Histopathology of portal hypertension: A practical guideline

Histopathology

Volumn 42, Issue 1, 2003, Pages 2-13

  Roskams, Tania ^a,l   Baptista, A ^b   Bianchi, L ^c   Burt, A ^d   Callea, F ^e   Denk, H ^f   De Groote, J ^a   Desmet, V ^a   Hubscher, S ^g   Ishak, K ^h   MacSween, R ⁱ   Portmann, B ^j   Poulson, H ^m   Scheuer, P ^k   Terracciano, L ^c   Thaler, H ^m  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b HOSPITAL DE SANTA MARIA   (Portugal)

^c UNIVERSITY OF BASEL   (Switzerland)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e SPEDALI CIVILI   (Italy)

^f UNIVERSITY OF GRAZ   (Austria)

^g UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^h ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

ⁱ UNIVERSITY OF GLASGOW   (United Kingdom)

^j KING'S COLLEGE LONDON   (United Kingdom)

^k ROYAL FREE HOSPITAL   (United Kingdom)

^l UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^m NONE

more..

Author keywords

Hepatoportal sclerosis; Idiopathic portal hypertension; Incomplete septal cirrhosis; Nodular regenerative hyperplasia; Non cirrhotic portal hypertension; Partial nodular transformation; Portal hypertension

Indexed keywords

ALPHA ACTIN; AMIODARONE; ARSENIC; AZATHIOPRINE; METHOTREXATE; PERHEXILINE MALEATE; VINYL CHLORIDE;

ALCOHOL LIVER CIRRHOSIS; BLOOD VESSEL INJURY; CENTRAL VENOUS PRESSURE; DIAGNOSTIC IMAGING; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DRUG INDUCED DISEASE; EXTRAPULMONARY TUBERCULOSIS; GAUCHER DISEASE; HEART CATHETERIZATION; HISTOPATHOLOGY; HUMAN; LIVER ATROPHY; LIVER BLOOD FLOW; LIVER CELL DAMAGE; LIVER CIRRHOSIS; LIVER CONGESTION; LIVER FIBROSIS; LIVER HYPERPLASIA; LIVER PARENCHYMA; LIVER SINUSOID; MALLORY BODY; MYELOID METAPLASIA; NEEDLE BIOPSY; NONHUMAN; PORTAL HYPERTENSION; PORTAL VEIN OBSTRUCTION; PORTAL VEIN THROMBOSIS; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; RENDU OSLER WEBER DISEASE; REVIEW; SARCOIDOSIS; SCHISTOSOMIASIS; SYSTEMIC MASTOCYTOSIS; SYSTEMIC VASCULAR RESISTANCE; VENOUS STASIS; VIRUS HEPATITIS;

HUMANS; HYPERTENSION, PORTAL; LIVER CIRCULATION; LIVER CIRRHOSIS; MICROCIRCULATION; PRACTICE GUIDELINES;

EID: 12244310799     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.2003.01464.x     Document Type: Review

References (67)

