Cationic liposomes containing soluble Leishmania antigens (SLA) plus CpG ODNs induce protection against murine model of leishmaniasis

Parasitology Research

Volumn 111, Issue 1, 2012, Pages 105-114

  Heravi Shargh, Vahid ^a   Jaafari, Mahmoud Reza ^a,b   Khamesipour, Ali ^c   Jalali, Seyed Amir ^a   Firouzmand, Hengameh ^a   Abbasi, Azam ^a   Badiee, Ali ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A ANTIBODY; INTERLEUKIN 4; LEISHMANIA VACCINE; LIPOSOME; SOLUBLE LEISHMANIA ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOPROPHYLAXIS; IMMUNOSTIMULATION; LEISHMANIA MAJOR; MOUSE; NONHUMAN; PARASITE LOAD; PRIORITY JOURNAL; SKIN LEISHMANIASIS; SPLEEN CELL; TREATMENT RESPONSE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; DRUG CARRIERS; FEMALE; FOOT; IMMUNOGLOBULIN G; INJECTIONS, SUBCUTANEOUS; INTERFERON-GAMMA; INTERLEUKIN-4; LEISHMANIA MAJOR; LEISHMANIASIS; LEISHMANIASIS VACCINES; LEUKOCYTES, MONONUCLEAR; LIPOSOMES; MICE; MICE, INBRED BALB C; OLIGODEOXYRIBONUCLEOTIDES; SPLEEN;

LEISHMANIA MAJOR; MURINAE; MUS;

EID: 84862773733     PISSN: 09320113     EISSN: 14321955     Source Type: Journal    
DOI: 10.1007/s00436-011-2806-5     Document Type: Article

References (56)

1. LC Afonso TM Scharton LQ Vieira M Wysocka G Trinchieri P Scott 1994 The adjuvant effect of interleukin-12 in a vaccine against Leishmania major Science 263 5144 235 237 7904381 10.1126/science.7904381 1:CAS:528:DyaK2cXhtVCnsrY%3D
2. F Afrin R Rajesh K Anam M Gopinath S Pal N Ali 2002 Characterization of Leishmania donovani antigens encapsulated in liposomes that induce protective immunity in BALB/c mice Infect Immun 70 12 6697 6706 12438344 10.1128/IAI.70.12.6697-6706.2002 1:CAS:528:DC%2BD38XptVyitbs%3D
3. A Badiee MR Jaafari A Khamesipour 2007 Leishmania major: immune response in BALB/c mice immunized with stress-inducible protein 1 encapsulated in liposomes Exp Parasitol 115 2 127 134 16979165 10.1016/j.exppara.2006.07.002 1:CAS:528:DC%2BD28Xht1Krt7jO
4. A Badiee MR Jaafari A Samiei D Soroush A Khamesipour 2008 Coencapsulation of CpG oligodeoxynucleotides with recombinant Leishmania major stress-inducible protein 1 in liposome enhances immune response and protection against leishmaniasis in immunized BALB/c mice Clin Vaccine Immunol 15 4 668 674 18235040 10.1128/CVI.00413-07
5. S Bhowmick R Ravindran N Ali 2007 Leishmanial antigens in liposomes promote protective immunity and provide immunotherapy against visceral leishmaniasis via polarized Th1 response Vaccine 25 35 6544 6556 17655984 10.1016/j.vaccine.2007.05.042 1:CAS:528:DC%2BD2sXovFOjurw%3D
6. W Chen W Yan L Huang 2008 A simple but effective cancer vaccine consisting of an antigen and a cationic lipid Cancer Immunol Immun 57 4 517 530 1:CAS:528:DC%2BD1cXhtV2isro%3D
7. GG Chikh S Kong MB Bally JC Meunier MP Schutze-Redelmeier 2001 Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells J Immunol 167 11 6462 6470 11714813 1:CAS:528:DC%2BD3MXovVCit7s%3D
