-
1
-
-
77955178608
-
Surgical implication of micrometastasis for pancreatic cancer
-
Kayahara M, Funaki K, Tajima H, Takamura H, Ninomiya I, Kitagawa H, Ohta T: Surgical implication of micrometastasis for pancreatic cancer. Pancreas 2010; 39: 884-888.
-
(2010)
Pancreas
, vol.39
, pp. 884-888
-
-
Kayahara, M.1
Funaki, K.2
Tajima, H.3
Takamura, H.4
Ninomiya, I.5
Kitagawa, H.6
Ohta, T.7
-
2
-
-
77954023412
-
Adjuvant therapy and survival after resection of pancreatic adenocarcinoma: A population-based analysis
-
Mayo SC, Austin DF, Sheppard BC, Mori M, Shipley DK, Billingsley KG: Adjuvant therapy and survival after resection of pancreatic adenocarcinoma: A population-based analysis. Cancer 2010; 116: 2932-2940.
-
(2010)
Cancer
, vol.116
, pp. 2932-2940
-
-
Mayo, S.C.1
Austin, D.F.2
Sheppard, B.C.3
Mori, M.4
Shipley, D.K.5
Billingsley, K.G.6
-
3
-
-
77749285628
-
Updates in adjuvant therapy in pancreatic cancer: Gemcitabine and beyond
-
Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium' Orlando USA
-
Richter J, Saif MW: Updates in adjuvant therapy in pancreatic cancer: Gemcitabine and beyond. Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium', Orlando, USA. JOP 2010; 11: 144-147.
-
(2010)
JOP
, vol.11
, pp. 144-147
-
-
Richter, J.1
Saif, M.W.2
-
4
-
-
1642588228
-
Pancreatic cancer
-
DOI 10.1016/S0140-6736(04)15841-8, PII S0140673604158418
-
Li D, Xie K, Wolff R, Abbruzzese JL: Pancreatic cancer. Lancet 2004; 363: 1049-1057. (Pubitemid 38410779)
-
(2004)
Lancet
, vol.363
, Issue.9414
, pp. 1049-1057
-
-
Li, D.1
Xie, K.2
Wolff, R.3
Abbruzzese, J.L.4
-
5
-
-
0037212983
-
Hedgehog signaling in pancreas development
-
DOI 10.1016/S0925-4773(02)00331-3, PII S0925477302003313
-
Hebrok M: Hedgehog signaling in pancreas development. Mech Dev 2003; 120: 45-57. (Pubitemid 35462095)
-
(2003)
Mechanisms of Development
, vol.120
, Issue.1
, pp. 45-57
-
-
Hebrok, M.1
-
6
-
-
77954227128
-
The role of the Hedgehog signaling pathway in the development of basal cell carcinoma and opportunities for treatment
-
Caro I, Low JA: The role of the Hedgehog signaling pathway in the development of basal cell carcinoma and opportunities for treatment. Clin Cancer Res 2010; 16: 3335-3339.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3335-3339
-
-
Caro, I.1
Low, J.A.2
-
7
-
-
67649233042
-
The Hedgehog pathway as a therapeutic target for treatment of breast cancer
-
Barginear MF, Leung M, Budman DR: The Hedgehog pathway as a therapeutic target for treatment of breast cancer. Breast Cancer Res Treat 2009; 116: 239-246.
-
(2009)
Breast Cancer Res Treat
, vol.116
, pp. 239-246
-
-
Barginear, M.F.1
Leung, M.2
Budman, D.R.3
-
8
-
-
77953362373
-
Hedgehog signaling and gastrointestinal cancer
-
Saqui-Salces M, Merchant JL: Hedgehog signaling and gastrointestinal cancer. Biochim Biophys Acta 2010; 1803: 786-795.
-
(2010)
Biochim Biophys Acta
, vol.1803
, pp. 786-795
-
-
Saqui-Salces, M.1
Merchant, J.L.2
-
9
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
DOI 10.1038/nature02009
-
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M: Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003; 425: 851-856. (Pubitemid 37355945)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 851-856
-
-
Thayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
10
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S, Zhang X, Parsons DW, et al: Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008; 321: 1801-1806.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
-
11
-
-
52649169761
-
Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer
-
Feldmann G, Habbe N, Dhara S, Bisht S, Alvarez H, Fendrich V, Beaty R, Mullendore M, Karikari C, Bardeesy N, Ouellette MM, Yu W, Maitra A: Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer. Gut 2008; 57: 1420-1430.
