-
1
-
-
0027953703
-
Banting lecture: Insulin action, diabetogenes, and the cause of type II diabetes
-
Kahn CR. Banting lecture: insulin action, diabetogenes, and the cause of type II diabetes. Diabetes. 1994;43:1066-1084. (Pubitemid 24230714)
-
(1994)
Diabetes
, vol.43
, Issue.8
, pp. 1066-1084
-
-
Kahn, C.R.1
-
2
-
-
0034813837
-
Obesity, free fatty acids, and insulin resistance
-
DOI 10.1097/00060793-200110000-00002
-
Boden G. Obesity, free fatty acids, and insulin resistance. Curr Opin Endocrinol Diabetes. 2001;8:235-239. (Pubitemid 32928276)
-
(2001)
Current Opinion in Endocrinology and Diabetes
, vol.8
, Issue.5
, pp. 235-239
-
-
Boden, G.1
-
3
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest. 2000;106:171-176. (Pubitemid 30483118)
-
(2000)
Journal of Clinical Investigation
, vol.106
, Issue.2
, pp. 171-176
-
-
Shulman, G.I.1
-
5
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
-
DOI 10.1038/23948
-
Yin M-J, Yamamoto Y, Gaynor RB. The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β. Nature. 1998;396:77-80. (Pubitemid 28520452)
-
(1998)
Nature
, vol.396
, Issue.6706
, pp. 77-80
-
-
Yin, M.-J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
6
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
DOI 10.1172/JCI28898
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest. 2006;116:3015-3025. (Pubitemid 44684486)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
7
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-βB
-
DOI 10.1038/nm1166
-
Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE. Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-βB. Nat Med. 2005;11:183-190. (Pubitemid 40321354)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
8
-
-
33847754623
-
The JNK signal transduction pathway
-
DOI 10.1016/j.ceb.2007.02.001, PII S0955067407000154
-
Weston CR, Davis RJ. The JNK signal transduction pathway. Curr Opin Cell Biol. 2007;19:142-149. (Pubitemid 46386399)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.2
, pp. 142-149
-
-
Weston, C.R.1
Davis, R.J.2
-
9
-
-
12144290761
-
Differential Effects of Interleukin-6 and -10 on Skeletal Muscle and Liver Insulin Action In Vivo
-
DOI 10.2337/diabetes.53.4.1060
-
Kim H-J, Higashimori T, Park S-Y, Choi H, Dong J, Kim Y-J, Noh H-L, Cho Y-R, Cline GW, Kim Y-B, Kim JK. Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo. Diabetes. 2004;53:1060-1067. (Pubitemid 38436619)
-
(2004)
Diabetes
, vol.53
, Issue.4
, pp. 1060-1067
-
-
Kim, H.-J.1
Higashimori, T.2
Park, S.-Y.3
Choi, H.4
Dong, J.5
Kim, Y.-J.6
Noh, H.-L.7
Cho, Y.-R.8
Cline, G.9
Kim, Y.-B.10
Kim, J.K.11
-
10
-
-
0034903710
-
Prevention of fat-induced insulin resistance by salicylate
-
DOI 10.1172/JCI200111559
-
Kim JK, Kim Y-J, Fillmore JJ, Chen Y, Moore I, Lee J, Yuan M, Li ZW, Karin M, Perret P, Shoelson SE, Shulman GI. Prevention of fat-induced insulin resistance by salicylate. J Clin Invest. 2001;108:437-446. (Pubitemid 32730790)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.3
, pp. 437-446
-
-
Kim, J.K.1
Kim, Y.-J.2
Fillmore, J.J.3
Chen, Y.4
Moore, I.5
Lee, J.6
Yuan, M.7
Li, Z.W.8
Karin, M.9
Perret, P.10
Shoelson, S.E.11
Shulman, G.I.12
-
11
-
-
0036099857
-
Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes
-
DOI 10.1172/JCI200214955
-
Hundal RS, Petersen KF, Mayerson AB, Randhawa PS, Inzucchi S, Shoelson SE, Shulman GI. Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. J Clin Invest. 2002;109:1321-1326. (Pubitemid 34546896)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.10
, pp. 1321-1326
-
-
Hundal, R.S.1
Petersen, K.F.2
Mayerson, A.B.3
Randhawa, P.S.4
Inzucchi, S.5
Shoelson, S.E.6
Shulman, G.I.7
-
12
-
-
70350561703
-
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle
-
Hong E-G, Ko HJ, Cho Y-R, Kim H-J, Ma Z, Yu T, Friedline RH, Kurt-Jones E, Finberg R, Fischer MA, Granger EL, Norbury CC, Hauschka SD, Philbrick WM, Lee C-G, Elias JA, Kim JK. Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes. 2009;58:2525-2535.
-
(2009)
Diabetes
, vol.58
, pp. 2525-2535
-
-
Hong, E.-G.1
Ko, H.J.2
Cho, Y.-R.3
Kim, H.-J.4
Ma, Z.5
Yu, T.6
Friedline, R.H.7
Kurt-Jones, E.8
Finberg, R.9
Fischer, M.A.10
Granger, E.L.11
Norbury, C.C.12
Hauschka, S.D.13
Philbrick, W.M.14
Lee, C.-G.15
Elias, J.A.16
Kim, J.K.17
-
13
-
-
84857914467
-
Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs lifespans
-
Hasegawa Y, Saito T, Ogihara T, Ishigaki Y, Yamada T, Imai J, Uno K, Gao J, Kaneko K, Shimosawa T, Asano T, Fujita T, Oka Y, Katagiri H. Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs lifespans. Circulation. 2012;125:1122-1133.
