Maternal exposure to di-(2-ethylhexyl)phthalate alters kidney development through the renin-angiotensin system in offspring

Toxicology Letters

Volumn 212, Issue 2, 2012, Pages 212-221

  Wei, Zhengzheng ^a   Song, Liqiong ^a   Wei, Jie ^a   Chen, Tian ^a   Chen, Jun ^a   Lin, Yi ^a   Xia, Wei ^a   Xu, Bing ^a   Li, Xuguang ^a   Chen, Xi ^a   Li, Yuanyuan ^a   Xu, Shunqing ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Di (2 ethylhexyl)phthalate; Early development; Nephron numbers; RAS; Renal dysfunction

Indexed keywords

ANGIOTENSIN II; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; BONE MORPHOGENETIC PROTEIN 4 GENE; BOWMAN CAPSULE; CADHERIN 11 GENE; CALMODULIN 1 GENE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FIBROSING ALVEOLITIS; FORKHEAD BOX D1 GENE; GENE; GESTATION PERIOD; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR GENE; GLOMERULOSCLEROSIS; HEART RATE; KIDNEY DEVELOPMENT; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY MASS; LITTER SIZE; MALE; NEPHRON; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PAIRED BOX 2 GENE; PERINATAL PERIOD; PODOCYTE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TYROSINE 3 MONOOXYGENASE ACTIVATION PROTEIN GENE; WEANING; WINGLESS TYPE MMTV INTEGRATION SITE 11 GENE;

ANIMALS; BLOOD PRESSURE; CADHERINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HEART RATE; KIDNEY; LITTER SIZE; MALE; PHTHALIC ACIDS; PPAR GAMMA; RATS; RATS, WISTAR; RENIN-ANGIOTENSIN SYSTEM;

RATTUS;

EID: 84862705512     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.05.023     Document Type: Article

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