Nucleosides and oligonucleotides with diynyl side chains: Base pairing and functionalization of 2′-deoxyuridine derivatives by the copper(I)-catalyzed alkyne-azide 'click' cycloaddition

Helvetica Chimica Acta

Volumn 90, Issue 3, 2007, Pages 535-552

  Seela, Frank ^a   Sirivolu, Venkata Ramana ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AZIDO COMPOUND; FUNCTIONALIZATION REACTIONS; NUCLEOSIDES;

ADDITION REACTIONS; CATALYST ACTIVITY; CHEMICAL BONDS; DERIVATIVES; MOLECULAR STRUCTURE;

OLIGOMERS;

1 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 5 (OCT 1 YNYL)URACIL; 1 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 5 (OCTA 1,7 DIYNYL)URACIL; 1 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 5 [3 (PROP 2 YNYLOXY)PROP 1 YNYL]URACIL; 1 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 5 (OCT 1,7 DIYNYL)URACIL 3' (2 CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE; 1 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 5 (OCTA 1 DIYNYL)URACIL; 1 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 5 (OCTA 1,7 DIYNYL)URACIL; 1 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 5 (OCTA 1,7 DIYNYL)URACIL 3' (2 CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE; 1 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 5 [3 (PROP 2 YNYLOXY)PROP 1 YNYL)URACIL 3' (2 CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE; 1 [2 DEOXY 5 O (4,4' DIMETHOXYTRITYL) BETA DEXTRO ERYTHRO PENTOFURANOSYL] 5 [3 (PROP 2 YNYLOXY)PROP 1 YNYL]URACIL; ALPHA [5 [1 (ACETYL 5 NITROPHENYL) 1H 1,2,3, TRIAZOL 4 YL]PENTYLIDYNE]THYMIDINE; ALPHA [5 [1[ TETRAHYDRO 2 (HYDROXYMETHYL) 5 (1,2,3,4 TETRAHYDRO 5 METHYL 2,4 DIOXOPYRIMIDIN 1 YL)FURAN 3 YL] 1H 1,2,3 TRIAZOL 4 YL]PENTYLIDYNE]THYMIDINE; NUCLEOSIDE ANALOG; OLIGONUCLEOTIDE; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ARTICLE; BASE PAIRING; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLOADDITION; HYDROLYSIS; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTION; SYNTHESIS;

EID: 34250023096     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200790055     Document Type: Article

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