Leptin administration alleviates ischemic brain injury in mice by reducing oxidative stress and subsequent neuronal apoptosis

Journal of Trauma and Acute Care Surgery

Volumn 72, Issue 4, 2012, Pages 982-991

  Zhang, Jin Ying ^a   Si, Yi Ling ^a   Liao, Jie ^a   Yan, Guang Tao ^a   Deng, Zi Hui ^a   Xue, Hui ^a   Wang, Lu Huan ^a   Zhang, Kai ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Brain; Leptin; Neuronal apoptosis; Oxidative stress; Reperfusion injury

Indexed keywords

CASPASE 3; IODINE 125; LEPTIN; MALONALDEHYDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TRIPHENYLTETRAZOLIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; BRAIN REGION; BRAIN TISSUE; CONTROLLED STUDY; DOWN REGULATION; HISTOPATHOLOGY; LASER DOPPLER FLOWMETRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; UPREGULATION; ANIMAL; APOPTOSIS; BRAIN CIRCULATION; BRAIN INFARCTION; BRAIN LEVEL; DISEASE MODEL; DRUG EFFECT; METABOLISM;

ANIMALS; APOPTOSIS; BRAIN CHEMISTRY; BRAIN ISCHEMIA; CEREBRAL INFARCTION; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; LEPTIN; MALE; MALONDIALDEHYDE; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

EID: 84862752155     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e3182405459     Document Type: Article

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