Cross-linked DNA: Site-selective "click" ligation in duplexes with bis-azides and stability changes caused by internal cross-links

Bioconjugate Chemistry

Volumn 23, Issue 6, 2012, Pages 1230-1243

  Xiong, Hai ^a,b   Seela, Frank ^a,b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CROSSLINKING; OLIGONUCLEOTIDES;

5-SUBSTITUTED PYRIMIDINE; CHEMOSELECTIVE; CLICK REACTION; CROSS LINKING; HOMODIMERS; OLIGONUCLEOTIDE DUPLEXES; PRODUCT IDENTIFICATION; PYRIMIDINE NUCLEOSIDES; SITE SELECTIVE; SYNTHESISED;

DNA;

AZIDE; DOUBLE STRANDED DNA; HETERODIMER; HOMODIMER; NUCLEIC ACID BASE; NUCLEOSIDE; OLIGONUCLEOTIDE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ALKYNYLATION; ARTICLE; CLICK CHEMISTRY; CYCLOADDITION; DNA CROSS LINKING; DNA DENATURATION; DNA DETERMINATION; DNA HYBRIDIZATION; DNA MODIFICATION; DNA PURIFICATION; DNA STRUCTURE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR STABILITY; NUCLEIC ACID SYNTHESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS;

AZIDES; BASE SEQUENCE; CLICK CHEMISTRY; CROSS-LINKING REAGENTS; DNA; NUCLEIC ACID DENATURATION; PURINES; PYRIMIDINE NUCLEOSIDES;

EID: 84862696549     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc300074k     Document Type: Article

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