메뉴 건너뛰기




Volumn 61, Issue 7, 2012, Pages 1005-1018

Regulation of autologous immunity to the mouse 5T4 oncofoetal antigen: Implications for immunotherapy

Author keywords

5T4 oncofoetal antigen; Immunotherapy; T cell epitopes; T cell repertoire; T regulatory cells; Vaccine

Indexed keywords

CANCER VACCINE; EPITOPE; FOLATE RECEPTOR; FOLATE RECEPTOR 4; FOLIC ACID ANTAGONIST; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; ONCOFETAL ANTIGEN; ONCOFETAL ANTIGEN 5T4; REPLICATION DEFECTIVE ADENOVIRUS ENCODING MOUSE 5T4 VACCINE; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 84862773091     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-011-1167-3     Document Type: Article
Times cited : (9)

References (51)
  • 1
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • 10.1038/nm1100 15340416 10.1038/nm1100 1:CAS:528:DC%2BD2cXntFSktL0%3D
    • SA Rosenberg JC Yang NP Restifo 2004 Cancer immunotherapy: moving beyond current vaccines Nat Med 10 9 909 915 10.1038/nm1100 15340416 10.1038/nm1100 1:CAS:528:DC%2BD2cXntFSktL0%3D
    • (2004) Nat Med , vol.10 , Issue.9 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 2
    • 67650744372 scopus 로고    scopus 로고
    • Immune therapy for cancer
    • 10.1146/annurev.immunol.021908.132544 19007331 10.1146/annurev.immunol. 021908.132544 1:CAS:528:DC%2BD1MXlsFSlsbo%3D
    • M Dougan G Dranoff 2009 Immune therapy for cancer Annu Rev Immunol 27 83 117 10.1146/annurev.immunol.021908.132544 19007331 10.1146/annurev.immunol. 021908.132544 1:CAS:528:DC%2BD1MXlsFSlsbo%3D
    • (2009) Annu Rev Immunol , vol.27 , pp. 83-117
    • Dougan, M.1    Dranoff, G.2
  • 3
    • 0023818391 scopus 로고
    • A 72 kD trophoblast glycoprotein defined by a monoclonal antibody
    • 3355761 10.1038/bjc.1988.53 1:CAS:528:DyaL1cXitVarsbc%3D
    • N Hole PL Stern 1988 A 72 kD trophoblast glycoprotein defined by a monoclonal antibody Br J Cancer 57 3 239 246 3355761 10.1038/bjc.1988.53 1:CAS:528:DyaL1cXitVarsbc%3D
    • (1988) Br J Cancer , vol.57 , Issue.3 , pp. 239-246
    • Hole, N.1    Stern, P.L.2
  • 4
    • 0025060715 scopus 로고
    • Isolation and characterization of 5T4, a tumour-associated antigen
    • 2298503 10.1002/ijc.2910450132 1:STN:280:DyaK3c7ivFCiug%3D%3D
    • N Hole PL Stern 1990 Isolation and characterization of 5T4, a tumour-associated antigen Int J Cancer 45 1 179 184 2298503 10.1002/ijc. 2910450132 1:STN:280:DyaK3c7ivFCiug%3D%3D
    • (1990) Int J Cancer , vol.45 , Issue.1 , pp. 179-184
    • Hole, N.1    Stern, P.L.2
  • 5
    • 0025109257 scopus 로고
    • Immunohistological distribution of 5T4 antigen in normal and malignant tissues
    • 2404511 10.1038/bjc.1990.20 1:STN:280:DyaK3c7it1GrtQ%3D%3D
    • PJ Southall GM Boxer KD Bagshawe N Hole M Bromley PL Stern 1990 Immunohistological distribution of 5T4 antigen in normal and malignant tissues Br J Cancer 61 1 89 95 2404511 10.1038/bjc.1990.20 1:STN:280: DyaK3c7it1GrtQ%3D%3D
    • (1990) Br J Cancer , vol.61 , Issue.1 , pp. 89-95
    • Southall, P.J.1    Boxer, G.M.2    Bagshawe, K.D.3    Hole, N.4    Bromley, M.5    Stern, P.L.6
  • 6
    • 0036326404 scopus 로고    scopus 로고