-
(2008)
Gut
, vol.57
, pp. 1420-1430
-
-
Feldmann, G.1
Habbe, N.2
Dhara, S.3
Bisht, S.4
Alvarez, H.5
Fendrich, V.6
Beaty, R.7
Mullendore, M.8
Karikari, C.9
Bardeesy, N.10
Ouellette, M.M.11
Yu, W.12
Maitra, A.13
-
13
-
-
69249156565
-
Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer
-
Mueller MT, Hermann PC, Witthauer J, Rubio-Viqueira B, Leicht SF, Huber S, Ellwart JW, Mustafa M, Bartenstein P, D'Haese JG, Schoenberg MH, Berger F, Jauch KW, Hidalgo M, Heeschen C: Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer. Gastroenterology 2009; 137: 1102-1113.
-
(2009)
Gastroenterology
, vol.137
, pp. 1102-1113
-
-
Mueller, M.T.1
Hermann, P.C.2
Witthauer, J.3
Rubio-Viqueira, B.4
Leicht, S.F.5
Huber, S.6
Ellwart, J.W.7
Mustafa, M.8
Bartenstein, P.9
D'Haese, J.G.10
Schoenberg, M.H.11
Berger, F.12
Jauch, K.W.13
Hidalgo, M.14
Heeschen, C.15
-
14
-
-
60849118097
-
A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development
-
Jimeno A, Feldmann G, Suárez-Gauthier A, Rasheed Z, Solomon A, Zou GM, Rubio-Viqueira B, García-García E, López-Ríos F, Matsui W, Maitra A, Hidalgo M: A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development. Mol Cancer Ther 2009; 8: 310-314.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 310-314
-
-
Jimeno, A.1
Feldmann, G.2
Suárez-Gauthier, A.3
Rasheed, Z.4
Solomon, A.5
Zou, G.M.6
Rubio-Viqueira, B.7
García-García, E.8
López-Ríos, F.9
Matsui, W.10
Maitra, A.11
Hidalgo, M.12
-
15
-
-
73449100838
-
Resveratrol: Its biologic targets and functional activity
-
Pervaiz S, Holme AL: Resveratrol: Its biologic targets and functional activity. Antioxid Redox Signal 2009; 11: 2851-2897.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2851-2897
-
-
Pervaiz, S.1
Holme, A.L.2
-
16
-
-
0031561513
-
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
-
Jang M, Cai L, Udeani GO, et al: Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997; 275: 218-220. (Pubitemid 127696281)
-
(1997)
Science
, vol.275
, Issue.5297
, pp. 218-220
-
-
Jang, M.1
Cai, L.2
Udeani, G.O.3
Slowing, K.V.4
Thomas, C.F.5
Beecher, C.W.W.6
Fong, H.H.S.7
Farnsworth, N.R.8
Kinghorn, A.D.9
Mehta, R.G.10
Moon, R.C.11
Pezzuto, J.M.12
-
17
-
-
78049440850
-
Antiproliferative effect of resveratrol in pancreatic cancer cells
-
Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM: Antiproliferative effect of resveratrol in pancreatic cancer cells. Phytother Res 2010; 24: 1637-1644.
-
(2010)
Phytother Res
, vol.24
, pp. 1637-1644
-
-
Jang, M.1
Cai, L.2
Udeani, G.O.3
Slowing, K.V.4
Thomas, C.F.5
Beecher, C.W.6
Fong, H.H.7
Farnsworth, N.R.8
Kinghorn, A.D.9
Mehta, R.G.10
Moon, R.C.11
Pezzuto, J.M.12
-
18
-
-
78649927272
-
Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene a4 hydrolase
-
Oi N, Jeong CH, Nadas J, Cho YY, Pugliese A, Bode AM, Dong Z: Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene a4 hydrolase. Cancer Res 2010; 70: 9755-9764.
