Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival

British Journal of Pharmacology

Volumn 166, Issue 5, 2012, Pages 1605-1616

  Lim, Keng Gat ^a   Gray, Alexander I ^a   Pyne, Susan ^a   Pyne, Nigel J ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

ampelopsin A; apoptosis; balanocarpol; cancer; extracellular signal regulated kinase; inhibitor kinetics; polyADP ribose polymerase; proliferation; resveratrol; sphingosine 1 phosphate; sphingosine kinase 1

Indexed keywords

AMPELOPSIN A; BALANOCARPOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHENOL DERIVATIVE; RESVERATROL; SPHINGOSINE KINASE 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL GROWTH; CELL STRAIN MCF 7; CELL SURVIVAL; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; ENZYME INHIBITORS; HUMANS; NEOPLASMS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); STILBENES;

EID: 84862739877     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01862.x     Document Type: Article

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