메뉴 건너뛰기




Volumn 7, Issue 6, 2012, Pages

Effects of Activin and TGFβ on p21 in Colon cancer

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; ACTIVIN RECEPTOR 2; MESSENGER RNA; PROTEIN P21; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

EID: 84862742711     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039381     Document Type: Article
Times cited : (50)

References (36)
  • 1
    • 0036486076 scopus 로고    scopus 로고
    • Regulation of cell proliferation, apoptosis, and carcinogenesis by activin
    • Chen YG, Lui HM, Lin SL, Lee JM, Ying SY, (2002) Regulation of cell proliferation, apoptosis, and carcinogenesis by activin. Exp Biol Med (Maywood) 227: 75-87.
    • (2002) Exp Biol Med (Maywood) , vol.227 , pp. 75-87
    • Chen, Y.G.1    Lui, H.M.2    Lin, S.L.3    Lee, J.M.4    Ying, S.Y.5
  • 2
    • 33750594064 scopus 로고    scopus 로고
    • Generation of activin receptor type IIB isoform-specific hypomorphic alleles
    • Lee YJ, Hong KH, Yun J, Oh SP, (2006) Generation of activin receptor type IIB isoform-specific hypomorphic alleles. Genesis 44: 487-494.
    • (2006) Genesis , vol.44 , pp. 487-494
    • Lee, Y.J.1    Hong, K.H.2    Yun, J.3    Oh, S.P.4
  • 3
    • 0035881961 scopus 로고    scopus 로고
    • Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability
    • Mori Y, Yin J, Rashid A, Leggett BA, Young J, et al. (2001) Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability. Cancer Res 61: 6046-6049.
    • (2001) Cancer Res , vol.61 , pp. 6046-6049
    • Mori, Y.1    Yin, J.2    Rashid, A.3    Leggett, B.A.4    Young, J.5
  • 4
    • 0037374547 scopus 로고    scopus 로고
    • Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers
    • Hempen PM, Zhang L, Bansal RK, Iacobuzio-Donahue CA, Murphy KM, et al. (2003) Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res 63: 994-999.
    • (2003) Cancer Res , vol.63 , pp. 994-999
    • Hempen, P.M.1    Zhang, L.2    Bansal, R.K.3    Iacobuzio-Donahue, C.A.4    Murphy, K.M.5
  • 5
    • 7444232278 scopus 로고    scopus 로고
    • Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes
    • Deacu E, Mori Y, Sato F, Yin J, Olaru A, et al. (2004) Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes. Cancer Res 64: 7690-7696.
    • (2004) Cancer Res , vol.64 , pp. 7690-7696
    • Deacu, E.1    Mori, Y.2    Sato, F.3    Yin, J.4    Olaru, A.5
  • 6
    • 1542377485 scopus 로고    scopus 로고
    • Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers
    • Jung B, Doctolero RT, Tajima A, Nguyen AK, Keku T, et al. (2004) Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers. Gastroenterology 126: 654-659.
    • (2004) Gastroenterology , vol.126 , pp. 654-659
    • Jung, B.1    Doctolero, R.T.2    Tajima, A.3    Nguyen, A.K.4    Keku, T.5
  • 7
    • 33646391241 scopus 로고    scopus 로고
    • Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers
    • Jung B, Smith EJ, Doctolero RT, Gervaz P, Alonso JC, et al. (2006) Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers. Int J Cancer 118: 2509-2513.
    • (2006) Int J Cancer , vol.118 , pp. 2509-2513
    • Jung, B.1    Smith, E.J.2    Doctolero, R.T.3    Gervaz, P.4    Alonso, J.C.5
  • 8
    • 53049087109 scopus 로고    scopus 로고
    • Genomic instability and molecular pathogenesis of colorectal cancer
    • Grady WM, Carethers JM, (2008) Genomic instability and molecular pathogenesis of colorectal cancer. Gastroenterology 4: 1079-1099.
    • (2008) Gastroenterology , vol.4 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 9
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • Watanabe T, Wu TT, Catalano PJ, Ueki T, Satriano R, et al. (2001) Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 344: 1196-1206.
    • (2001) N Engl J Med , vol.344 , pp. 1196-1206
    • Watanabe, T.1    Wu, T.T.2    Catalano, P.J.3    Ueki, T.4    Satriano, R.5
  • 10
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: intricate networks and multiple activities
    • Abbas T, Dutta A, (2009) p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 9: 400-414.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 11
    • 0038407335 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells
    • Gong J, Ammanamanchi S, Ko TC, Brattain MG, (2003) Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells. Cancer Res 63: 3340-3346.
    • (2003) Cancer Res , vol.63 , pp. 3340-3346
    • Gong, J.1    Ammanamanchi, S.2    Ko, T.C.3    Brattain, M.G.4
  • 12
