Targeting of the prostacyclin specific IP1 receptor in lungs with molecular conjugates comprising prostaglandin I2 analogues

Biomaterials

Volumn 31, Issue 10, 2010, Pages 2903-2911

  Geiger, Johannes ^a,b   Aneja, Manish K ^a   Hasenpusch, Günther ^a   Yüksekdag, Gülnihal ^a   Kummerlöwe, Grit ^c   Luy, Burkhard ^c   Romer, Tina ^a   Rothbauer, Ulrich ^a   Rudolph, Carsten ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Aerosol; Gene expression; Gene transfer; Iloprost; Lung; Polyethylenimine

Indexed keywords

AEROSOL DELIVERY; ALVEOLAR EPITHELIAL CELLS; COUPLING DEGREE; DNA BINDING; EPITHELIAL CELLS; GENE DELIVERY; GENE VECTORS; ILOPROST; IN-VITRO; IN-VIVO; LUNG CELLS; OPTIMIZED CONDITIONS; PARTICLE FORMATIONS; POLYETHYLENIMINES; RECEPTOR ANTAGONISTS; RECEPTOR EXPRESSION; SITE-SPECIFIC; TRANSFECTION EFFICIENCY; WESTERN BLOTS;

ATMOSPHERIC AEROSOLS; BIOACTIVITY; BIOLOGICAL ORGANS; BODY FLUIDS; CELL CULTURE; CELLS; CONFOCAL MICROSCOPY; GENE EXPRESSION; NUCLEIC ACIDS;

GENE TRANSFER;

ILOPROST; POLYETHYLENEIMINE; PROSTACYCLIN DERIVATIVE; PROSTACYCLIN RECEPTOR; UNIPROST;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERNALIZATION; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BLOTTING, WESTERN; CATTLE; CELL LINE; EPITHELIAL CELLS; EPOPROSTENOL; FEMALE; FLUORESCEIN; GENETIC VECTORS; HUMANS; ILOPROST; LIGANDS; LUNG; MICE; MICE, INBRED BALB C; ORGAN SPECIFICITY; POLYETHYLENEIMINE; RECEPTORS, EPOPROSTENOL; REPRODUCIBILITY OF RESULTS; SERUM ALBUMIN, BOVINE; TRANSFECTION;

MUS;

EID: 75149141385     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.12.035     Document Type: Article

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