Functional evaluation of a fluorescent schweinfurthin: Mechanism of cytotoxicity and intracellular quantification

Molecular Pharmacology

Volumn 82, Issue 1, 2012, Pages 9-16

  Kuder, Craig H ^a   Sheehy, Ryan M ^a   Neighbors, Jeffrey D ^b   Wiemer, David F ^a,b   Hohl, Raymond J ^a  

^a UNIVERSITY OF IOWA   (United States)

^b E11 SSH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 DEOXYSCHWEINFURTHIN B; 3 DEOXYSCHWEINFURTHIN B LIKE P NITRO BIS STILBENE; ANTINEOPLASTIC AGENT; CASPASE 9 INHIBITOR; CHAPERONE; GLUCOSE REGULATED PROTEIN 78; LEU GLU(O METHYL) HIS ASP(O METHYL) FLUOROMETHYLKETONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN DISULFIDE ISOMERASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL STRESS; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; FLUORESCENCE; HUMAN; HUMAN CELL; LUNG CARCINOMA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION;

APOPTOSIS; CASPASE 9; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; FLUORESCENT DYES; GLIOBLASTOMA; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MEMBRANE PROTEINS; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN DISULFIDE-ISOMERASES; STILBENES; UP-REGULATION;

EID: 84862570792     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.077107     Document Type: Article

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