8. RS Chu OS Targoni AM Krieg PV Lehmann CV Harding 1997 CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity J Exp Med 186 10 1623 1631 9362523 10.1084/jem.186.10.1623 1:CAS:528: DyaK2sXnsVeisbg%3D
9. RN Coler SG Reed 2005 Second-generation vaccines against leishmaniasis Trends Parasitol 21 5 244 249 15837614 10.1016/j.pt.2005.03.006 1:CAS:528:DC%2BD2MXjtlWrtLc%3D
10. SL Croft S Sundar AH Fairlamb 2006 Drug resistance in leishmaniasis Clin Microbiol Rev 19 1 111 126 16418526 10.1128/CMR.19.1.111-126.2006 1:CAS:528:DC%2BD28XhsFGjtbk%3D
11. MC De Oliveira V Boutet E Fattal D Boquet J-M Grognet P Couvreur J-R Deverre 2000 Improvement of in vivo stability of phosphodiester oligonucleotide using anionic liposomes in mice Life Sci 67 13 1625 1637 10983856 10.1016/S0024-3205(00)00745-1
12. FJ Dumont 2002 Modulation of Th1 and Th2 responses for immunotherapy Expert Opin Ther Pat 12 3 341 367 10.1517/13543776.12.3.341 1:CAS:528: DC%2BD38XitFSjurg%3D
13. A Firooz A Khamesipour MH Ghoorchi M Nassiri-Kashani SE Eskandari A Khatami B Hooshmand F Gorouhi M Rashighi-Firoozabadi Y Dowlati 2006 Imiquimod in combination with meglumine antimoniate for cutaneous leishmaniasis: a randomized assessor-blind controlled trial Arch Dermatol 142 12 1575 1579 17178983 10.1001/archderm.142.12.1575 1:CAS:528:DC%2BD2sXls1Ghsg%3D%3D
14. IM Hafez N Maurer PR Cullis 2001 On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids Gene Ther 8 15 1188 1196 11509950 10.1038/sj.gt.3301506 1:CAS:528:DC%2BD3MXlvVSlsbY%3D
15. E Handman 2001 Leishmaniasis: current status of vaccine development Clin Microbiol Rev 14 2 229 243 11292637 10.1128/CMR.14.2.229-243.2001 1:CAS:528:DC%2BD3MXjtlKhtrk%3D
16. H Hemmi O Takeuchi T Kawai T Kaisho S Sato H Sanjo M Matsumoto K Hoshino H Wagner K Takeda S Akira 2000 A Toll-like receptor recognizes bacterial DNA Nature 408 6813 740 745 11130078 10.1038/35047123 1:CAS:528:DC%2BD3cXptVCqsL0%3D
17. D Hoekstra J Rejman L Wasungu F Shi I Zuhorn 2007 Gene delivery by cationic lipids: in and out of an endosome Biochem Soc T 035 1 68 71 10.1042/BST0350068 1:CAS:528:DC%2BD2sXit1Oktrg%3D
18. R Ignatius K Mahnke M Rivera K Hong F Isdell RM Steinman M Pope L Stamatatos 2000 Presentation of proteins encapsulated in sterically stabilized liposomes by dendritic cells initiates CD8+ T-cell responses in vivo Blood 96 10 3505 3513 11071648 1:CAS:528:DC%2BD3cXotFKku70%3D
19. MR Jaafari A Badiee A Khamesipour A Samiei D Soroush MT Kheiri F Barkhordari WR McMaster F Mahboudi 2007 The role of CpG ODN in enhancement of immune response and protection in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63) encapsulated in cationic liposome Vaccine 25 32 6107 6117 17629372 10.1016/j.vaccine.2007.05.009 1:CAS:528:DC%2BD2sXotVGlt7g%3D
20. X Jiao RY-H Wang Q Qiu HJ Alter JW-K Shih 2004 Enhanced hepatitis C virus NS3 specific Th1 immune responses induced by co-delivery of protein antigen and CpG with cationic liposomes J Gen Virol 85 6 1545 1553 15166438 10.1099/vir.0.79896-0 1:CAS:528:DC%2BD2cXltlGhtro%3D