    • Oncofetal antigen 5T4 expression as a prognostic factor in patients with gastric cancer
    • 12168897 1:CAS:528:DC%2BD38XmsFWrsr4%3D
    • H Naganuma K Kono Y Mori S Takayoshi PL Stern K Tasaka Y Matsumoto 2002 Oncofetal antigen 5T4 expression as a prognostic factor in patients with gastric cancer Anticancer Res 22 2B 1033 1038 12168897 1:CAS:528:DC%2BD38XmsFWrsr4%3D
    • (2002) Anticancer Res , vol.22 , Issue.2 B , pp. 1033-1038
    • Naganuma, H.1    Kono, K.2    Mori, Y.3    Takayoshi, S.4    Stern, P.L.5    Tasaka, K.6    Matsumoto, Y.7
  • 7
    • 0028324131 scopus 로고
    • Prognostic significance of 5T4 oncofetal antigen expression in colorectal carcinoma
    • 8180020 10.1038/bjc.1994.173 1:STN:280:DyaK2c3jsFCntg%3D%3D
    • T Starzynska PJ Marsh PF Schofield SA Roberts KA Myers PL Stern 1994 Prognostic significance of 5T4 oncofetal antigen expression in colorectal carcinoma Br J Cancer 69 5 899 902 8180020 10.1038/bjc.1994.173 1:STN:280:DyaK2c3jsFCntg%3D%3D
    • (1994) Br J Cancer , vol.69 , Issue.5 , pp. 899-902
    • Starzynska, T.1    Marsh, P.J.2    Schofield, P.F.3    Roberts, S.A.4    Myers, K.A.5    Stern, P.L.6
  • 9
    • 0036290427 scopus 로고    scopus 로고
    • 5T4 interacts with TIP-2/GIPC, a PDZ protein, with implications for metastasis
    • 10.1006/bbrc.2001.6288 11798178 10.1006/bbrc.2001.6288 1:CAS:528:DC%2BD38XksVyqsw%3D%3D
    • A Awan MR Lucic DM Shaw F Sheppard C Westwater SA Lyons PL Stern 2002 5T4 interacts with TIP-2/GIPC, a PDZ protein, with implications for metastasis Biochem Biophys Res Commun 290 3 1030 1036 10.1006/bbrc.2001.6288 11798178 10.1006/bbrc.2001.6288 1:CAS:528:DC%2BD38XksVyqsw%3D%3D
    • (2002) Biochem Biophys Res Commun , vol.290 , Issue.3 , pp. 1030-1036
    • Awan, A.1    Lucic, M.R.2    Shaw, D.M.3    Sheppard, F.4    Westwater, C.5    Lyons, S.A.6    Stern, P.L.7
  • 10
    • 0029903794 scopus 로고    scopus 로고
    • Metastasis-associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells
    • 10.1002/(SICI)1097-0215(19960927)68:1<84::AID-IJC15>3.0.CO;2-6 8895545 10.1002/(SICI)1097-0215(19960927)68:1<84::AID-IJC15>3.0.CO;2-6 1:CAS:528:DyaK28XmsFyhurc%3D
    • CJ Carsberg KA Myers PL Stern 1996 Metastasis-associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells Int J Cancer 68 1 84 92 10.1002/(SICI)1097-0215(19960927)68:1<84::AID- IJC15>3.0.CO;2-6 8895545 10.1002/(SICI)1097-0215(19960927)68:1<84::AID- IJC15>3.0.CO;2-6 1:CAS:528:DyaK28XmsFyhurc%3D
    • (1996) Int J Cancer , vol.68 , Issue.1 , pp. 84-92
    • Carsberg, C.J.1    Myers, K.A.2    Stern, P.L.3
  • 12
    • 33847205332 scopus 로고    scopus 로고
    • A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma
    • 10.1038/sj.bjc.6603567 17285137 10.1038/sj.bjc.6603567 1:CAS:528:DC%2BD2sXhvV2jsbY%3D
    • DM Shaw NB Connolly PM Patel S Kilany G Hedlund O Nordle G Forsberg J Zweit PL Stern RE Hawkins 2007 A phase II study of a 5T4 oncofoetal antigen tumour-targeted superantigen (ABR-214936) therapy in patients with advanced renal cell carcinoma Br J Cancer 96 4 567 574 10.1038/sj.bjc.6603567 17285137 10.1038/sj.bjc.6603567 1:CAS:528:DC%2BD2sXhvV2jsbY%3D
    • (2007) Br J Cancer , vol.96 , Issue.4 , pp. 567-574
