Cytotoxic and pro-apoptotic effects of novel ganoderic acid derivatives on human cervical cancer cells in vitro

European Journal of Pharmacology

Volumn 681, Issue 1-3, 2012, Pages 23-33

  Liu, Ru Ming ^a   Li, Ying Bo ^a   Zhong, Jian Jiang ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Shanghai Jiao Tong University   (China)

Author keywords

Caspase; Cell apoptosis; Cervical cancer; Ganoderic acid derivative; Ganoderma lucidum; Mitochondrial membrane potential

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3ALPHA, 15ALPHA, 22 TRIACETOXY 5ALPHA LANOSTA 7,9(11), 24 TRIEN 26 OIC ACID AMIDE; 3ALPHA, 15ALPHA, 22 TRIACETOXY 5ALPHA LANOSTA 7,9(11), 24 TRIEN 26 OIC ACID ETHYL ESTER; 3ALPHA, 15ALPHA, 22 TRIACETOXY 5ALPHA LANOSTA 7,9(11), 24 TRIEN 26 OIC ACID METHYL ESTER; 3ALPHA, 15ALPHA, 22 TRIACETOXY 5ALPHA LANOSTA 7,9(11), 24 TRIEN 26 OIC ACID PROPYL ESTER; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYTOTOXIC AGENT; DNA; GANODERIC ACID T; NATURAL PRODUCT; PLANT MEDICINAL PRODUCT; TRITERPENOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL DESTRUCTION; CELL GROWTH; CELL LOSS; CELL PROLIFERATION; CELL STRUCTURE; COMPARATIVE EFFECTIVENESS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HELA CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; UTERINE CERVIX CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINTS; HELA CELLS; HUMANS; LANOSTEROL; MEMBRANE POTENTIAL, MITOCHONDRIAL; UTERINE CERVICAL NEOPLASMS;

EID: 84862782073     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.02.007     Document Type: Article

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