1. Boyer T. Portal hypertension and bleeding esophageal varices. In Zakim D, Boyer T eds. Hepatology, a textbook of liver disease, 2nd edn. Philadelphia: Saunders, 1990; 572-615.
2. Lebrec D. Hepatic vein catheterization. In Okuda K, Benhamou J-P eds. Portal Hypertension: Clinical and Physiological Aspects. Tokyo: Springer-Verlag, 1991; 117-125.
3. Benhamou J-P, Valla D. Intrahepatic portal hypertension. In Bircher J, Benhamou J-P, McIntyre N, Rizzetto M, Rodes J eds. Oxford textbook of clinical hepatology. Oxford: Oxford University Press, 1999; 661-669.
4. Wanless I. Vascular disorders. In McSween R, Anthony P, Scheuer P, Burt A, Portmann B eds. Pathology of the Liver. New York: Churchill Livingstone, 1994; 535-562.
5. Okuda K, Kono K, Ohnishi K, Kimura K, Omata M, Koen H et al. Clinical study of eighty-six cases of idiopathic portal hypertension and comparison with cirrhosis with splenomegaly. Gastroenterology 1984; 86; 600-610.
6. Sarin S. Non-cirrhotic portal hypertension. In Bosch J, Groszmann R eds. Portal hypertension: Pathophysiology and treatment. Oxford: Blackwell, 1994; 27-53.
7. Ludwig J, Hashimoto E, Obata H, Baldus W. Idiopathic portal hypertension. A histopathological study of 26 Japanese cases. Histopathology 1993; 22; 227-234.
8. Nayak N. Pathology of non-cirrhotic portal fibrosis of India. In Okuda K, Omata M eds. Idiopathic Portal Hypertension. Tokyo: University of Tokyo Press, 1983; 37-47.
9. Mikkelsen WP, Edmondson HA, Peters RL, Redeker AG, Reynolds TR. Extra- and intrahepatic portal hypertension without cirrhosis (hepatoportal sclerosis). Ann. Surg. 1965; 162; 602-620.
10. Wanless I, Peterson P, Das A, Boitnott J, Moore G, Bernier V. Hepatic vascular disease and portal hypertension in polycythemia vera and agnogenic myeloid metaplasia. A clinicopathological study of 145 patients examined at autopsy. Hepatology 1990; 12; 1166-1174.
11. Anthony PP, Ishak KG, Nayak NC, Poulsen HE, Scheuer P, Sobin LH. The morphology of cirrhosis. J. Clin. Pathol. 1978; 31; 395-414.
12. Mak KM, Lieber CS. Alterations in endothelial fenestrations in liver sinusoids of baboons fed alcohol: a scanning electron microscopic study. Hepatology 1984; 4; 386-391.
13. Zimmerman H, Lewis J, Kassianides C. Cirrhosis. In Okuda K, Benhamou J-P eds. Portal Hypertension: Clinical and Physiological Aspects. Tokyo: Springer-Verlag, 1991; 251-270.
14. Kelty R, Baggenstoss A, Butt H. The relation of the regenerated liver nodule to the vascular bed in cirrhosis. Gastroenterology 1950; 15; 285-295.
15. McIndoe A. Vascular lesions of portal cirrhosis. Arch. Pathol. Lab. Med. 1928; 5; 23-40.
16. Picchiotti R, Mingazzini P, Scucchi L. Correlation between sinusoidal pressure and liver morphology in cirrhosis. J. Hepatol. 1994; 20; 364-369.
17. Popper H, Elias H, Petty DE. Vascular patterns of the cirrhotic liver. Am. J. Clin. Pathol. 1952; 22; 717-729.
18. Krogsgaard K, Christensen E, Gluud C, Henriksen J, Christoffer-sen P. Variables predicting elevated portal pressure in alcoholic liver disease. Results of a multivariate analysis. Scand. J. Gastroenterol. 1987; 22; 82-86.
19. Le Bail B, Bioulac-Sage P, Senuita R, Quinton A, Saric J, Balabaud C. Fine structure of hepatic sinusoids and sinusoidal cells in disease. J. Electron. Microsc. Tech. 1990; 14; 257-282.
20. Schaffner F, Popper H. Capillarization of hepatic sinusoids in man. Gastroenterology 1963; 44; 239-242.
21. Bhunchet E, Fujieda K. Capillarization and venularization of hepatic sinusoids on porcine serum-induced rat liver fibrosis: A mechanism to maintain liver blood flow. Hepatology 1993; 18; 1450-1458.
22. Desmet VJ. Fibrosis of the Liver: A Pathologist's View. Dordrecht: Kluwer Academic Publishers, 1994.