    • Shaw, D.M.1    Connolly, N.B.2    Patel, P.M.3    Kilany, S.4    Hedlund, G.5    Nordle, O.6    Forsberg, G.7    Zweit, J.8    Stern, P.L.9    Hawkins, R.E.10
  • 14
    • 27144440353 scopus 로고    scopus 로고
    • Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: A potential target for T-cell-based immunotherapy
    • 10.1038/sj.bjc.6602776 16222313 10.1038/sj.bjc.6602776 1:CAS:528:DC%2BD2MXhtV2kt7rE
    • RW Griffiths DE Gilham A Dangoor V Ramani NW Clarke PL Stern RE Hawkins 2005 Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: a potential target for T-cell-based immunotherapy Br J Cancer 93 6 670 677 10.1038/sj.bjc.6602776 16222313 10.1038/sj.bjc.6602776 1:CAS:528: DC%2BD2MXhtV2kt7rE
    • (2005) Br J Cancer , vol.93 , Issue.6 , pp. 670-677
    • Griffiths, R.W.1    Gilham, D.E.2    Dangoor, A.3    Ramani, V.4    Clarke, N.W.5    Stern, P.L.6    Hawkins, R.E.7
  • 15
    • 20944439742 scopus 로고    scopus 로고
    • The role of extracellular spacer regions in the optimal design of chimeric immune receptors: Evaluation of four different scFvs and antigens
    • 00002371-200505000-00005 15838376 10.1097/01.cji.0000161397.96582.59 1:CAS:528:DC%2BD2MXjtlKlurc%3D
    • RD Guest RE Hawkins N Kirillova EJ Cheadle J Arnold A O'Neill J Irlam KA Chester JT Kemshead DM Shaw MJ Embleton PL Stern DE Gilham 2005 The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens J Immunother 28 3 203 211 00002371-200505000-00005 15838376 10.1097/01.cji.0000161397.96582.59 1:CAS:528:DC%2BD2MXjtlKlurc%3D
    • (2005) J Immunother , vol.28 , Issue.3 , pp. 203-211
    • Guest, R.D.1    Hawkins, R.E.2    Kirillova, N.3    Cheadle, E.J.4    Arnold, J.5    O'Neill, A.6    Irlam, J.7    Chester, K.A.8    Kemshead, J.T.9    Shaw, D.M.10    Embleton, M.J.11    Stern, P.L.12    Gilham, D.E.13
  • 16
    • 78149282337 scopus 로고    scopus 로고
    • Cross-trial analysis of immunologic and clinical data resulting from phase i and II trials of MVA-5T4 (TroVax) in colorectal, renal, and prostate cancer patients
    • 10.1097/CJI.0b013e3181f5dac7 20948436 10.1097/CJI.0b013e3181f5dac7 1:CAS:528:DC%2BC3cXhtlGkurbE
    • R Harrop W Shingler M Kelleher J de Belin P Treasure 2010 Cross-trial analysis of immunologic and clinical data resulting from phase I and II trials of MVA-5T4 (TroVax) in colorectal, renal, and prostate cancer patients J Immunother 33 9 999 1005 10.1097/CJI.0b013e3181f5dac7 20948436 10.1097/CJI.0b013e3181f5dac7 1:CAS:528:DC%2BC3cXhtlGkurbE
    • (2010) J Immunother , vol.33 , Issue.9 , pp. 999-1005
    • Harrop, R.1    Shingler, W.2    Kelleher, M.3    De Belin, J.4    Treasure, P.5
  • 19
    • 1842848097 scopus 로고    scopus 로고
    • Attenuated recombinant vaccinia virus expressing oncofetal antigen (tumor-associated antigen) 5T4 induces active therapy of established tumors
    • 12481437 1:CAS:528:DC%2BD3sXmtFamtw%3D%3D
    • K Mulryan MG Ryan KA Myers D Shaw W Wang SM Kingsman PL Stern MW Carroll 2002 Attenuated recombinant vaccinia virus expressing oncofetal antigen (tumor-associated antigen) 5T4 induces active therapy of established tumors Mol Cancer Ther 1 12 1129 1137 12481437 1:CAS:528:DC%2BD3sXmtFamtw%3D%3D