    • 0030996527 scopus 로고    scopus 로고
    • Activin A induction of cell-cycle arrest involves modulation of cyclin D2 and p21CIP1/WAF1 in plasmacytic cells
    • Yamato K, Koseki T, Ohguchi M, Kizaki M, Ikeda Y, et al. (1997) Activin A induction of cell-cycle arrest involves modulation of cyclin D2 and p21CIP1/WAF1 in plasmacytic cells. Mol Endocrinol 11: 1044-1052.
    • (1997) Mol Endocrinol , vol.11 , pp. 1044-1052
    • Yamato, K.1    Koseki, T.2    Ohguchi, M.3    Kizaki, M.4    Ikeda, Y.5
  • 13
    • 24744446473 scopus 로고    scopus 로고
    • Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells
    • Burdette JE, Jeruss JS, Kurley SJ, Lee EJ, Woodruff TK, (2005) Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells. Cancer Res 65: 7968-7975.
    • (2005) Cancer Res , vol.65 , pp. 7968-7975
    • Burdette, J.E.1    Jeruss, J.S.2    Kurley, S.J.3    Lee, E.J.4    Woodruff, T.K.5
  • 15
    • 0042527227 scopus 로고    scopus 로고
    • Associations of micronutrients with Colon Cancer risk in African Americans and whites: results from the North Carolina Colon Cancer Study
    • Satia-Abouta J, Galanko JA, Martin CF, Potter JD, Ammerman A, et al. (2003) Associations of micronutrients with Colon Cancer risk in African Americans and whites: results from the North Carolina Colon Cancer Study. Cancer Epidemiol Biomarkers Prev 12: 747-754.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 747-754
    • Satia-Abouta, J.1    Galanko, J.A.2    Martin, C.F.3    Potter, J.D.4    Ammerman, A.5
  • 16
    • 0023818612 scopus 로고
    • Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines
    • Boyd D, Florent G, Kim P, Brattain M, (1988) Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines. Cancer research 48: 3112-3116.
    • (1988) Cancer Research , vol.48 , pp. 3112-3116
    • Boyd, D.1    Florent, G.2    Kim, P.3    Brattain, M.4
  • 17
    • 6344252864 scopus 로고    scopus 로고
    • RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta
    • Piek E, Van Dinther M, Parks WT, Sallee JM, Bottinger EP, et al. (2004) RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta. Biochem J 383: 187-199.
    • (2004) Biochem J , vol.383 , pp. 187-199
    • Piek, E.1    van Dinther, M.2    Parks, W.T.3    Sallee, J.M.4    Bottinger, E.P.5
  • 18
    • 0029806078 scopus 로고    scopus 로고
    • Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins
    • Chen Y, Lebrun JJ, Vale W, (1996) Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins. Proc Natl Acad Sci U S A 93: 12992-12997.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12992-12997
    • Chen, Y.1    Lebrun, J.J.2    Vale, W.3
  • 19
    • 54349117710 scopus 로고    scopus 로고
    • TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells
    • Chow JY, Cabral JA, Chang J, Carethers JM, (2008) TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells. Cancer Biol Ther 7: 1694-1699.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1694-1699
    • Chow, J.Y.1    Cabral, J.A.2    Chang, J.3    Carethers, J.M.4
  • 20
    • 33847015309 scopus 로고    scopus 로고
    • Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin
    • Jung BH, Beck SE, Cabral J, Chau E, Cabrera BL, et al. (2007) Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin. Gastroenterology 132: 633-644.
    • (2007) Gastroenterology , vol.132 , pp. 633-644
    • Jung, B.H.1    Beck, S.E.2    Cabral, J.3    Chau, E.4    Cabrera, B.L.5
  • 21
    • 34249340845 scopus 로고    scopus 로고
    • BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK
    • Beck SE, Jung BH, Del Rosario E, Gomez J, Carethers JM, (2007) BMP-induced growth suppression in colon cancer cells is mediated by p21WAF1 stabilization and modulated by RAS/ERK. Cell Signal 19: 1465-1472.
    • (2007) Cell Signal , vol.19 , pp. 1465-1472
    • Beck, S.E.1    Jung, B.H.2    Del Rosario, E.3    Gomez, J.4    Carethers, J.M.5
  • 23
    • 33645101402 scopus 로고    scopus 로고
    • Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells
    • Grau AM, Datta PK, Zi J, Halder SK, Beauchamp RD, (2006) Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells. Cell Signal 18: 1041-1050.
    • (2006) Cell Signal , vol.18 , pp. 1041-1050
    • Grau, A.M.1    Datta, P.K.2    Zi, J.3    Halder, S.K.4    Beauchamp, R.D.5
  • 24
    • 0141429168 scopus 로고    scopus 로고
    • UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair
    • Bendjennat M, Boulaire J, Jascur T, Brickner H, Barbier V, et al. (2003) UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair. Cell 114: 599-610.
    • (2003) Cell , vol.114 , pp. 599-610
    • Bendjennat, M.1    Boulaire, J.2    Jascur, T.3    Brickner, H.4    Barbier, V.5
  • 25
    • 0033623850 scopus 로고    scopus 로고
    • Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination
    • Sheaff RJ, Singer JD, Swanger J, Smitherman M, Roberts JM, et al. (2000) Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination. Mol Cell 5: 403-410.
    • (2000) Mol Cell , vol.5 , pp. 403-410
    • Sheaff, R.J.1    Singer, J.D.2    Swanger, J.3    Smitherman, M.4    Roberts, J.M.5
  • 26
    • 0032527902 scopus 로고    scopus 로고
    • Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas
    • Grady WM, Rajput A, Myeroff L, Liu DF, Kwon K, et al. (1998) Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas. Cancer Res 58: 3101-3104.
    • (1998) Cancer Res , vol.58 , pp. 3101-3104
    • Grady, W.M.1    Rajput, A.2    Myeroff, L.3    Liu, D.F.4    Kwon, K.5
  • 27
    • 33750565444 scopus 로고    scopus 로고
    • Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation
    • Munoz NM, Upton M, Rojas A, Washington MK, Lin L, et al. (2006) Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Res 66: 9837-9844.
    • (2006) Cancer Res , vol.66 , pp. 9837-9844
    • Munoz, N.M.1    Upton, M.2    Rojas, A.3    Washington, M.K.4    Lin, L.5
  • 28
    • 67649205804 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21Cip1
    • Hwang CY, Lee C, Kwon KS, (2009) Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21Cip1. Mol Cell Biol 29: 3379-3389.
    • (2009) Mol Cell Biol , vol.29 , pp. 3379-3389
    • Hwang, C.Y.1    Lee, C.2    Kwon, K.S.3
  • 29
    • 17044378584 scopus 로고    scopus 로고
    • Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling
    • Datto M, Wang XF, (2005) Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling. Cell 121: 2-4.
    • (2005) Cell , vol.121 , pp. 2-4
    • Datto, M.1    Wang, X.F.2
  • 30
    • 0034025130 scopus 로고    scopus 로고
    • Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas
    • Bukholm IK, Nesland JM, (2000) Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas. Virchows Arch 436: 224-228.
    • (2000) Virchows Arch , vol.436 , pp. 224-228
    • Bukholm, I.K.1    Nesland, J.M.2
  • 31
    • 0030057835 scopus 로고    scopus 로고
    • Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia
    • Polyak K, Hamilton SR, Vogelstein B, Kinzler KW, (1996) Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia. Am J Pathol 149: 381-387.
    • (1996) Am J Pathol , vol.149 , pp. 381-387
    • Polyak, K.1    Hamilton, S.R.2    Vogelstein, B.3    Kinzler, K.W.4
  • 33
    • 25844457395 scopus 로고    scopus 로고
    • Venous invasion and down-regulation of p21(WAF1/CIP1) are associated with metastasis in colorectal carcinomas
    • Mitomi H, Mori A, Kanazawa H, Nishiyama Y, Ihara A, et al. (2005) Venous invasion and down-regulation of p21(WAF1/CIP1) are associated with metastasis in colorectal carcinomas. Hepatogastroenterology 52: 1421-1426.
    • (2005) Hepatogastroenterology , vol.52 , pp. 1421-1426
    • Mitomi, H.1    Mori, A.2    Kanazawa, H.3    Nishiyama, Y.4    Ihara, A.5
  • 34
    • 21044432331 scopus 로고    scopus 로고
    • A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol
    • Shah MA, Kortmansky J, Motwani M, Drobnjak M, Gonen M, et al. (2005) A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol. Clin Cancer Res 11: 3836-3845.
    • (2005) Clin Cancer Res , vol.11 , pp. 3836-3845
    • Shah, M.A.1    Kortmansky, J.2    Motwani, M.3    Drobnjak, M.4    Gonen, M.5
  • 35
    • 0142058036 scopus 로고    scopus 로고
    • Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy
    • Rau B, Sturm I, Lage H, Berger S, Schneider U, et al. (2003) Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy. J Clin Oncol 21: 3391-3401.
    • (2003) J Clin Oncol , vol.21 , pp. 3391-3401
    • Rau, B.1    Sturm, I.2    Lage, H.3    Berger, S.4    Schneider, U.5
  • 36
    • 0032527902 scopus 로고    scopus 로고
    • Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas
    • Grady WM, Rajput A, Myeroff L, Liu DF, Kwon K, et al. (1998) Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas. Cancer research 58: 3101-3104.
    • (1998) Cancer Research , vol.58 , pp. 3101-3104
    • Grady, W.M.1    Rajput, A.2    Myeroff, L.3    Liu, D.F.4    Kwon, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.