Diethylpyrocarbonate labeling for the structural analysis of proteins: Label scrambling in solution and how to avoid it

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 5, 2012, Pages 899-907

  Zhou, Yuping ^a   Vachet, Richard W ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Covalent labeling; MS MS; Protein structure

Indexed keywords

COVALENT LABELING; CYS RESIDUES; DIETHYLPYROCARBONATE; DISULFIDE BONDS; DISULFIDE REDUCTION; LABELING REAGENT; MODIFIED AMINO ACIDS; MS/MS; PROTEIN DIGESTION; PROTEIN STRUCTURES; STRUCTURAL INFORMATION;

AMINO ACIDS; COVALENT BONDS; MASS SPECTROMETRY;

PROTEINS;

CYSTEINE; DIETHYL PYROCARBONATE; DISULFIDE; PEPTIDE DERIVATIVE;

ALKYLATION; AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL LABELING; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; DISULFIDE BOND; ION TRAP MASS SPECTROMETRY; PROTEIN ANALYSIS; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; CYSTEINE; DIETHYL PYROCARBONATE; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; PROTEINS; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84862560973     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-012-0349-3     Document Type: Article

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