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Volumn 12, Issue 2, 2012, Pages 84-94

Serum leptin levels negatively correlate with trabecular bone mineral density in high-fat diet-induced obesity mice

Author keywords

Bone quality; Leptin; Obesity; Osteoporosis; pQCT

Indexed keywords

ADIPONECTIN; CHOLESTEROL; INSULIN; LEPTIN; TRIACYLGLYCEROL;

EID: 84862732706     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (59)

References (57)
  • 2
    • 0004318660 scopus 로고    scopus 로고
    • World Health Organization, Report of a WHO consultation. World Health Organization technical report series 894. Geneva: WHO
    • World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organization technical report series 894. Geneva: WHO; 2000.
    • (2000) Obesity: Preventing and Managing the Global Epidemic
  • 3
    • 3242765196 scopus 로고    scopus 로고
    • Obesity in children and young people: A crisis in public health
    • IASO International Obesity TaskForce
    • Lobstein T, Baur L, Uauy R; IASO International Obesity TaskForce. Obesity in children and young people: a crisis in public health. Obes Rev 2004;5(Suppl. 1):4-104.
    • (2004) Obes Rev , vol.5 , Issue.SUPPL. 1 , pp. 4-104
    • Lobstein, T.1    Baur, L.2    Uauy, R.3
  • 4
    • 33748071110 scopus 로고    scopus 로고
    • Association between bone mass and fractures in children: A prospective cohort study
    • Clark EM, Ness AR, Bishop NJ, Tobias JH. Association between bone mass and fractures in children: a prospective cohort study. J Bone Miner Res 2006;21:1489-1495.
    • (2006) J Bone Miner Res , vol.21 , pp. 1489-1495
    • Clark, E.M.1    Ness, A.R.2    Bishop, N.J.3    Tobias, J.H.4
  • 5
    • 28144448365 scopus 로고    scopus 로고
    • Bone and body composition of children and adolescents with repeated forearm fractures
    • Goulding A, Grant AM, Williams SM. Bone and body composition of children and adolescents with repeated forearm fractures. J Bone Miner Res 2005;20:2090-2096.
    • (2005) J Bone Miner Res , vol.20 , pp. 2090-2096
    • Goulding, A.1    Grant, A.M.2    Williams, S.M.3
  • 6
    • 0028566222 scopus 로고
    • Volumetric bone density of the lumbar spine is related to fat mass but not lean mass in normal postmenopausal women
    • Reid IR, Evans MC, Ames RW. Volumetric bone density of the lumbar spine is related to fat mass but not lean mass in normal postmenopausal women. Osteoporos Int 1994; 4:362-367.
    • (1994) Osteoporos Int , vol.4 , pp. 362-367
    • Reid, I.R.1    Evans, M.C.2    Ames, R.W.3
  • 8
    • 84874772179 scopus 로고    scopus 로고
    • The Ministry of Health Labour and Welfare. Assessed at, 17 December, (in Japanease)
    • The Ministry of Health Labour and Welfare. Assessed at http://www.mhlw.go.jp/stf/houdou/2r9852000000xtwq.html on 17 December 2010 (in Japanease).
    • (2010)
  • 11
    • 78249259079 scopus 로고    scopus 로고
    • High fat diet-induced animal model of age-associated obesity and osteoporosis
    • Halade GV, Rahman MM, Williams PJ, Fernandes G. High fat diet-induced animal model of age-associated obesity and osteoporosis. J Nutr Biochem 2010;21:1162-1169.
    • (2010) J Nutr Biochem , vol.21 , pp. 1162-1169
    • Halade, G.V.1    Rahman, M.M.2    Williams, P.J.3    Fernandes, G.4
  • 12
    • 77956408745 scopus 로고    scopus 로고
    • Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: Modulation by diet-induced obesity
    • Bartelt A, Beil FT, Schinke T, Roeser K, Ruether W, Heeren J, Niemeier A. Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity. Bone 2010;47:736-745.
    • (2010) Bone , vol.47 , pp. 736-745
    • Bartelt, A.1    Beil, F.T.2    Schinke, T.3    Roeser, K.4    Ruether, W.5    Heeren, J.6    Niemeier, A.7
  • 13
    • 0036090574 scopus 로고    scopus 로고
    • Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta
    • Okazaki R, Inoue D, Shibata M, Saika M, Kido S, Ooka H, Tomiyama H, Sakamoto Y, Matsumoto T. Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta. Endocrinology 2002;143:2349-2356.
    • (2002) Endocrinology , vol.143 , pp. 2349-2356
    • Okazaki, R.1    Inoue, D.2    Shibata, M.3    Saika, M.4    Kido, S.5    Ooka, H.6    Tomiyama, H.7    Sakamoto, Y.8    Matsumoto, T.9
  • 14
    • 0036861322 scopus 로고    scopus 로고
    • Relationships among body mass, its components, and bone
    • Reid IR. Relationships among body mass, its components, and bone. Bone 2002 31:547-555.
    • (2002) Bone , vol.31 , pp. 547-555
    • Reid, I.R.1
  • 15
    • 0034575063 scopus 로고    scopus 로고
    • Increased bone mineral density and serum leptin in non-obese girls with precocious pubarche: Relation to low birthweight and hyperinsulinism
    • Ibáñez L, Potau N, Ong K, Dunger DB, De Zegher F. Increased bone mineral density and serum leptin in non-obese girls with precocious pubarche: relation to low birthweight and hyperinsulinism. Horm Res 2000;54:192-197.
    • (2000) Horm Res , vol.54 , pp. 192-197
    • Ibáñez, L.1    Potau, N.2    Ong, K.3    Dunger, D.B.4    de Zegher, F.5
  • 21
    • 34147184714 scopus 로고    scopus 로고
    • Serum leptin and adiponectin are positively associated with bone mineral density at the distal radius in patients with type 2 diabetes mellitus
    • Tamura T, Yoneda M, Yamane K, Nakanishi S, Nakashima R, Okubo M, Kohno N. Serum leptin and adiponectin are positively associated with bone mineral density at the distal radius in patients with type 2 diabetes mellitus. Metabolism 2007;56:623-628.
    • (2007) Metabolism , vol.56 , pp. 623-628
    • Tamura, T.1    Yoneda, M.2    Yamane, K.3    Nakanishi, S.4    Nakashima, R.5    Okubo, M.6    Kohno, N.7
  • 22
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the re-formulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the re-formulation of the AIN-76A rodent diet. J Nutr 1993; 123:1939-1951.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey Jr., G.C.3
  • 24
    • 0032145985 scopus 로고    scopus 로고
    • Comparison of three-point bending test and peripheral quantitative computed tomography analysis in the evaluation of the strength of mouse femur and tibia
    • Jämsä T, Jalovaara P, Peng Z, Väänänen HK, Tuukkanen J. Comparison of three-point bending test and peripheral quantitative computed tomography analysis in the evaluation of the strength of mouse femur and tibia. Bone 1998;23:155-161.
    • (1998) Bone , vol.23 , pp. 155-161
    • Jämsä, T.1    Jalovaara, P.2    Peng, Z.3    Väänänen, H.K.4    Tuukkanen, J.5
  • 25
    • 72049127578 scopus 로고    scopus 로고
    • Elcatonin injections suppress systemic bone resorption without affecting cortical bone regeneration after drill-hole injuries in mice
    • Katae Y, Tanaka S, Sakai A, Nagashima M, Hirasawa H, Nakamura T. Elcatonin injections suppress systemic bone resorption without affecting cortical bone regeneration after drill-hole injuries in mice. J Orthop Res 2009; 27:1652-1658.
    • (2009) J Orthop Res , vol.27 , pp. 1652-1658
    • Katae, Y.1    Tanaka, S.2    Sakai, A.3    Nagashima, M.4    Hirasawa, H.5    Nakamura, T.6
  • 26
    • 33845883071 scopus 로고    scopus 로고
    • Bone loss and increased bone adiposity in spontaneous and pharmacologically induced diabetic mice
    • Botolin S, McCabe LR. Bone loss and increased bone adiposity in spontaneous and pharmacologically induced diabetic mice. Endocrinology 2007;148:198-205.
    • (2007) Endocrinology , vol.148 , pp. 198-205
    • Botolin, S.1    McCabe, L.R.2
  • 28
    • 67349252445 scopus 로고    scopus 로고
    • High-fat diet decreases can-cellous bone mass but has no effect on cortical bone mass in the tibia in mice