    • (2002) Mol Cancer Ther , vol.1 , Issue.12 , pp. 1129-1137
    • Mulryan, K.1    Ryan, M.G.2    Myers, K.A.3    Shaw, D.4    Wang, W.5    Kingsman, S.M.6    Stern, P.L.7    Carroll, M.W.8
  • 20
    • 0036897080 scopus 로고    scopus 로고
    • Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity
    • 12460911 1:CAS:528:DC%2BD38XpsVahsLk%3D
    • JW Greiner H Zeytin MR Anver J Schlom 2002 Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity Cancer Res 62 23 6944 6951 12460911 1:CAS:528:DC%2BD38XpsVahsLk%3D
    • (2002) Cancer Res , vol.62 , Issue.23 , pp. 6944-6951
    • Greiner, J.W.1    Zeytin, H.2    Anver, M.R.3    Schlom, J.4
  • 21
    • 0037989845 scopus 로고    scopus 로고
    • Vaccine therapy of established tumors in the absence of autoimmunity
    • 12738742 1:CAS:528:DC%2BD3sXjsFeitLs%3D
    • JW Hodge DW Grosenbach WM Aarts DJ Poole J Schlom 2003 Vaccine therapy of established tumors in the absence of autoimmunity Clin Cancer Res 9 5 1837 1849 12738742 1:CAS:528:DC%2BD3sXjsFeitLs%3D
    • (2003) Clin Cancer Res , vol.9 , Issue.5 , pp. 1837-1849
    • Hodge, J.W.1    Grosenbach, D.W.2    Aarts, W.M.3    Poole, D.J.4    Schlom, J.5
  • 22
    • 45849098275 scopus 로고    scopus 로고
    • Danger signals and nonself entity of tumor antigen are both required for eliciting effective immune responses against HER-2/neu positive mammary carcinoma: Implications for vaccine design
    • 10.1007/s00262-008-0475-8 18278493 10.1007/s00262-008-0475-8 1:CAS:528:DC%2BD1cXnsFeis7s%3D
    • M Kmieciak JK Morales J Morales E Bolesta M Grimes MH Manjili 2008 Danger signals and nonself entity of tumor antigen are both required for eliciting effective immune responses against HER-2/neu positive mammary carcinoma: implications for vaccine design Cancer Immunol Immunother 57 9 1391 1398 10.1007/s00262-008-0475-8 18278493 10.1007/s00262-008-0475-8 1:CAS:528:DC%2BD1cXnsFeis7s%3D
    • (2008) Cancer Immunol Immunother , vol.57 , Issue.9 , pp. 1391-1398
    • Kmieciak, M.1    Morales, J.K.2    Morales, J.3    Bolesta, E.4    Grimes, M.5    Manjili, M.H.6
  • 24
    • 79953756264 scopus 로고    scopus 로고
    • Modified vaccinia Ankara expressing survivin combined with gemcitabine generates specific antitumor effects in a murine pancreatic carcinoma model
    • 10.1007/s00262-010-0923-0 20960189 10.1007/s00262-010-0923-0 1:CAS:528:DC%2BC3MXht12gtrs%3D
    • H Ishizaki ER Manuel GY Song T Srivastava S Sun DJ Diamond JD Ellenhorn 2011 Modified vaccinia Ankara expressing survivin combined with gemcitabine generates specific antitumor effects in a murine pancreatic carcinoma model Cancer Immunol Immunother 60 1 99 109 10.1007/s00262-010-0923-0 20960189 10.1007/s00262-010-0923-0 1:CAS:528:DC%2BC3MXht12gtrs%3D
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.1 , pp. 99-109
    • Ishizaki, H.1    Manuel, E.R.2    Song, G.Y.3    Srivastava, T.4    Sun, S.5    Diamond, D.J.6    Ellenhorn, J.D.7
  • 26
    • 34047266237 scopus 로고    scopus 로고
    • Therapy of established tumors in a novel murine model transgenic for human carcinoembryonic antigen and HLA-A2 with a combination of anti-idiotype vaccine and CTL peptides of carcinoembryonic antigen