21. PP Karmali A Chaudhuri 2007 Cationic liposomes as non-viral carriers of gene medicines: resolved issues, open questions, and future promises Med Res Rev 27 5 696 722 17022036 10.1002/med.20090 1:CAS:528:DC%2BD2sXhtFGgtL%2FO
22. H Keshavarz Valian L Khoshabe Abdollah Kenedy M Nateghi Rostami A Miramin Mohammadi A Khamesipour 2008 Role of Mycobacterium vaccae in the protection induced by first generation Leishmania vaccine against murine model of leishmaniasis Parasitol Res 103 1 21 28 18317808 10.1007/s00436-008-0921-8
23. EA Khalil AM El Hassan EE Zijlstra MM Mukhtar HW Ghalib B Musa ME Ibrahim AA Kamil M Elsheikh A Babiker F Modabber 2000 Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan Lancet 356 9241 1565 1569 11075771 10.1016/S0140-6736(00)03128-7 1:CAS:528:DC%2BD3cXot12lsbs%3D
24. A Khamesipour S Rafati N Davoudi F Maboudi F Modabber 2006 Leishmaniasis vaccine candidates for development: a global overview Indian J Med Res 123 3 423 438 16778321
25. DM Klinman 2004 Use of CpG oligodeoxynucleotides as immunoprotective agents Expert Opin Biol Ther 4 6 937 946 15174975 10.1517/14712598.4.6.937 1:CAS:528:DC%2BD2cXksVaqtLs%3D
26. DM Klinman D Currie I Gursel D Verthelyi 2004 Use of CpG oligodeoxynucleotides as immune adjuvants Immunol Rev 199 1 201 216 15233736 10.1111/j.0105-2896.2004.00148.x 1:CAS:528:DC%2BD2cXltFygsLY%3D
27. AM Krieg 2000 The role of CpG motifs in innate immunity Curr Opin Immunol 12 1 35 43 10679406 10.1016/S0952-7915(99)00048-5 1:CAS:528: DC%2BD3cXhsVOktbc%3D
28. AM Krieg 2002 CpG motifs in bacterial DNA and their immune effects Annu Rev Immunol 20 1 709 760 11861616 10.1146/annurev.immunol.20.100301.064842 1:CAS:528:DC%2BD38XjtlWgtbw%3D
29. AA Levin 1999 A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides Biochim Biophys Acta 1489 1 69 84 10806998 1:CAS:528:DyaK1MXns1Sltbo%3D
30. WM Li WH Dragowska MB Bally M-P Schutze-Redelmeier 2003 Effective induction of CD8+ T-cell response using CpG oligodeoxynucleotides and HER-2/neu-derived peptide co-encapsulated in liposomes Vaccine 21 23 3319 3329 12804863 10.1016/S0264-410X(03)00172-5 1:CAS:528:DC%2BD3sXksVyqtrc%3D
31. Manuel S, Ramirez L, Pineda MA, Gonzalez V, Entringer PF, de Oliveira CI, Nascimento IP, Souza AP, Corvo L, Alonso C, Bonay P, Brodskyn C, Barral A, Barral-Netto M, Iborra S (2009) Searching genes encoding Leishmania antigens for diagnosis and protection. Scholarly Res Exchange 2009
32. EA Marques-da-Silva EA Coelho DC Gomes MC Vilela CZ Masioli CA Tavares AP Fernandes LC Afonso SA Rezende 2005 Intramuscular immunization with p36(LACK) DNA vaccine induces IFN-gamma production but does not protect BALB/c mice against Leishmania chagasi intravenous challenge Parasitol Res 98 1 67 74 16261353 10.1007/s00436-005-0008-8
33. S Mazumder R Ravindran A Banerjee N Ali 2007 Non-coding pDNA bearing immunostimulatory sequences co-entrapped with leishmanial antigens in cationic liposomes elicits almost complete protection against experimental visceral leishmaniasis in BALB/c mice Vaccine 25 52 8771 8781 18031874 10.1016/j.vaccine.2007.10.028 1:CAS:528:DC%2BD2sXhsVWjt7vM