-
(2010)
Cancer Res
, vol.70
, pp. 9755-9764
-
-
Oi, N.1
Jeong, C.H.2
Nadas, J.3
Cho, Y.Y.4
Pugliese, A.5
Bode, A.M.6
Dong, Z.7
-
19
-
-
77953703732
-
Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer
-
Harikumar KB, Kunnumakkara AB, Sethi G, Diagaradjane P, Anand P, Pandey MK, Gelovani J, Krishnan S, Guha S, Aggarwal BB: Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer. Int J Cancer 2010; 127: 257-268.
-
(2010)
Int J Cancer
, vol.127
, pp. 257-268
-
-
Harikumar, K.B.1
Kunnumakkara, A.B.2
Sethi, G.3
Diagaradjane, P.4
Anand, P.5
Pandey, M.K.6
Gelovani, J.7
Krishnan, S.8
Guha, S.9
Aggarwal, B.B.10
-
20
-
-
79954522869
-
Identification of RegIV as a novel GLI1 target gene in human pancreatic cancer
-
Wang F, Xu L, Guo C, Ke A, Hu G, Xu X, Mo W, Yang L, Huang Y, He S, Wang X: Identification of RegIV as a novel GLI1 target gene in human pancreatic cancer. PloS One 2011; 11:e18434.
-
(2011)
PloS One
, vol.11
-
-
Wang, F.1
Xu, L.2
Guo, C.3
Ke, A.4
Hu, G.5
Xu, X.6
Mo, W.7
Yang, L.8
Huang, Y.9
He, S.10
Wang, X.11
-
21
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ: Cancer Statistics, 2009. CA Cancer J Clin 2009; 59: 225-249.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
22
-
-
6944250259
-
Role of resveratrol in prevention and therapy of cancer: Preclinical and clinical studies
-
Aggarwal BB, Bhardwaj A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y: Role of resveratrol in prevention and therapy of cancer: Preclinical and clinical studies. Anticancer Res 2004; 24: 2783-2840. (Pubitemid 39409568)
-
(2004)
Anticancer Research
, vol.24
, Issue.5 A
, pp. 2783-2840
-
-
Aggarwal, B.B.1
Bhardwaj, A.2
Aggarwal, R.S.3
Seeram, N.P.4
Shishodia, S.5
Takada, Y.6
-
23
-
-
67349128956
-
Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms
-
Athar M, Back JH, Kopelovich L, Bickers DR, Kim AL: Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms. Arch Biochem Biophys 2009; 486: 95-102.
-
(2009)
Arch Biochem Biophys
, vol.486
, pp. 95-102
-
-
Athar, M.1
Back, J.H.2
Kopelovich, L.3
Bickers, D.R.4
Kim, A.L.5
-
24
-
-
79952801721
-
Resveratrol, a phytochemical inducer of multiple cell death pathways: Apoptosis, autophagy and mitotic catastrophe
-
Delmas D, Solary E, Latruffe N: Resveratrol, a phytochemical inducer of multiple cell death pathways: Apoptosis, autophagy and mitotic catastrophe. Curr Med Chem 2011; 18: 1100-1121.
-
(2011)
Curr Med Chem
, vol.18
, pp. 1100-1121
-
-
Delmas, D.1
Solary, E.2
Latruffe, N.3
-
25
-
-
79551617718
-
Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition
-
Shankar S, Nall D, Tang SN, Meeker D, Passarini J, Sharma J, Srivastava RK: Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition. PLoS One 2011; 6:e16530.
-
(2011)
PLoS One
, vol.6
-
-
Shankar, S.1
Nall, D.2
Tang, S.N.3
Meeker, D.4
Passarini, J.5
Sharma, J.6
Srivastava, R.K.7
-
26
-
-
84868308799
-
Resveratrol MicroRNAs inflammation and cancer
-
Tili E, Michaille JJ: Resveratrol, MicroRNAs, inflammation, and cancer. J Nucl Acids 2011; 2011: 102431.
