Histopathologic evaluation of liver biopsy for cirrhosis

Advances in Anatomic Pathology

Volumn 19, Issue 4, 2012, Pages 220-230

  Ma, Changqing ^a   Brunt, Elizabeth M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cirrhosis; congenital hepatic fibrosis; hepatoportal sclerosis; idiopathic portal hypertension; incomplete septal cirrhosis; nodular regenerative hyperplasia; noncirrhotic portal hypertension; portal hypertension

Indexed keywords

CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; DISEASE CLASSIFICATION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER FIBROSIS; PATHOPHYSIOLOGY; PORTAL HYPERTENSION; PRESSURE MEASUREMENT; PRIORITY JOURNAL; REMISSION; REVIEW; SCHISTOSOMIASIS; TISSUE STRUCTURE;

HEPATITIS, ALCOHOLIC; HUMANS; HYPERTENSION, PORTAL; LIVER; LIVER CIRRHOSIS; REMISSION, SPONTANEOUS;

EID: 84862542055     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/PAP.0b013e31825c6bab     Document Type: Review

References (81)

1. Xu J, Kochanek KD, Murphy SL, et al. Deaths: final data for 2007. Natl Vital Stat Rep. 2010;58:1-135
2. Roskams T, Baptista A, Bianchi L, et al. Histopathology of portal hypertension: a practical guideline. Histopathology. 2003;42:2-13
3. Reynolds TB, Hidemura R, Michel H, et al. Portal hypertension without cirrhosis in alcoholic liver disease. Ann Intern Med. 1969;70:497-506
4. Hodgson H, Davies D, Thompson R. Congenital hepatic fibrosis. J Clin Pathol. 1976;29:11-16
5. Wanless IR, Nakashima E, Sherman M. Regression of human cirrhosis. Arch Pathol Lab Med. 2000;124:1599-1607
6. Wanless I, Godwin T, Allen F, et al. Nodular regenerative hyperplasia of the liver in hematologic disorders: a possible response to obliterative portal venopathy. Medicine. 1980;59: 367-379
7. Bioulac-Sage P, Bail BL, Bernard P-H, et al. Hepatoportal sclerosis. Semin Liver Dis. 1995;15:329-339
8. Wanless IR. Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2500 autopsies and a new classification of benign hepatocellular nodules. Hepatology. 1990;11:787-797
9. Schouten JNL, Garcia-Pagan JC, Valla DC, et al. Idiopathic noncirrhotic portal hypertension. Hepatology. 2011;54: 1071-1081
10. Schinoni MI, Andrade Z, De Freitas LAR, et al. Incomplete septal cirrhosis: an enigmatic disease. Liver Int. 2004;24:452-456
11. Reshamwala PA, Kleiner DE, Heller T. Nodular regenerative hyperplasia: not all nodules are created equal. Hepatology. 2006;44:7-14
12. Okudaira M, Ohbu M, Okuda K. Idiopathic portal hypertension and its pathology. Semin Liver Dis. 2002;22:59-72
13. Lucas SB. Other viral and infectious diseases and HIV-related liver disease. In: Burt AD, Portmann BC, Ferrell LD, eds. MacSween's Pathology of the Liver. 5th ed. Philadelphia, PA: Churchill Livingstone; 2007:443-492
14. Dhiman RK, Chawla Y, Vasishta RK, et al. Non-cirrhotic portal fibrosis (idiopathic portal hypertension): experience with 151 patients and a review of the literature. J Gastroenterol Hepatol. 2002;17:6-16
15. Desmet VJ, Roskams T. Cirrhosis reversal: a duel between dogma and myth. J Hepatol. 2004;40:860-867
16. Anthony PP, Ishak KG, Nayak NC, et al. The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization. J Clin Pathol. 1978;31:395-414
17. Crawford JM, Burt AD. Anatomy, pathophysiology, and basic mechanisms of disease. In: Burt AD, Portmann B, Ferrell LD, eds. MacSween's Pathology of the Liver. 6th ed. Philadelphia, PA: Churchill Livingstone; 2012:1-78
18. D'Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol. 2006;44:217-231
19. Desmet VJ. Liver-non-neoplastic dieases. Rosai and Ackerman's Surgical Pathology, Vol. 1. 10th ed. Maryland Heights, MO: Mosby; 2011:857-942
20. Wanless IR, Crawford JM. Cirrhosis. In: Odze RD, Goldblum JR, eds. Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas. 2nd ed. Philadelphia, PA: Saunders; 2008:1115-1145
21. Scheuer PJ, Lefkowitch JH. Cirrhosis. Liver Biopsy Interpretation. 7th ed. Philadelphia, PA: Saunders Ltd.; 2005:171-190
22. Albilllos A, Garcia-Tsao G. Classification of cirrhosis: the clinical use of HVPG measurements. Dis Markers. 2011;31: 121-128
23. Boyer TD. Portal hypertension and bleeding esophageal varices. In: Boyer TD, Wright TL, Manns MP, eds. Hepatology: A Textbook of Liver Disease, Vol. 1. 5th ed. Philadelphia, PA: Saunders; 2006:347-382