    • 10.1158/0008-5472.CAN-06-3045 17363612 10.1158/0008-5472.CAN-06-3045 1:CAS:528:DC%2BD2sXivV2ntr4%3D
    • A Saha SK Chatterjee KA Foon E Celis M Bhattacharya-Chatterjee 2007 Therapy of established tumors in a novel murine model transgenic for human carcinoembryonic antigen and HLA-A2 with a combination of anti-idiotype vaccine and CTL peptides of carcinoembryonic antigen Cancer Res 67 6 2881 2892 10.1158/0008-5472.CAN-06-3045 17363612 10.1158/0008-5472.CAN-06-3045 1:CAS:528:DC%2BD2sXivV2ntr4%3D
    • (2007) Cancer Res , vol.67 , Issue.6 , pp. 2881-2892
    • Saha, A.1    Chatterjee, S.K.2    Foon, K.A.3    Celis, E.4    Bhattacharya-Chatterjee, M.5
  • 27
    • 77954096689 scopus 로고    scopus 로고
    • IL-6: Regulator of Treg/Th17 balance
    • 20583029 10.1002/eji.201040391 1:CAS:528:DC%2BC3cXotVOkurc%3D
    • A Kimura T Kishimoto 2010 IL-6: regulator of Treg/Th17 balance Eur J Immunol 40 7 1830 1835 20583029 10.1002/eji.201040391 1:CAS:528: DC%2BC3cXotVOkurc%3D
    • (2010) Eur J Immunol , vol.40 , Issue.7 , pp. 1830-1835
    • Kimura, A.1    Kishimoto, T.2
  • 29
    • 34447643405 scopus 로고    scopus 로고
    • Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor
    • 17613255 10.1016/j.immuni.2007.04.017 1:CAS:528:DC%2BD2sXosFeqt74%3D
    • T Yamaguchi K Hirota K Nagahama K Ohkawa T Takahashi T Nomura S Sakaguchi 2007 Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor Immunity 27 1 145 159 17613255 10.1016/j.immuni.2007.04.017 1:CAS:528:DC%2BD2sXosFeqt74%3D
    • (2007) Immunity , vol.27 , Issue.1 , pp. 145-159
    • Yamaguchi, T.1    Hirota, K.2    Nagahama, K.3    Ohkawa, K.4    Takahashi, T.5    Nomura, T.6    Sakaguchi, S.7
  • 30
    • 34547778867 scopus 로고    scopus 로고
    • E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells
    • 17507657 10.1091/mbc.E06-09-0875 1:CAS:528:DC%2BD2sXovFalurw%3D
    • HL Spencer AM Eastham CL Merry TD Southgate F Perez-Campo F Soncin S Ritson R Kemler PL Stern CM Ward 2007 E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells Mol Biol Cell 18 8 2838 2851 17507657 10.1091/mbc.E06-09-0875 1:CAS:528:DC%2BD2sXovFalurw%3D
    • (2007) Mol Biol Cell , vol.18 , Issue.8 , pp. 2838-2851
    • Spencer, H.L.1    Eastham, A.M.2    Merry, C.L.3    Southgate, T.D.4    Perez-Campo, F.5    Soncin, F.6    Ritson, S.7    Kemler, R.8    Stern, P.L.9    Ward, C.M.10
  • 31
    • 0037103839 scopus 로고    scopus 로고
    • Characterization of the murine 5T4 oncofoetal antigen: A target for immunotherapy in cancer
    • 10.1042/BJ20020104 12003637 1:CAS:528:DC%2BD3sXptFOhtb0%3D
    • AM Woods WW Wang DM Shaw CM Ward MW Carroll BR Rees PL Stern 2002 Characterization of the murine 5T4 oncofoetal antigen: a target for immunotherapy in cancer Biochem J 366 Pt 1 353 365 10.1042/BJ20020104 12003637 1:CAS:528:DC%2BD3sXptFOhtb0%3D
    • (2002) Biochem J , vol.366 , Issue.PART 1 , pp. 353-365
    • Woods, A.M.1    Wang, W.W.2    Shaw, D.M.3    Ward, C.M.4    Carroll, M.W.5    Rees, B.R.6    Stern, P.L.7
  • 32
    • 33751551485 scopus 로고    scopus 로고
