IFN-γ deficiency exacerbates experimental autoimmune neuritis in mice despite a mitigated systemic Th1 immune response

Journal of Neuroimmunology

Volumn 246, Issue 1-2, 2012, Pages 18-26

  Zhang, Hong Liang ^a   Azimullah, Sheikh ^b   Zheng, Xiang Yu ^a   Wang, Xiao Ke ^a,c   Amir, Naheed ^b   Mensah Brown, Eric P ^b   Al Shamsi, Mariam ^b   Shahin, Allen ^b   Press, Rayomand ^d   Zhu, Jie ^a,e   Adem, Abdu ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^c THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

Author keywords

Experimental autoimmune neuritis; Guillain Barr syndrome; Interferon gamma; Interleukin 17A; Nitric oxide; T helper 17 cell

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GLYCOPROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23P40; INTERLEUKIN 6; MACROSIALIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CAUDA EQUINA; CELL PROLIFERATION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DEMYELINATING DISEASE; DISEASE SEVERITY; EXPERIMENTAL AUTOIMMUNE NEURITIS; GUILLAIN BARRE SYNDROME; IMMUNE RESPONSE; KNOCKOUT MOUSE; MACROPHAGE; MALE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPLEEN; TH1 CELL; UPREGULATION; WILD TYPE;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; GENETIC PREDISPOSITION TO DISEASE; INTERFERON-GAMMA; MICE; MICE, KNOCKOUT; NEURITIS, AUTOIMMUNE, EXPERIMENTAL; TH1 CELLS; TH17 CELLS; TH2 CELLS; UP-REGULATION;

EID: 84862777775     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2012.02.011     Document Type: Article

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