-
(2011)
J Nucl Acids
, vol.2011
, pp. 102431
-
-
Tili, E.1
Michaille, J.J.2
-
27
-
-
79952641157
-
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines
-
Araújo JR, Gonçalves P, Martel F; Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines. Nutr Res 2011; 31: 77-87.
-
(2011)
Nutr Res
, vol.31
, pp. 77-87
-
-
Araújo, J.R.1
Gonçalves, P.2
Martel, F.3
-
28
-
-
68149124175
-
Blockade of Hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer
-
Xu FG, Ma QY, Wang Z: Blockade of Hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer. Cancer Lett 2009; 283: 119-124.
-
(2009)
Cancer Lett
, vol.283
, pp. 119-124
-
-
Xu, F.G.1
Ma, Q.Y.2
Wang, Z.3
-
29
-
-
34249908943
-
Current understanding of precursors to pancreatic cancer
-
DOI 10.1007/s00534-006-1165-6
-
Takaori K: Current understanding of precursors to pancreatic cancer. J Hepatobiliary Pancreat Surg 2007; 14: 217-223. (Pubitemid 46863909)
-
(2007)
Journal of Hepato-Biliary-Pancreatic Surgery
, vol.14
, Issue.3
, pp. 217-223
-
-
Takaori, K.1
-
30
-
-
70350534843
-
Hedgehog target genes: Mechanisms of carcinogenesis induced by aberrant Hedgehog signaling activation
-
Katoh Y, Katoh M: Hedgehog target genes: Mechanisms of carcinogenesis induced by aberrant Hedgehog signaling activation. Curr Mol Med 2009; 9: 873-886.
-
(2009)
Curr Mol Med
, vol.9
, pp. 873-886
-
-
Katoh, Y.1
Katoh, M.2
-
31
-
-
79960105173
-
Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells
-
Colin D, Limagne E, Jeanningros S, Jacquel A, Lizard G, Athias A, Gambert P, Hichami A, Latruffe N, Solary E, Delmas D: Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells. Cancer Prev Res 2011: 1095-1106.
-
(2011)
Cancer Prev Res
, pp. 1095-1106
-
-
Colin, D.1
Limagne, E.2
Jeanningros, S.3
Jacquel, A.4
Lizard, G.5
Athias, A.6
Gambert, P.7
Hichami, A.8
Latruffe, N.9
Solary, E.10
Delmas, D.11
-
32
-
-
33746951471
-
Selective modulation of hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes
-
DOI 10.1128/MCB.02317-05
-
Kasper M, Schnidar H, Neill GW, Hanneder M, Klingler S, Blaas L, Schmid C, Hauser-Kronberger C, Regl G, Philpott MP, Aberger F: Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes. Mol Cell Biol 2006; 26: 6283-6298. (Pubitemid 44204544)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.16
, pp. 6283-6298
-
-
Kasper, M.1
Schnidar, H.2
Neill, G.W.3
Hanneder, M.4
Klingler, S.5
Blaas, L.6
Schmid, C.7
Hauser-Kronberger, C.8
Regl, G.9
Philpott, M.P.10
Aberger, F.11
-
33
-
-
57749086958
-
Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: A potential new therapeutic target
-
Hegde GV, Peterson KJ, Emanuel K, Mittal AK, Joshi AD, Dickinson JD, Kollessery GJ, Bociek RG, Bierman P, Vose JM, Weisenburger DD, Joshi SS: Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: A potential new therapeutic target. Mol Cancer Res 2008; 6: 1928-1936.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1928-1936
-
-
Hegde, G.V.1
Peterson, K.J.2
Emanuel, K.3
Mittal, A.K.4
Joshi, A.D.5
Dickinson, J.D.6
Kollessery, G.J.7
Bociek, R.G.8
Bierman, P.9
Vose, J.M.10
Weisenburger, D.D.11
Joshi, S.S.12
-
34
-
-
77953615901
-
Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines
-
Wang K, Pan L, Che X, Cui D, Li C: Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines. J Neurooncol 2010; 98: 319-327.
-
(2010)
J Neurooncol
, vol.98
, pp. 319-327
-
-
Wang, K.1
Pan, L.2
Che, X.3
Cui, D.4
Li, C.5
|