    • Cao JJ, Gregoire BR, Gao H. High-fat diet decreases can-cellous bone mass but has no effect on cortical bone mass in the tibia in mice. Bone 2009;44:1097-1104.
    • (2009) Bone , vol.44 , pp. 1097-1104
    • Cao, J.J.1    Gregoire, B.R.2    Gao, H.3
  • 29
    • 17844365292 scopus 로고    scopus 로고
    • Ratio of n-6 to n-3 fatty acids and bone mineral density in older adults: The Rancho Bernardo Study
    • Weiss LA, Barrett-Connor E, von Mühlen D. Ratio of n-6 to n-3 fatty acids and bone mineral density in older adults: the Rancho Bernardo Study. Am J Clin Nutr 2005; 81:934-938.
    • (2005) Am J Clin Nutr , vol.81 , pp. 934-938
    • Weiss, L.A.1    Barrett-Connor, E.2    von Mühlen, D.3
  • 30
    • 0033858989 scopus 로고    scopus 로고
    • Dietary ratio of (n-6)/(n-3) polyunsaturated fatty acids alters the fatty acid composition of bone compartments and biomarkers of bone formation in rats
    • Watkins BA, Li Y, Allen KG, Hoffmann WE, Seifert MF. Dietary ratio of (n-6)/(n-3) polyunsaturated fatty acids alters the fatty acid composition of bone compartments and biomarkers of bone formation in rats. J Nutr 2000; 130:2274-2284.
    • (2000) J Nutr , vol.130 , pp. 2274-2284
    • Watkins, B.A.1    Li, Y.2    Allen, K.G.3    Hoffmann, W.E.4    Seifert, M.F.5
  • 31
    • 34548080918 scopus 로고    scopus 로고
    • Age-related changes in trabecular architecture differ in female and male C57BL/6J mice
    • Glatt V, Canalis E, Stadmeyer L, Bouxsein ML. Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res 2007; 22:1197-1207.
    • (2007) J Bone Miner Res , vol.22 , pp. 1197-1207
    • Glatt, V.1    Canalis, E.2    Stadmeyer, L.3    Bouxsein, M.L.4
  • 34
    • 34247857663 scopus 로고    scopus 로고
    • Obesity, inflammation, and insulin resistance
    • Shoelson SE, Herrero L, Naaz A. Obesity, inflammation, and insulin resistance. Gastroenterology 2007;132:2169-2180.
    • (2007) Gastroenterology , vol.132 , pp. 2169-2180
    • Shoelson, S.E.1    Herrero, L.2    Naaz, A.3
  • 35
    • 55849114349 scopus 로고    scopus 로고
    • Adipocytokines and the metabolic complications of obesity
    • Rasouli N, Kern PA. Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab 2008; 93:S64-S73.
    • (2008) J Clin Endocrinol Metab , vol.93
    • Rasouli, N.1    Kern, P.A.2
  • 36
    • 0035206443 scopus 로고    scopus 로고
    • Minireview: The OPG/RANKL/RANK system
    • Khosla S. Minireview: the OPG/RANKL/RANK system. Endocrinology 2001;142:5050-5055.
    • (2001) Endocrinology , vol.142 , pp. 5050-5055
    • Khosla, S.1
  • 38
    • 62749120123 scopus 로고    scopus 로고
    • Osteoclas-togenesis by bone marrow-derived macrophages is enhanced in obese mice
    • Kyung TW, Lee JE, Phan TV, Yu R, Choi HS. Osteoclas-togenesis by bone marrow-derived macrophages is enhanced in obese mice. J Nutr 2009;139:502-506.
    • (2009) J Nutr , vol.139 , pp. 502-506
    • Kyung, T.W.1    Lee, J.E.2    Phan, T.V.3    Yu, R.4    Choi, H.S.5
  • 39
    • 34249776946 scopus 로고    scopus 로고
    • Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis
    • David V, Martin A, Lafage-Proust MH, Malaval L, Pey-roche S, Jones DB, Vico L, Guignandon A. Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis. Endocrinology 2007;148:2553-2562.
    • (2007) Endocrinology , vol.148 , pp. 2553-2562
    • David, V.1    Martin, A.2    Lafage-Proust, M.H.3    Malaval, L.4    Pey-Roche, S.5    Jones, D.B.6    Vico, L.7    Guignandon, A.8
  • 40
    • 57349115394 scopus 로고    scopus 로고
    • Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal
    • Sen B, Xie Z, Case N, Ma M, Rubin C, Rubin J. Mechanical strain inhibits adipogenesis in mesenchymal stem cells by stimulating a durable beta-catenin signal. Endocrinology 2008;149:6065-6075.