24. Thalheimer U, Leandro G, Samonakis DN, et al. Assessment of the agreement between wedge hepatic vein pressure and portal vein pressure in cirrhotic patients. Dig Liver Dis. 2005;37:601-608
25. Groszmann R, Vorobioff JD, Gao H. Measurement of portal pressure: when, how, and why to do it. Clin Liver Dis. 2006;10: 499-512
26. Bosch J, Abraldes JG, Berzigotti A, et al. The clinical use of HVPG measurements in chronic liver disease. Nat Rev Gastroenterol Hepatol. 2009;6:573-582
27. Escorsell A , Bru C, Gilabert R, et al. Wedged hepatic venous pressure adequately reflects portal pressure in hepatitis C virusrelated cirrhosis. Hepatology. 1999;30:1393-1397
28. Ripoll C, Groszmann RJ, Garcia-Tsao G, et al. Hepatic venous pressure gradient predicts development of hepatocellular carcinoma independently of severity of cirrhosis. J Hepatol. 2009;50:923-928
29. Scheuer PJ, Lefkowitch JH. Biliary disease. Liver Biopsy Interpretation. 7th ed. Philadelphia, PA: Saunders; 2005:53-84
30. Goodman ZD, Ishak KG. Occlusive venous lesions in alcoholic liver disease. Gastroenterology. 1985;83:786-796
31. Brunt EM. Alcoholic and nonalcoholic steatohepatitis. Clin Liver Dis. 2002;6:399-420
32. De Cock K. Hepatosplenic schistosomiasis: a clinical review. Gut. 1986;27:734-745
33. Lucas SB, Zaki SR, Portmann B. Other viral and infectious diseases and HIV-related liver disease. In: Burt AD, Portmann BC, Ferrell LD, eds. MacSween's Pathology of the Liver. 6th ed. Philadelphia, Pennsylvania: Churchill Livingstone; 2012:403-466
34. CDC-Schistosomiasis. http://www.cdc.gov/parasites/schistoso miasis/index.html. Accessed March 31, 2012
35. Vargas-Tank L, Martinez V, Jiró n MI, et al. Tru-cut and Menghini needles: different yield in the histological diagnosis of liver disease. Liver. 1985;5:178-181
36. Kalambokis G, Manousou P, Vibhakorn S, et al. Transjugular liver biopsy-indications, adequacy, quality of specimens, and complications-a systematic review. J Hepatol. 2007;47: 284-294
37. Colombo M, Del Ninno E, de Franchis R, et al. Ultrasoundassisted percutaneous liver biopsy: superiority of the Tru-Cut over the Menghini needle for diagnosis of cirrhosis. Gastroenterology. 1988;95:487-489
38. Kojiro M, Roskams T. Early hepatocellular carcinoma and dysplastic nodules. Semin Liver Dis. 2005;25:133-142
39. Deugnier YM, Charalambous P, Quilleuc DL, et al. Preneoplastic significance of hepatic iron-free foci in genetic hemochromatosis: a study of 185 patients. Hepatology. 1993;18: 1363-1369
40. Hytiroglou P, Park YN, Krinsky G, et al. Hepatic precancerous lesions and small hepatocellular carcinoma. Gastroenterol Clin North Am. 2007;36:867-887, vii
41. Dienes H, Drebber U, von Both I. Liver biopsy in hepatitis C. J Hepatol. 1999;31(SUPPL. 1):43-46
42. Mani H, Kleiner DE. Liver biopsy findings in chronic hepatitis B. Hepatology. 2009;49(S5):S61-S71
43. Lefkowitch J, Mendez L. Morphologic features of hepatic injury in cardiac disease and shock. J Hepatol. 1986;2: 313-327
44. Caldwell SH, Oelsner DH, Iezzoni JC, et al. Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease. Hepatology. 1999;29:664-669
45. Brunt EM. Pathology of nonalcoholic steatohepatitis. Hepatology Research. 2005;33:68-71
46. Ku N-O, Gish R, Wright TL, et al. Keratin 8 Mutations in Patients with Cryptogenic Liver Disease. N Engl J Med. 2001;344:1580-1587
47. Ku N, Wright T, Terrault N, et al. Mutation of human keratin 18 in association with cryptogenic cirrhosis. J Clin Invest. 1997;99:19-23
48. De Vos M, Barbier F, Cuvelier C. Congenital hepatic fibrosis. J Hepatol. 1988;6:222-228
49. Portmann BC, Roberts EA. Developmental abnormalities and liver disease in childhood. In: Burt AD, Portmann BC, Ferrell LD, eds. MacSween's Pathology of the Liver, Sixth edn, Vol. 6th ed. Philadelphia, Pennsylvania: Churchill Livingstone; 2012:126-127
50. Schiano TD, Kotler DP, Ferran E, et al. Hepatoportal sclerosis as a cause of noncirrhotic portal hypertension in patients with HIV. Am J Gastroenterol. 2007;102:2536-2540
51. Hillaire S, Bonte E, Denninger M-H, et al. Idiopathic noncirrhotic intrahepatic portal hypertension in the West: a reevaluation in 28 patients. Gut. 2002;51:275-280
52. Sciot R, Staessen D, Van Damme B, et al. Incomplete septal cirrhosis: Histopathological aspects. Histopathology. 1988;13: 593-603
