A unique FGF23 with the ability to activate FGFR signaling through both αklotho and βklotho

Journal of Molecular Biology

Volumn 418, Issue 1-2, 2012, Pages 82-89

  Wu, Xinle ^a   Weiszmann, Jennifer ^a   Ge, Hongfei ^a   Baribault, Helene ^a   Stevens, Jennitte ^a   Hawkins, Nessa ^a   Vonderfecht, Steven ^a   Gardner, Jonitha ^a   Gupte, Jamila ^a   Sheng, Jackie ^a   Wang, Minghan ^a   Li, Yang ^a  

^a AMGEN INC   (United States)

Author keywords

FGF19; FGF21; FGF23; Klotho; Klotho

Indexed keywords

FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR 21C; FIBROBLAST GROWTH FACTOR 23; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 1C; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 2C; GLUCOSE; KLOTHO PROTEIN; UNCLASSIFIED DRUG;

ADIPOCYTE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; COMPLEX FORMATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; LIVER CELL; MALE; MOUSE; NONHUMAN; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

MUS;

EID: 84862777904     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.02.027     Document Type: Article

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