34. PC Melby 2002 Vaccination against cutaneous leishmaniasis: current status Am J Clin Dermatol 3 8 557 570 12358557 10.2165/00128071-200203080-00006
35. F Modabber 1995 Vaccines against leishmaniasis Ann Trop Med Parasitol 89 Suppl 1 83 88 8745930 1:CAS:528:DyaK28XjvFygsbc%3D
36. AZ Momeni T Jalayer M Emamjomeh A Khamesipour F Zicker RL Ghassemi Y Dowlati I Sharifi M Aminjavaheri A Shafiei MH Alimohammadian R Hashemi-Fesharki K Nasseri T Godal PG Smith F Modabber 1999 A randomised, double-blind, controlled trial of a killed L. major vaccine plus BCG against zoonotic cutaneous leishmaniasis in Iran Vaccine 17 5 466 472 10073725 10.1016/S0264-410X(98)00220-5 1:STN:280:DyaK1M7ntFOgsQ%3D%3D
37. AM Musa EA Khalil FA Mahgoub SH Elgawi F Modabber AE Elkadaru MH Aboud S Noazin HW Ghalib AM El-Hassan 2008 Immunochemotherapy of persistent post-kala-azar dermal leishmaniasis: a novel approach to treatment Trans R Soc Trop Med Hyg 102 1 58 63 17963805 10.1016/j.trstmh.2007.08.006 1:CAS:528:DC%2BD1cXitFKjt7o%3D
38. T Nakanishi J Kunisawa A Hayashi Y Tsutsumi K Kubo S Nakagawa H Fujiwara T Hamaoka T Mayumi 1997 Positively charged liposome functions as an efficient immunoadjuvant in inducing immune responses to soluble proteins Biochem Biophys Res Co 240 3 793 797 10.1006/bbrc.1997.7749 1:CAS:528:DyaK2sXnslGmsLk%3D
39. T Nakanishi J Kunisawa A Hayashi Y Tsutsumi K Kubo S Nakagawa M Nakanishi K Tanaka T Mayumi 1999 Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins J Control Release 61 1-2 233 240 10469918 10.1016/S0168-3659(99)00097-8 1:CAS:528:DyaK1MXlsFOrsrY%3D
40. S Noazin F Modabber A Khamesipour PG Smith LH Moulton K Nasseri I Sharifi EA Khalil ID Bernal CM Antunes MP Kieny M Tanner 2008 First generation leishmaniasis vaccines: a review of field efficacy trials Vaccine 26 52 6759 6767 18950671 10.1016/j.vaccine.2008.09.085 1:CAS:528:DC%2BD1cXhsVertrzP
41. S Noazin A Khamesipour LH Moulton M Tanner K Nasseri F Modabber I Sharifi EAG Khalil IDV Bernal CMF Antunes PG Smith 2009 Efficacy of killed whole-parasite vaccines in the prevention of leishmaniasis-a meta-analysis Vaccine 27 35 4747 4753 19540273 10.1016/j.vaccine.2009.05.084 1:CAS:528:DC%2BD1MXos12qtL0%3D
42. M Rao CR Alving 2000 Delivery of lipids and liposomal proteins to the cytoplasm and Golgi of antigen-presenting cells Adv Drug Deliver Rev 41 2 171 188 10.1016/S0169-409X(99)00064-2 1:CAS:528:DC%2BD3cXhsVWqsLY%3D
43. EG Rhee S Mendez JA Shah Wu C-Y JR Kirman TN Turon DF Davey H Davis DM Klinman RN Coler DL Sacks RA Seder 2002 Vaccination with heat-killed Leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against Leishmania major infection J Exp Med 195 12 1565 1573 12070284 10.1084/jem.20020147 1:CAS:528:DC%2BD38XkslWht74%3D