    • Immunotherapy success in prophylaxis cannot predict therapy: Prime-boost vaccination against the 5T4 oncofoetal antigen
    • 10.1007/s00262-006-0179-x 16758205 10.1007/s00262-006-0179-x 1:CAS:528:DC%2BD28Xht1Gnu7vJ
    • S Ali K Mulryan T Taher PL Stern 2007 Immunotherapy success in prophylaxis cannot predict therapy: prime-boost vaccination against the 5T4 oncofoetal antigen Cancer Immunol Immunother 56 2 165 180 10.1007/s00262-006- 0179-x 16758205 10.1007/s00262-006-0179-x 1:CAS:528:DC%2BD28Xht1Gnu7vJ
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.2 , pp. 165-180
    • Ali, S.1    Mulryan, K.2    Taher, T.3    Stern, P.L.4
  • 33
    • 22244468657 scopus 로고    scopus 로고
    • Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia
    • 15977177 10.1002/dvdy.20482 1:CAS:528:DC%2BD2MXnvVWrur4%3D
    • KM Barrow CM Ward J Rutter S Ali PL Stern 2005 Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia Dev Dyn 233 4 1535 1545 15977177 10.1002/dvdy.20482 1:CAS:528:DC%2BD2MXnvVWrur4%3D
    • (2005) Dev Dyn , vol.233 , Issue.4 , pp. 1535-1545
    • Barrow, K.M.1    Ward, C.M.2    Rutter, J.3    Ali, S.4    Stern, P.L.5
  • 35
    • 0032980503 scopus 로고    scopus 로고
    • Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4(+) T lymphocytes
    • 10077623 10.1073/pnas.96.6.2982 1:CAS:528:DyaK1MXhvFyksb4%3D
    • WW Overwijk DS Lee DR Surman KR Irvine CE Touloukian CC Chan MW Carroll B Moss SA Rosenberg NP Restifo 1999 Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes Proc Natl Acad Sci U S A 96 6 2982 2987 10077623 10.1073/pnas.96.6.2982 1:CAS:528:DyaK1MXhvFyksb4%3D
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.6 , pp. 2982-2987
    • Overwijk, W.W.1    Lee, D.S.2    Surman, D.R.3    Irvine, K.R.4    Touloukian, C.E.5    Chan, C.C.6    Carroll, M.W.7    Moss, B.8    Rosenberg, S.A.9    Restifo, N.P.10
  • 36
    • 68449088814 scopus 로고    scopus 로고
    • High-avidity autoreactive CD4+ T cells induce host CTL, overcome T(regs) and mediate tumor destruction
    • 10.1097/CJI.0b013e3181ab1824 19561540 10.1097/CJI.0b013e3181ab1824
    • AG Brandmaier WW Leitner SP Ha J Sidney NP Restifo CE Touloukian 2009 High-avidity autoreactive CD4+ T cells induce host CTL, overcome T(regs) and mediate tumor destruction J Immunother 32 7 677 688 10.1097/CJI.0b013e3181ab1824 19561540 10.1097/CJI.0b013e3181ab1824
    • (2009) J Immunother , vol.32 , Issue.7 , pp. 677-688
    • Brandmaier, A.G.1    Leitner, W.W.2    Ha, S.P.3    Sidney, J.4    Restifo, N.P.5    Touloukian, C.E.6
  • 37
    • 77954721060 scopus 로고    scopus 로고
    • Regulatory T cells in tumor immunity
    • 20518016 1:CAS:528:DC%2BC3cXnvFKru7k%3D
    • H Nishikawa S Sakaguchi 2010 Regulatory T cells in tumor immunity Int J Cancer 127 4 759 767 20518016 1:CAS:528:DC%2BC3cXnvFKru7k%3D
    • (2010) Int J Cancer , vol.127 , Issue.4 , pp. 759-767
    • Nishikawa, H.1    Sakaguchi, S.2
  • 38
    • 78649722883 scopus 로고    scopus 로고
    • How specificity for self-peptides shapes the development and function of regulatory T cells
    • 20495071 10.1189/jlb.0310183 1:CAS:528:DC%2BC3cXhsFGgtLzK
