Suppression of autoimmune neuritis in IFN-γ receptor-deficient mice

Experimental Neurology

Volumn 169, Issue 2, 2001, Pages 472-478

  Zhu, Yu ^a   Ljunggren, Hans Gustaf ^a   Mix, Eilhard ^b   Li, Hu Lun ^a   Van der Meide, Peter ^c   Elhassan, Adlan M ^a   Winblad, Bengt ^a   Zhu, Jie ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Experimental autoimmune neuritis; Guillain Barr syndrome; IFN receptor deficient mice; Th1 Th2 cytokine

Indexed keywords

CD4 ANTIGEN; CYTOKINE; CYTOKINE RECEPTOR; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 4;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; GUILLAIN BARRE SYNDROME; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NEURITIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TH1 CELL; TH2 CELL;

EID: 0034993347     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2001.7662     Document Type: Article

References (36)

1. Molecular transductional mechanisms by which IFN-γ and other signals regulate macrophage development
2. Molecular mimicry and the autoimmune response to the peripheral nerve myelin P0 glycoprotein
3. Modulation of human chrondrocyte metabolism by recombinant human interferon-gamma: In vitro effects on basal and IL-l-stimulated proteinase production, cartilage degradation and DNA synthesis
4. Chemokines and leukocyte traffic
5. Interferon-γ in autoimmunity
6. γ-Interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin-1, and urokinase genes, which are controlled by short-lived repressors
7. Nasal administration of recombinant rat IL-4 ameliorates ongoing experimental autoimmune neuritis and inhibits demyelination
8. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
9. Animal models for autoimmune demyelinating disorders of the nervous system
10. + T cells into IL-4-secreting cells
11. The role of interferon-γ in the pathogenesis of experimental autoimmune disease of the peripheral nervous system
12. + aβ-TCR transgenic T cells is macrophage dependent
13. Identification of the neuritogen for experimental allergic neuritis
14. A permanent rat cell line that mediates experimental allergic neuritis in the Lewis rats in vivo
15. Cell adhesion molecules of the immunoglobulin supergene family as tissue-specific autoantigens: Induction of experimental allergic neuritis (EAN) by P0 protein-specific T cell lines
16. P0 myelin protein produces experimental allergic neuritis in Lewis rats
17. The expanding universe of T-cell subsets: Th1, Th2 and more
18. Synergy between encephalitogenic T cells and protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis
19. Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis
20. Lymphokine production by human T cells in disease states
21. Transfer of demyelination by injection of experimental allergic neuritis serum
22. Lymphokines in autoimmunityA critical review
23. Transient cellular expression of γ-interferon in myelin-induced and T-cell line-mediated experimental autoimmune neuritis
24. + T cells
25. Induction of experimental allergic neuritis with synthetic peptides from myelin P2 protein
26. Humoral factors in peripheral nerve disease
27. Interleukin-12 and interferon-gamma. Do they always go together?
28. Interferon-γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus
29. Allergic neuritis: An experimental disease of rabbits induced by the injection of peripheral nervous tissue and adjuvant
30. Distinct regulation of lymphokine production is found in fresh versus in vitro primed murine helper T cells
31. IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
32. Studies in experimental allergic neuritis. I. Demyelinating patterns studied in vitro
33. Mice with interferon-γ receptor deficient are less susceptible to experimental autoimmune myasthenia gravis
34. Cytokine production and the pathogenesis of experimental allergic neuritis and Guillain-Barré syndrome
35. Th1-like cell responses to peripheral nerve myelin components over the course of experimental allergic neuritis in Lewis rats
36. Cellular mRNA expression of interferon-γ interleukin 4 and transforming growth factor-β by rat monofiuclear cells stimulated with peripheral nerve myelin antigens in experimental allergic neuritis