53. Rougier P, Degott C, Rueff B, et al. Nodular regenerative hyperplasia of the liver. Report of six cases and review of the literature. Gastroenterology. 1978;75:169-172
54. Williams R. Global challenges in liver disease. Hepatology. 2006;44:521-526
55. Lefkowitch JH. Morphology of Alcoholic Liver Disease. Clin Liv Dis. 2005;9:37-53
56. Goodman Z, Ishak K. Occlusive venous lesions in alcoholic liver disease. A study of 200 cases. Gastroenterology. 1982;83: 786-796
57. Chawla Y, Dhiman RK. Intrahepatic Portal Venopathy and Related Disorders of the Liver. Semin Liver Dis. 2008;28: 270,81
58. Hillaire S, Valla D, Lebrec D. Noncirrhotic portal hypertension. Clin Liver Dis. 1997;1:223-240
59. Madhu K, Avinash B, Ramakrishna B, et al. Idiopathic non-cirrhotic intrahepatic portal hypertension: common cause of cryptogenic intrahepatic portal hypertension in a Southern Indian tertiary hospital. Indian J Gastroenterol. 2009; 28:83-87
60. Nakanuma Y, Sato Y, Kiktao A. Pathology and pathogenesis of portal venopathy in idiopathic portal hypertension: Hints from systemic sclerosis. Hepatology Research. 2009;39: 1023-1031
61. DeLeve LD. Hepatic Microvasculature in Liver Injury. Semin Liver Dis. 2007;27:390, 400
62. Dubinsky MC, Vasiliauskas EA, Singh H, et al. 6-thioguanine can cause serious liver injury in inflammatory bowel disease patients. Gastroenterology. 2003;125:298-303
63. Haboubi N, Ali H, Whitwell H, et al. Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: light microscopy and ultrastructural observations. Am J Gastroenterol. 1988;83: 256-261
64. Arotçarena R, Calè s V, Berthelémy P, et al. Severe sinusoidal lesions: a serious and overlooked complication of oxaliplatincontaining chemotherapy? Gastroenterol Clin Biol. 2006;30: 1313-1316
65. Vispo E, Morello J, Rodriguez-Novoa S, et al. Noncirrhotic portal hypertension in HIV infection. Curr Opin Infect Dis. 2011;24:12-18
66. Goel A, Ramakrishna B, Madhu K, et al. Idiopathic noncirrhotic intrahepatic portal hypertension is an ongoing problem in India. Hepatology. 2011;54:2275-2276
67. Shiratori Y, Imazeki F, Moriyama M, et al. Histologic Improvement of Fibrosis in Patients with Hepatitis C Who Have Sustained Response to Interferon Therapy. Ann Internal Med. 2000;132:517-524
68. Poynard T, McHutchison J, Manns M, et al. Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology. 2002;122: 1303-1313
69. Pol S, Carnot F, Nalpas B, et al. Reversibility of hepatitis C virus-related cirrhosis. Human Pathology. 2004;35:107-112
70. Hammel P, Couvelard A, O'Toole D, et al. Regression of Liver Fibrosis after Biliary Drainage in Patients with Chronic Pancreatitis and Stenosis of the Common Bile Duct. N Engl J Med. 2001;344:418-423
71. Falize L, Guillygomarc'h A, Perrin M, et al. Reversibility of hepatic fibrosis in treated genetic hemochromatosis: A study of 36 cases. Hepatology. 2006;44:472-477
72. Chang T-T, Liaw Y-F, Wu S-S, et al. Long-term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B. Hepatology. 2010;52:886-893
73. Wanless IR. Pathogenesis of cirrhosis. J Gastroenterol and Hepatol. 2004;19:S369-S371
74. Guyot C, Lepreux S, Combe C, et al. Hepatic fibrosis and cirrhosis: The (myo)fibroblastic cell subpopulations involved Int J Biochem Cell Biol. 2006; 38: 135-151
75. Iredale JP. Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J Clin Invest. 2007;117:539-548
76. Desmet VJ. Comments on cirrhosis reversal. Digestive and Liver Disease. 2005;37:909-916
77. Issa R, Zhou X, Constandinou CM, et al. Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology. 2004;126:1795-1808
78. Garcia-Tsao G, Friedman S, Iredale J, et al. Now there are many (stages) where before there was one: In search of a pathophysiological classification of cirrhosis. Hepatology. 2010;51:1445-1449
79. Kutami R, Girgrah N, Wanless IR, et al. The Laennec grading system for assessment of hepatic fibrosis: validation by correlation with wedged hepatic vein pressure and clinical features [abstract]. Hepatology. 2000;32:407A
80. Nagula S, Jain D, Groszmann RJ, et al. Histologicalhemodynamic correlation in cirrhosis-a histological classification of the severity of cirrhosis. J Hepatol. 2006;44: 111-117
81. Hytiroglou P, Snover DC, Alves V, et al. Beyond Cirrhosis. Am J Clin Pathol. 2012;137:5-9