    • DM Simons CC Picca S Oh OA Perng M Aitken J Erikson AJ Caton 2010 How specificity for self-peptides shapes the development and function of regulatory T cells J Leukoc Biol 88 6 1099 1107 20495071 10.1189/jlb.0310183 1:CAS:528:DC%2BC3cXhsFGgtLzK
    • (2010) J Leukoc Biol , vol.88 , Issue.6 , pp. 1099-1107
    • Simons, D.M.1    Picca, C.C.2    Oh, S.3    Perng, O.A.4    Aitken, M.5    Erikson, J.6    Caton, A.J.7
  • 40
    • 45549099784 scopus 로고    scopus 로고
    • Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
    • 10.1056/NEJMoa0800251 18565862 10.1056/NEJMoa0800251 1:CAS:528: DC%2BD1cXns1ajtrw%3D
    • NN Hunder H Wallen J Cao DW Hendricks JZ Reilly R Rodmyre A Jungbluth S Gnjatic JA Thompson C Yee 2008 Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1 N Engl J Med 358 25 2698 2703 10.1056/ NEJMoa0800251 18565862 10.1056/NEJMoa0800251 1:CAS:528:DC%2BD1cXns1ajtrw%3D
    • (2008) N Engl J Med , vol.358 , Issue.25 , pp. 2698-2703
    • Hunder, N.N.1    Wallen, H.2    Cao, J.3    Hendricks, D.W.4    Reilly, J.Z.5    Rodmyre, R.6    Jungbluth, A.7    Gnjatic, S.8    Thompson, J.A.9    Yee, C.10
  • 41
    • 41149130863 scopus 로고    scopus 로고
    • Multiple roles for CD4+ T cells in anti-tumor immune responses
    • 10.1111/j.1600-065X.2008.00616.x 18363998 10.1111/j.1600-065X.2008.00616. x 1:CAS:528:DC%2BD1cXlsFejtrk%3D
    • R Kennedy E Celis 2008 Multiple roles for CD4+ T cells in anti-tumor immune responses Immunol Rev 222 129 144 10.1111/j.1600-065X.2008.00616.x 18363998 10.1111/j.1600-065X.2008.00616.x 1:CAS:528:DC%2BD1cXlsFejtrk%3D
    • (2008) Immunol Rev , vol.222 , pp. 129-144
    • Kennedy, R.1    Celis, E.2
  • 43
    • 54249148553 scopus 로고    scopus 로고
    • Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen
    • 18922918 10.1158/0008-5472.CAN-08-1864 1:CAS:528:DC%2BD1cXht1CmsbrI
    • R Bos S van Duikeren H Morreau K Franken TN Schumacher JB Haanen SH van der Burg CJ Melief R Offringa 2008 Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen Cancer Res 68 20 8446 8455 18922918 10.1158/0008-5472.CAN-08-1864 1:CAS:528:DC%2BD1cXht1CmsbrI
    • (2008) Cancer Res , vol.68 , Issue.20 , pp. 8446-8455
    • Bos, R.1    Van Duikeren, S.2    Morreau, H.3    Franken, K.4    Schumacher, T.N.5    Haanen, J.B.6    Van Der Burg, S.H.7    Melief, C.J.8    Offringa, R.9
  • 44
    • 78650124721 scopus 로고    scopus 로고
    • Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice
    • 21145762 10.1016/j.immuni.2010.11.022 1:CAS:528:DC%2BC3cXhsFyisLvM
    • MD Sharma DY Hou B Baban PA Koni Y He PR Chandler BR Blazar AL Mellor DH Munn 2010 Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice Immunity 33 6 942 954 21145762 10.1016/j.immuni.2010.11.022 1:CAS:528:DC%2BC3cXhsFyisLvM
    • (2010) Immunity , vol.33 , Issue.6 , pp. 942-954
    • Sharma, M.D.1    Hou, D.Y.2    Baban, B.3    Koni, P.A.4    He, Y.5    Chandler, P.R.6    Blazar, B.R.7    Mellor, A.L.8    Munn, D.H.9
  • 45
    • 77749245797 scopus 로고    scopus 로고
    • DNA vaccination with T-cell epitopes encoded within Ab molecules induces high-avidity anti-tumor CD8+ T cells
    • 10.1002/eji.200939857 20039301 10.1002/eji.200939857 1:CAS:528: DC%2BC3cXjtVWku70%3D
