Corneodesmosin gene ablation induces lethal skinbarrier disruption and hair-follicle degeneration related to desmosome dysfunction

Journal of Cell Science

Volumn 122, Issue 15, 2009, Pages 2699-2709

  Leclerc, Emilie A ^a   Huchenq, Anne ^a   Mattiuzzo, Nicolas R ^a   Metzger, Daniel ^b   Chambon, Pierre ^b   Ghyselinck, Norbert B ^b   Serre, Guy ^a   Jonca, Nathalie ^a   Guerrin, Marina ^a  

^a CNRS   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Desmosome; Epidermis; Hypotrichosis simplex of the scalp; Knockout mice; Psoriasis

Indexed keywords

CELL ADHESION MOLECULE; CELL MEMBRANE PROTEIN; CORNEODESMOSIN; CRE RECOMBINASE; CYTOKERATIN 14; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEGENERATION; CELL FUNCTION; CELL PROLIFERATION; CELL SURFACE; CELL ULTRASTRUCTURE; DESMOSOME; EPIDERMIS; FEMALE; GENE DELETION; GENE FUNCTION; GENE INDUCTION; HAIR FOLLICLE; KERATINOCYTE; KNOCKOUT MOUSE; LETHALITY; MALE; MECHANICAL STRESS; MOUSE; NEWBORN; NEWBORN DEATH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; SKIN PERMEABILITY;

ANIMALS; BLOTTING, WESTERN; DESMOSOMES; EPIDERMIS; FEMALE; GENE DELETION; GLYCOPROTEINS; HAIR FOLLICLE; HYPOTRICHOSIS; INTEGRASES; MALE; MICE; MICE, KNOCKOUT; MICE, NUDE; MICE, TRANSGENIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN TRANSPLANTATION;

MUS; MUS MUSCULUS;

EID: 69549096268     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.050302     Document Type: Article

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