-
(2012)
Circulation
, vol.125
, pp. 1122-1133
-
-
Hasegawa, Y.1
Saito, T.2
Ogihara, T.3
Ishigaki, Y.4
Yamada, T.5
Imai, J.6
Uno, K.7
Gao, J.8
Kaneko, K.9
Shimosawa, T.10
Asano, T.11
Fujita, T.12
Oka, Y.13
Katagiri, H.14
-
14
-
-
14244269416
-
On the treatment of glycosuria and diabetes mellitus with sodium salicylate
-
Williamson RT. On the treatment of glycosuria and diabetes mellitus with sodium salicylate. BMJ. 1901;1:760-762.
-
(1901)
BMJ
, vol.1
, pp. 760-762
-
-
Williamson, R.T.1
-
15
-
-
77950885686
-
The effects of salsalate on glycemic control in patients with type 2 diabetes. A randomized trial
-
Goldfine AB, Fonseca V, Jablonski KA, Pyle L, Staten MA, Shoelson SE. The effects of salsalate on glycemic control in patients with type 2 diabetes. A randomized trial. Ann Intern Med. 2010;152:346-357.
-
(2010)
Ann Intern Med
, vol.152
, pp. 346-357
-
-
Goldfine, A.B.1
Fonseca, V.2
Jablonski, K.A.3
Pyle, L.4
Staten, M.A.5
Shoelson, S.E.6
-
16
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259:87-91. (Pubitemid 23036092)
-
(1993)
Science
, vol.259
, Issue.5091
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
17
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
DOI 10.1172/JCI200319246
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112:1796-1808. (Pubitemid 38063703)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
18
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
DOI 10.1172/JCI200319451
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112:1821-1830. (Pubitemid 38063705)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
19
-
-
57349101675
-
A stress signaling pathway in adipose tissue regulates hepatic insulin resistance
-
Sabio G, Das M, Mora A, Zhang Z, Jun JY, Ko HJ, Barrett T, Kim JK, Davis RJ. A stress signaling pathway in adipose tissue regulates hepatic insulin resistance. Science. 2008;322:1539 -1543.
-
(2008)
Science
, vol.322
, pp. 1539-1543
-
-
Sabio, G.1
Das, M.2
Mora, A.3
Zhang, Z.4
Jun, J.Y.5
Ko, H.J.6
Barrett, T.7
Kim, J.K.8
Davis, R.J.9
-
20
-
-
33644672230
-
Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice
-
Park S-Y, Cho Y-R, Kim H-J, Higashimori T, Danton C, Lee M-K, Dey A, Rothermel B, Kim Y-B, Kalinowski A, Russell KS, Kim JK. Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice. Diabetes. 2005;54:3530 -3540.
-
(2005)
Diabetes
, vol.54
, pp. 3530-3540
-
-
Park, S.-Y.1
Cho, Y.-R.2
Kim, H.-J.3
Higashimori, T.4
Danton, C.5
Lee, M.-K.6
Dey, A.7
Rothermel, B.8
Kim, Y.-B.9
Kalinowski, A.10
Russell, K.S.11
Kim, J.K.12
-
21
-
-
0034577768
-
Raised interleukin-6 levels in obese patients
-
Roytblat L, Rachinsky M, Fisher A, Greemberg L, Shapira Y, Douvdevani A, Gelman S. Raised interleukin-6 levels in obese patients. Obes Res. 2000;8:673- 675.
-
(2000)
Obes Res
, vol.8
, pp. 673-675
-
-
Roytblat, L.1
Rachinsky, M.2
Fisher, A.3
Greemberg, L.4
Shapira, Y.5
Douvdevani, A.6
Gelman, S.7
-
22
-
-
77951918926
-
Macrophages, inflammation, and insulin resistance
-
Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol. 2010;72:219 -246.
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 219-246
-
-
Olefsky, J.M.1
Glass, C.K.2
-
23
-
-
80053128750
-
New insights into insulin resistance in the diabetic heart
-
Gray S, Kim JK. New insights into insulin resistance in the diabetic heart. Trends Endocrinol Metab. 2011;22:394-403.
-
(2011)
Trends Endocrinol Metab
, vol.22
, pp. 394-403
-
-
Gray, S.1
Kim, J.K.2
-
24
-
-
0027390858
-
Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure
-
Baron AD, Brechtel-Hook G, Johnson A, Hardin D. Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure. Hypertension. 1993;21:129 -135.
-
(1993)
Hypertension
, vol.21
, pp. 129-135
-
-
Baron, A.D.1
Brechtel-Hook, G.2
Johnson, A.3
Hardin, D.4
-
25
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and drosophila
-
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvari M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila A-M, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D. Absence of effects of Sir2 overexpression on lifespan in C. elegans and drosophila. Nature. 2011;477:482- 486.
-
(2011)
Nature
, vol.477
, pp. 482-486
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
Goss, M.4
Somogyvari, M.5
Piper, M.D.6
Hoddinott, M.7
Sutphin, G.L.8
Leko, V.9
McElwee, J.J.10
Vazquez-Manrique, R.P.11
Orfila, A.-M.12
Ackerman, D.13
Au, C.14
Vinti, G.15
Riesen, M.16
Howard, K.17
Neri, C.18
Bedalov, A.19
Kaeberlein, M.20
Soti, C.21
Partridge, L.22
Gems, D.23
more..
-
26
-
-
0022481133
-
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
-
Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell. 1986;46:705-716. (Pubitemid 16020062)
-
(1986)
Cell
, vol.46
, Issue.5
, pp. 705-716
-
-
Sen, R.1
Baltimore, D.2
|