Elevated interleukin-27 enhances the polarization of Th1/Tc1 cells and the production of proinflammatory cytokines in primary immune thrombocytopenia

Human Immunology

Volumn 73, Issue 3, 2012, Pages 240-247

  Li, Hui Yuan ^a   Zhang, Dong Lei ^a   Ge, Jing ^a   Zhou, Hu ^a   Qi, Ai Ping ^a   Ma, Li ^a   Xue, Feng ^a   Zhou, Ze Ping ^a,b   Yang, Ren Chi ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Interleukin 27; Primary immune thrombocytopenia; Proinflammatory cytokines; Tc1; Th1

Indexed keywords

BETA ACTIN; DANAZOL; GAMMA INTERFERON; GLUCOCORTICOID; GRANZYME B; IMMUNOGLOBULIN; INTERLEUKIN 27; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNE THROMBOCYTOPENIA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; MALE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; POLARIZATION; PRIMARY IMMUNE THROMBOCYTOPENIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; TH1 CELL; THROMBOCYTE COUNT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CELLS, CULTURED; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKINS; MALE; MIDDLE AGED; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; RECEPTORS, INTERLEUKIN; T-LYMPHOCYTES; TH1-TH2 BALANCE; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 84862778137     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2011.12.010     Document Type: Article

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