44. DO Santos CE Coutinho MF Madeira CG Bottino RT Vieira SB Nascimento A Bernardino SC Bourguignon S Corte-Real RT Pinho CR Rodrigues HC Castro 2008 Leishmaniasis treatment-a challenge that remains: a review Parasitol Res 103 1 1 10 18389282 10.1007/s00436-008-0943-2
45. P Scott E Pearce P Natovitz A Sher 1987 Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes J Immunol 139 1 221 227 3495599 1:STN:280:DyaL2s3isVWmug%3D%3D
46. I Sharifi AR FeKri MR Aflatonian A Khamesipour A Nadim MR Mousavi AZ Momeni Y Dowlati T Godal F Zicker PG Smith F Modabber 1998 Randomised vaccine trial of single dose of killed Leishmania major plus BCG against anthroponotic cutaneous leishmaniasis in Bam, Iran Lancet 351 9115 1540 1543 10326536 10.1016/S0140-6736(98)09552-X 1:STN:280:DyaK1M3lvVeqtw%3D%3D
47. Y Suzuki D Wakita K Chamoto Y Narita T Tsuji T Takeshima H Gyobu Y Kawarada S Kondo S Akira H Katoh H Ikeda T Nishimura 2004 Liposome-encapsulated CpG oligodeoxynucleotides as a potent adjuvant for inducing type 1 innate immunity Cancer Res 64 23 8754 8760 15574787 10.1158/0008-5472.CAN-04-1691 1:CAS:528:DC%2BD2cXhtVCjs7vP
48. M Tafaghodi A Khamesipour MR Jaafari 2010 Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN Parasitol Res 108 5 1265 1273 21125294 10.1007/s00436-010- 2176-4
49. C Taswell 1981 Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis J Immunol 126 4 1614 1619 7009746 1:STN:280:DyaL3M7ktlGhsA%3D%3D
50. DP Vangasseri Z Cui W Chen DA Hokey LD Falo L Huang 2006 Immunostimulation of dendritic cells by cationic liposomes Mol Membr Biol 23 5 385 395 17060156 10.1080/09687860600790537 1:CAS:528:DC%2BD28XhtlCgurfE
51. L Wasungu D Hoekstra 2006 Cationic lipids, lipoplexes and intracellular delivery of genes J Control Release 116 2 255 264 16914222 10.1016/j.jconrel. 2006.06.024 1:CAS:528:DC%2BD28Xht12jtL3K
52. RD Weeratna CL Brazolot Millan MJ McCluskie HL Davis 2001 CpG ODN can re-direct the Th bias of established Th2 immune responses in adult and young mice FEMS Immunol Med Microbiol 32 1 65 71 11750224 10.1111/j.1574-695X.2001. tb00535.x 1:CAS:528:DC%2BD3MXpt1amt70%3D
53. KD Wilson SD de Jong YK Tam 2009 Lipid-based delivery of CpG oligonucleotides enhances immunotherapeutic efficacy Adv Drug Deliver Rev 61 3 233 242 10.1016/j.addr.2008.12.014 1:CAS:528:DC%2BD1MXjtFKltbc%3D
54. W Yan W Chen L Huang 2007 Mechanism of adjuvant activity of cationic liposome: phosphorylation of a MAP kinase, ERK and induction of chemokines Mol Immunol 44 15 3672 3681 17521728 10.1016/j.molimm.2007.04.009 1:CAS:528:DC%2BD2sXmtVSks7Y%3D
55. J Zabner AJ Fasbender T Moninger KA Poellinger MJ Welsh 1995 Cellular and molecular barriers to gene transfer by a cationic lipid J Biol Chem 270 32 18997 19007 7642560 10.1074/jbc.270.32.18997 1:CAS:528:DyaK2MXnsVOju7s%3D
56. YM Zhang M Rusckowski N Liu C Liu DJ Hnatowich 2001 Cationic liposomes enhance cellular/nuclear localization of 99mTc-antisense oligonucleotides in target tumor cells Cancer Biother Radiopharm 16 5 411 419 11776758 10.1089/108497801753354311 1:CAS:528:DC%2BD38Xkt1WmtQ%3D%3D