23. Gaudio E, Pannarale L, Onori P, Riggio O. A scanning electron microscopic study of liver microcirculation disarrangement in experimental rat cirrhosis. Hepatology 1993; 17; 477-485.
24. Nakanuma Y, Ohta G, Doishita K. Quantitation and serial section observations of focal venocclusive lesions of hepatic veins in liver cirrhosis. Virchows Arch. (A) 1985; 405; 429-438.
25. Wanless I. Secondary portal and hepatic vein thrombosis in cirrhosis: A quantative study. Hepatology 1994; 19; 1391.
26. Popper H. What are the Major Types of Hepatic Cirrhosis? Philadelphia: W.B. Saunders, 1966.
27. Sciot R., Staessen D, Van Damme B, Van Steenbergen W, Fevery J, De Groote J et al. Incomplete septal cirrhosis: Histopathological aspects. Histopathology 1988; 13; 593-603.
28. Nevens F, Staessen D, Sciot R, Van Damme B, Desmet V, Fevery J. Clinical aspects of incomplete septal cirrhosis in comparison with macronodular cirrhosis. Gastroenterology 1994; 106; 459-463.
29. Sciot R, Van Damme B, Desmet V. Does incomplete septal cirrhosis link non-cirrhotic nodulations with cirrhosis? Histopathology 1989; 15; 318-320.
30. Desmet VJ, Sciot R, Van Eyken P. Differential diagnosis and prognosis of cirrhosis: Role of liver biopsy. Acta Gastroenterol. Belg. 1990; 53; 198-208.
31. Barnett J, Appelmans H, Moseley R. A familial form of incomplete septal cirrhosis. Gastroenterology 1992; 102; 674-678.
32. Ohbu M, Okudaira M, Watanabe K et al. Histopathological study of intrahepatic aberrant vessels in cases of non-cirrhotic portal hypertension. Hepatology 1994; 20; 302-308.
33. Bioulac-Sage P, Le Bail B, Bernard P, Balabaud C. Hepatoportal sclerosis. Seminars Liver Dis. 1995; 15; 329-339.
34. Masuda T, Oikawa H, Sato S, Satodate S, Suzuki S, Sato S. Distinguishing small lymph vessels in the portal tracts of human liver from portal veins by immunohistochemistry for alpha smooth muscle actin. Int. Hepatol. Commun. 1996; 4; 277-282.
35. Oikawa H, Masuda T, Sato S-I, Yashima A, Suzuki K, Sato S et al. Changes in lymph vessels and portal veins in the portal tract of patients with idiopathic portal hypertension: A morphometric study. Hepatology 1998; 27; 1607-1610.
36. Nakanuma Y, Hoso M, Sasaki M, Terada T, Katayanagi K, Nonomura A et al. Histopathology of the liver in non-cirrhotic portal hypertension of unknown etiology. Histopathology 1996; 28; 195-204.
37. Siderys H, Judd D, Herendeen T. The experimental production of elevated portal pressure by increasing portal vein flow. Surg. Gynecol. Obstet. 1965; 120; 514-516.
38. Malmqvist U. Effects of long-term portal hypertension on structure, active force and content of contractile and structural proteins in smooth muscle of the rat portal vein. Acta Physiol. Scand. 1994; 150; 171-179.
39. Nio M, Takahashi T, Ohi R. Changes of intrahepatic portal veins in biliary atresia: Formation and development of medial smooth muscles correlated with portal hypertension. In Ohi R ed. Biliary Atresia. Tokyo: Professional Postgraduate Services, 1987; 243-250.
40. Cohen J, Edelman R., Chopra S. Portal vein thrombosis: A review. Am. J. Med. 1992; 92; 173-182.
41. Bernard O, Alvarez F, Brunelle F, Hadchouel P, Allagille D. Portal hypertension in children. Clin. Gastroenterol. 1985; 14; 33-55.
42. Wanless I. Pathology of non-cirrhotic portal hypertension. In Okuda K, Benhamou J-P eds. Portal Hypertension: Clinical and Physiological Aspects. Tokyo: Springer-Verlag, 1991; 393-399.
43. Wanless IR. Micronodular transformation (nodular regenerative hyperplasia) of the liver. A report of 64 cases among 2.500 autopsies and a new classification of benign hepatocellular nodules. Hepatology 1990; 11; 787-797.
44. Kobayashi S, Nakanuma Y, Matsui O. Histopathology of portal tracts in livers after transcatheter arterial chemo-embolization therapy for hepatocellular carcinoma. J. Gastroenterol. Hepatol. 1993; 9; 45-54.