    • VA Pudney RL Metheringham B Gunn I Spendlove JM Ramage LG Durrant 2010 DNA vaccination with T-cell epitopes encoded within Ab molecules induces high-avidity anti-tumor CD8+ T cells Eur J Immunol 40 3 899 910 10.1002/eji.200939857 20039301 10.1002/eji.200939857 1:CAS:528: DC%2BC3cXjtVWku70%3D
    • (2010) Eur J Immunol , vol.40 , Issue.3 , pp. 899-910
    • Pudney, V.A.1    Metheringham, R.L.2    Gunn, B.3    Spendlove, I.4    Ramage, J.M.5    Durrant, L.G.6
  • 46
    • 77952788825 scopus 로고    scopus 로고
    • Adoptive transfer of tumor-specific Tc17 effector T cells controls the growth of B16 melanoma in mice
    • 10.4049/jimmunol.0902995 20237297 10.4049/jimmunol.0902995
    • L Garcia-Hernandez Mde H Hamada JB Reome SK Misra MP Tighe RW Dutton 2010 Adoptive transfer of tumor-specific Tc17 effector T cells controls the growth of B16 melanoma in mice J Immunol 184 8 4215 4227 10.4049/jimmunol.0902995 20237297 10.4049/jimmunol.0902995
    • (2010) J Immunol , vol.184 , Issue.8 , pp. 4215-4227
    • Garcia-Hernandez Mde, L.1    Hamada, H.2    Reome, J.B.3    Misra, S.K.4    Tighe, M.P.5    Dutton, R.W.6
  • 47
    • 61449184521 scopus 로고    scopus 로고
    • Cutting edge: Phenotypic characterization and differentiation of human CD8+ T cells producing IL-17
    • 10.4049/jimmunol.0801347 19201830 10.4049/jimmunol.0801347 1:CAS:528:DC%2BD1MXhsFKktL4%3D
    • T Kondo H Takata F Matsuki M Takiguchi 2009 Cutting edge: phenotypic characterization and differentiation of human CD8+ T cells producing IL-17 J Immunol 182 4 1794 1798 10.4049/jimmunol.0801347 19201830 10.4049/jimmunol. 0801347 1:CAS:528:DC%2BD1MXhsFKktL4%3D
    • (2009) J Immunol , vol.182 , Issue.4 , pp. 1794-1798
    • Kondo, T.1    Takata, H.2    Matsuki, F.3    Takiguchi, M.4
  • 49
    • 77956397098 scopus 로고    scopus 로고
    • Tumor-activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients
    • 10.4049/jimmunol.0904094 20581151 10.4049/jimmunol.0904094 1:CAS:528:DC%2BC3cXptV2jsb8%3D
    • DM Kuang C Peng Q Zhao Y Wu LY Zhu J Wang XY Yin L Li L Zheng 2010 Tumor-activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients J Immunol 185 3 1544 1549 10.4049/jimmunol. 0904094 20581151 10.4049/jimmunol.0904094 1:CAS:528:DC%2BC3cXptV2jsb8%3D
    • (2010) J Immunol , vol.185 , Issue.3 , pp. 1544-1549
    • Kuang, D.M.1    Peng, C.2    Zhao, Q.3    Wu, Y.4    Zhu, L.Y.5    Wang, J.6    Yin, X.Y.7    Li, L.8    Zheng, L.9
  • 50
    • 48849103649 scopus 로고    scopus 로고
    • Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing
    • 10.1158/1078-0432.CCR-07-5164 18519750 10.1158/1078-0432.CCR-07-5164 1:CAS:528:DC%2BD1cXmslygs70%3D
    • KS Sfanos TC Bruno CH Maris L Xu CJ Thoburn AM DeMarzo AK Meeker WB Isaacs CG Drake 2008 Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing Clin Cancer Res 14 11 3254 3261 10.1158/1078-0432.CCR-07-5164 18519750 10.1158/1078-0432.CCR-07-5164 1:CAS:528:DC%2BD1cXmslygs70%3D
    • (2008) Clin Cancer Res , vol.14 , Issue.11 , pp. 3254-3261
    • Sfanos, K.S.1    Bruno, T.C.2    Maris, C.H.3    Xu, L.4    Thoburn, C.J.5    Demarzo, A.M.6    Meeker, A.K.7    Isaacs, W.B.8    Drake, C.G.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.