New inhibitor of 3-phosphoinositide dependent protein kinase-1 identified from virtual screening

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1629-1632

  Yang, Wenchao ^a,b   AbdulHameed, Mohamed Diwan M ^b   Hamza, Adel ^b   Zhan, Chang Guo ^b  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

^b University of Kentucky   (United States)

Author keywords

Anticancer activity; Enzyme; Enzyme inhibitor; Inhibitor identification

Indexed keywords

ANTINEOPLASTIC AGENT; CELECOXIB; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1 INHIBITOR; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL VIABILITY; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LEUKEMIA; LUNG NON SMALL CELL CANCER; MALE; MELANOMA; OVARY CANCER; PROSTATE CANCER;

EID: 84862783730     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.121     Document Type: Article

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