45. Sherlock S, Feldman CA, Moran B, Scheuer PJ. Partial nodular transformation of the liver with portal hypertension. Am. J. Med. 1966; 40; 195-203.
46. Fukuda K, Kage M, Arakawa M, Nakashima T. Portal vein or hepatic vein? A curious aberrant vasculature in the liver with idiopathic portal hypertension. Acta Pathol. Jpn. 1985; 35; 885-897.
47. Ishak K. Nodular regenerative hyperplasia, blood disorders and other uncommon diseases associated with intrahepatic portal hypertension. In Okuda K, Benhamou J-P eds. Portal Hypertension: Clinical and Physiological Aspects. Tokyo: Springer-Verlag, 1991; 325-342.
48. Wanless IR. The Pathophysiology of Non-cirrhotic Portal Hypertension: A Pathologist's Perspective. Lancaster: MTP Press, 1987.
49. International Working Party. Terminology of nodular hepatocellular lesions. Hepatology 1995; 22; 983-993.
50. Stromeyer FW, Ishak KG. Nodular transformation (nodular 'regenerative' hyperplasia) of the liver. A clinicopathologic study of 30 cases. Hum. Pathol. 1981; 12; 60-71.
51. Melkebeke P, Vandepitte J, Hannon R, Fevery J. Huge hepatomegaly, jaundice, and portal hypertension due to amyloidosis of the liver. Digestion 1980; 20; 351-357.
52. Bedossa P, Fabre M, Paraf F, Martin E, Lamaigre G. Light chain deposition disease with liver dysfunction. Hum. Pathol. 1988; 19; 1008-1014.
53. Horn T, Christofferson P. Sinusoidal endothelial cells: A SEM investigation of the fenestration in normal and diseased human liver. In Bioulac-Sage P, Balabaud C eds. Sinusoids in Human Liver: Health and Disease. Rijswijk: Kupffer Cell Foundation, 1988; 189-206.
54. Grundfest S, Cooperman A, Ferguson R. Portal hypertension associated with systemic mastocytosis and splenomegaly. Gastroenterology 1980; 78; 370-373.
55. Roux D, Merlio J, Quinton A, Lamouliatte H, Balabaud C, Bioulac-Sage P. Agnogenic myeloid metaplasia, portal hypertension and sinusoidal abnormalities. Gastroenterology 1987; 92; 1067-1072.
56. James S, Stromeyer F, Cheng C, Barranger J. Liver abnormalities in patients with Gaucher's disease. Gastroenterology 1981; 80; 126-133.
57. Wanless IR, Godwin TA, Allen F, Feder A. Nodular regenerative hyperplasia of the liver in hematologic disorders: A possible response to obliterative portal venopathy. Medicine 1980; 59; 367-379.
58. Bearman S. The syndrome of hepatic veno-occlusive disease after marrow transplantation. Blood 1995; 85; 3005-3020.
59. Shulman H, Fisher L, Schoch H et al. Venoocclusive disease of the liver after marrow transplantation: Histological correlates of clinical signs and symptoms. Hepatology 1994; 19; 1171-1180.
60. Shulman H, Gown A, Nugent D. Hepatic veno-occlusive disease after bone marrow transplantation. Immunohistochemical identification of the material within occluded central venules. Am. J. Pathol. 1987; 127; 549-558.
61. Ishak KG, Zimmerman HJ, Ray MB. Alcoholic liver disease: Pathologic, pathogenetic and clinical aspects. Alcohol Clin. Exp. Res. 1991; 15; 45-66.
62. Denk H, Scheuer PJ, Baptista A, Bianchi L, Callea F, De Groote J et al. Guidelines for the diagnosis and interpretation of hepatic granulomas. Histopathology 1994; 25; 209-218.
63. Kage M, Nakashima T. The pathology of Schistosomiasis. In Okuda K, Benhamou J-P eds. Portal Hypertension: Clinical and Physiological Aspects. Tokyo: Springer-Verlag, 1991; 289-299.
64. Desmet VJ. Congenital diseases of intrahepatic bile ducts: Variations on the theme 'ductal plate malformation'. Hepatology 1992; 16; 1069-1083.
65. Desmet VJ. What is congenital hepatic fibrosis? Histopathology 1992; 20; 465-477.
66. Wanless I, Gryfe A. Nodular transformation of the liver in hereditary hemorrhagic telangiectasia. Arch. Pathol. Lab. Med. 1986; 110; 331-335.
67. Daly J, Schiller A. The liver in hemorrhagic telangiectasia (Osler-Rendu disease). Am. J. Med. 1976; 60; 723-726.