Thromboxane A 2 receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment

Toxicology and Applied Pharmacology

Volumn 259, Issue 1, 2012, Pages 104-114

  Minamino, Tsutomu ^a   Ito, Yoshiya ^a   Ohkubo, Hirotoki ^a   Hosono, Kanako ^a   Suzuki, Tatsunori ^a   Sato, Takehito ^a   Ae, Takako ^a   Shibuya, Akitaka ^a   Sakagami, Hiroyuki ^a   Narumiya, Shuh ^b   Koizumi, Wasaburo ^a   Majima, Masataka ^a  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Chemokine; Hepatotoxicity; Macrophage; Regeneration; Thromboxane

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ALANINE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CHEMOKINE RECEPTOR CCR2; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; SCATTER FACTOR; THROMBOXANE A2 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; LIVER CELL; LIVER NECROSIS; LIVER REGENERATION; LIVER TOXICITY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE REPAIR;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; CARBON TETRACHLORIDE; CELL PROLIFERATION; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; INTERLEUKIN-6; LIVER; LIVER REGENERATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CCR2; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 84862777979     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.12.013     Document Type: Article

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