Structural, energetic, and mechanical perturbations in rhodopsin mutant that causes congenital stationary night blindness

Journal of Biological Chemistry

Volumn 287, Issue 26, 2012, Pages 21826-21835

  Kawamura, Shiho ^a   Colozo, Alejandro T ^b   Ge, Lin ^a   Müller, Daniel J ^a   Park, Paul S H ^b  

^a ETH ZURICH   (Switzerland)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE STATE; AMINO ACID RESIDUES; CONSTITUTIVELY ACTIVES; DARK STATE; ENERGETIC STABILITY; MECHANICAL PERTURBATIONS; MECHANICAL RIGIDITY; MOLECULAR LEVELS; POINT MUTATIONS; RETINAL DISEASE; RETINITIS PIGMENTOSA; ROD PHOTORECEPTORS; SINGLE MOLECULE FORCE SPECTROSCOPY; STRUCTURAL CHANGE; TRANSGENIC MICE; UV-VISIBLE ABSORBANCE SPECTROSCOPY; WILD TYPES;

AMINO ACIDS; CHROMOPHORES; MOLECULES;

EYE PROTECTION;

ASPARTIC ACID; GLYCINE; HYDROXYLAMINE; RHODOPSIN;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BINDING SITE; CHROMATOPHORE; CONGENITAL STATIONARY NIGHT BLINDNESS; CONTROLLED STUDY; DARKNESS; DISEASE MODEL; GENE MUTATION; ILLUMINATION; MOLECULAR MECHANICS; MOUSE; NIGHT BLINDNESS; NONHUMAN; PATHOGENESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RETINA ROD; RETINA ROD OUTER SEGMENT; RHODOPSIN GENE; SINGLE MOLECULE FORCE SPECTROSCOPY; SPECTROSCOPY; TRANSGENIC MOUSE; ULTRAVIOLET SPECTROSCOPY; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; EYE DISEASES, HEREDITARY; GENETIC DISEASES, X-LINKED; MICE; MICE, TRANSGENIC; MICROSCOPY, ATOMIC FORCE; MOLECULAR SEQUENCE DATA; MUTATION; MYOPIA; NIGHT BLINDNESS; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; RHODOPSIN; ROD CELL OUTER SEGMENT; SPECTROPHOTOMETRY; STRESS, MECHANICAL; THERMODYNAMICS; ULTRAVIOLET RAYS;

EID: 84862690475     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.340182     Document Type: Article

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