineering Cardiovascular Research 39 1 1998 77 88
22. M. Takemoto, K. Egashira, M. Usui, K. Numaguchi, H. Tomita, and H. Tsutsui Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats The Journal of Clinical Investigation 99 2 1997 278 287
23. A.J. Turner, and N.M. Hooper The angiotensin-converting enzyme gene family: Genomics and pharmacology Trends in Pharmacological Sciences 23 4 2002 177 183
24. J. Wang, J. Hu, J. Cui, X. Bai, Y. Du, and Y. Miyaguchi Purification and identification of a ACE inhibitory peptide from oyster proteins hydrolysate and the antihypertensive effect of hydrolysate in spontaneously hypertensive rats Food Chemistry 111 2 2008 302 308
25. L. Wang, X. Mao, X. Cheng, X. Xiong, and F. Ren Effect of enzyme type and hydrolysis conditions on the in vitro angiotensin I-converting enzyme inhibitory activity and ash content of hydrolysed whey protein isolate International Journal of Food Science & Technology 45 4 2010 807 812
26. J. Wu, R.E. Aluko, and A.D. Muir Improved method for direct high-performance liquid chromatography assay of angiotensin-converting enzyme-catalyzed reactions Journal of Chromatography A 950 1-2 2002 125 130
27. J.N. Wu, and K.H. Berecek Prevention of genetic-hypertension by early treatment of spontaneously hypertensive rats with the angiotensin-converting enzyme-inhibitor captopril Hypertension 22 2 1993 139 146
28. N. Yamamoto, M. Maeno, and T. Takano Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented by Lactobacillus helveticus CPN4 Journal of Dairy Science 82 7 1999 1388 1393
29. F. Zhang, Z. Wang, and S. Xu Macroporous resin purification of grass carp fish (Ctenopharyngodon idella) scale peptides with in vitro angiotensin-I converting enzyme (ACE) inhibitory ability Food Chemistry 117 3 2009 387 392