    • (2008) Endocrinology , vol.149 , pp. 6065-6075
    • Sen, B.1    Xie, Z.2    Case, N.3    Ma, M.4    Rubin, C.5    Rubin, J.6
  • 41
    • 77953391086 scopus 로고    scopus 로고
    • Fat and bone in children: Differential effects of obesity on bone size and mass according to fracture history
    • Dimitri P, Wales JK, Bishop N. Fat and bone in children: differential effects of obesity on bone size and mass according to fracture history. J Bone Miner Res 2010; 25:527-536.
    • (2010) J Bone Miner Res , vol.25 , pp. 527-536
    • Dimitri, P.1    Wales, J.K.2    Bishop, N.3
  • 42
    • 34548596825 scopus 로고    scopus 로고
    • Osteoporosis in children and adolescents
    • Bianchi ML. Osteoporosis in children and adolescents. Bone 2007;41:486-495.
    • (2007) Bone , vol.41 , pp. 486-495
    • Bianchi, M.L.1
  • 43
    • 0036847619 scopus 로고    scopus 로고
    • Leptin regulates bone formation via the sympathetic nervous system
    • Takeda S, Elefteriou F, Levasseur R et al. Leptin regulates bone formation via the sympathetic nervous system. Cell 2002;111:305-317.
    • (2002) Cell , vol.111 , pp. 305-317
    • Takeda, S.1    Elefteriou, F.2    Levasseur, R.3
  • 44
    • 1842632365 scopus 로고    scopus 로고
    • Direct actions of leptin on bone remodeling
    • Reid IR, Comish J. Direct actions of leptin on bone remodeling. Calcif Tissue Int 2004;74:313-316.
    • (2004) Calcif Tissue Int , vol.74 , pp. 313-316
    • Reid, I.R.1    Comish, J.2
  • 45
    • 0242403083 scopus 로고    scopus 로고
    • Leptin: Cutting the fat off the bone
    • Cock TA, Auwerx J. Leptin: cutting the fat off the bone. Lancet 2003;362:1572-1574.
    • (2003) Lancet , vol.362 , pp. 1572-1574
    • Cock, T.A.1    Auwerx, J.2
  • 47
    • 0033303803 scopus 로고    scopus 로고
    • Response of bipotential human marrow stromal cells to insulin-like growthfactors: Effect on binding protein production, proliferation, and commitmentto osteoblasts and adipocytes
    • Thomas T, Gori F, Spelsberg TC, Khosla S, Riggs BL, Conover CA. Response of bipotential human marrow stromal cells to insulin-like growthfactors: effect on binding protein production, proliferation, and commitmentto osteoblasts and adipocytes. Endocrinology 1999;140:5036-5044.
    • (1999) Endocrinology , vol.140 , pp. 5036-5044
    • Thomas, T.1    Gori, F.2    Spelsberg, T.C.3    Khosla, S.4    Riggs, B.L.5    Conover, C.A.6
  • 52
    • 34047197114 scopus 로고    scopus 로고
    • Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice
    • Bullen JW Jr, Bluher S, Kelesidis T, Mantzoros CS. Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. Am J Physiol Endocrinol Metab 2007;292:E1079-E1086.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Bullen Jr., J.W.1    Bluher, S.2    Kelesidis, T.3    Mantzoros, C.S.4
  • 54
    • 49649102639 scopus 로고    scopus 로고
    • High-fat diet-induced changes in body mass and hypothalamic gene expression in wild-type and leptin-deficient mice
    • Townsend KL, Lorenzi MM, Widmaier EP. High-fat diet-induced changes in body mass and hypothalamic gene expression in wild-type and leptin-deficient mice. Endocrine 2008;33:176-188.
    • (2008) Endocrine , vol.33 , pp. 176-188
    • Townsend, K.L.1    Lorenzi, M.M.2    Widmaier, E.P.3
  • 55
    • 79951609432 scopus 로고    scopus 로고
    • Insulin resistance secondary to a high-fat diet stimulates longitudinal bone growth and growth plate chondrogenesis in mice
    • Wu S, Aguilar AL, Ostrow V, De Luca F. Insulin resistance secondary to a high-fat diet stimulates longitudinal bone growth and growth plate chondrogenesis in mice. Endocrinology 2011;152:468-475.
    • (2011) Endocrinology , vol.152 , pp. 468-475
    • Wu, S.1    Aguilar, A.L.2    Ostrow, V.3    de Luca, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.