-
1
-
-
0019918172
-
New perspectives on the microvasculature of the islets of Langerhans in the rat
-
Bonner-Weir S, Orci L (1982) New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes 31: 883-889
-
(1982)
Diabetes
, vol.31
, pp. 883-889
-
-
Bonner-Weir, S.1
Orci, L.2
-
2
-
-
55849102524
-
Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets
-
Nyman LR, Wells KS, Head WS et al (2008) Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets. J Clin Invest 118: 3790-3797
-
(2008)
J Clin Invest
, vol.118
, pp. 3790-3797
-
-
Nyman, L.R.1
Wells, K.S.2
Head, W.S.3
-
3
-
-
0035913986
-
Induction of pancreatic differentiation by signals from blood vessels
-
Lammert E, Cleaver O, Melton D (2001) Induction of pancreatic differentiation by signals from blood vessels. Science 294: 564-567
-
(2001)
Science
, vol.294
, pp. 564-567
-
-
Lammert, E.1
Cleaver, O.2
Melton, D.3
-
4
-
-
33644537403
-
The vascular basement membrane: A niche for insulin gene expression and beta cell proliferation
-
Nikolova G, Jabs N, Konstantinova I et al (2006) The vascular basement membrane: a niche for insulin gene expression and beta cell proliferation. Dev Cell 10: 397-405
-
(2006)
Dev Cell
, vol.10
, pp. 397-405
-
-
Nikolova, G.1
Jabs, N.2
Konstantinova, I.3
-
5
-
-
70349866705
-
Endothelial cell signalling supports pancreatic beta cell function in the rat
-
Johansson A, Lau J, Sandberg M, Borg LA, Magnusson PU, Carlsson PO (2009) Endothelial cell signalling supports pancreatic beta cell function in the rat. Diabetologia 52: 2385-2394
-
(2009)
Diabetologia
, vol.52
, pp. 2385-2394
-
-
Johansson, A.1
Lau, J.2
Sandberg, M.3
Borg, L.A.4
Magnusson, P.U.5
Carlsson, P.O.6
-
6
-
-
80052081270
-
Thrombospondin-1: An islet endothelial cell signal of importance for {beta}-cell function
-
Olerud J, Mokhtari D, JohanssonM et al (2011) Thrombospondin-1: an islet endothelial cell signal of importance for {beta}-cell function. Diabetes 60: 1946-1954
-
(2011)
Diabetes
, vol.60
, pp. 1946-1954
-
-
Olerud, J.1
Johanssonm, M.D.2
-
7
-
-
33645860514
-
Islet endothelial cells and pancreatic beta-cell proliferation: Studies in vitro and during pregnancy in adult rats
-
Johansson M, Mattsson G, Andersson A, Jansson L, Carlsson PO (2006) Islet endothelial cells and pancreatic beta-cell proliferation: studies in vitro and during pregnancy in adult rats. Endocrinology 147: 2315-2324
-
(2006)
Endocrinology
, vol.147
, pp. 2315-2324
-
-
Johansson, M.1
Mattsson, G.2
Andersson, A.3
Jansson, L.4
Carlsson, P.O.5
-
8
-
-
0004808355
-
Microcirculation of the islets of Langerhans. Long beach veterans administration regional medical education center symposium
-
Brunicardi FC, Stagner J, Bonner-Weir S et al (1996) Microcirculation of the islets of Langerhans. Long beach veterans administration regional medical education center symposium. Diabetes 45: 385-392
-
(1996)
Diabetes
, vol.45
, pp. 385-392
-
-
Brunicardi, F.C.1
Stagner, J.2
Bonner-Weir, S.3
-
9
-
-
33845540482
-
Pancreatic islet production of vascular endothelial growth factor - A is essential for islet vascularization, revascularization, and function
-
Brissova M, Shostak A, Shiota M et al (2006) Pancreatic islet production of vascular endothelial growth factor-a is essential for islet vascularization, revascularization, and function. Diabetes 55: 2974-2985
-
(2006)
Diabetes
, vol.55
, pp. 2974-2985
-
-
Brissova, M.1
Shostak, A.2
Shiota, M.3
-
10
-
-
0029785719
-
Microsphere distribution in the pancreas of anesthetized rats. Alloxan stimulates the blood flow to all islets whereas glucose only affects the blood perfusion of a subgroup of islets
-
Jansson L (1996) Microsphere distribution in the pancreas of anesthetized rats. Alloxan stimulates the blood flow to all islets whereas glucose only affects the blood perfusion of a subgroup of islets. Int J Pancreatol 20: 69-74
-
(1996)
Int J Pancreatol
, vol.20
, pp. 69-74
-
-
Jansson, L.1
-
11
-
-
11244340659
-
Multiple injections of coloured microspheres for islet blood flow measurements in anaesthetised rats: Influence of microsphere size
-
Carlsson PO, Kallskog O, Bodin B, Andersson A, Jansson L (2002) Multiple injections of coloured microspheres for islet blood flow measurements in anaesthetised rats: influence of microsphere size. Ups J Med Sci 107: 111-120
-
(2002)
Ups J Med Sci
, vol.107
, pp. 111-120
-
-
Carlsson, P.O.1
Kallskog, O.2
Bodin, B.3
Andersson, A.4
Jansson, L.5
-
12
-
-
0030952821
-
Islet capillary blood pressure increase mediated by hyperglycemia in NIDDM GK rats
-
Carlsson PO, Jansson L, Ostenson CG, Kallskog O (1997) Islet capillary blood pressure increase mediated by hyperglycemia in NIDDM GK rats. Diabetes 46: 947-952
-
(1997)
Diabetes
, vol.46
, pp. 947-952
-
-
Carlsson, P.O.1
Jansson, L.2
Ostenson, C.G.3
Kallskog, O.4
-
13
-
-
0036710409
-
Glucose-induced islet blood flow increase in rats: Interaction between nervous and metabolic mediators
-
Carlsson PO, Olsson R, Kallskog O, Bodin B, Andersson A, Jansson L (2002) Glucose-induced islet blood flow increase in rats: interaction between nervous and metabolic mediators. Am J Physiol Endocrinol Metab 283: E457-E464
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
Carlsson, P.O.1
Olsson, R.2
Kallskog, O.3
Bodin, B.4
Andersson, A.5
Jansson, L.6
-
15
-
-
0020570005
-
Stimulation by glucose of the blood flow to the pancreatic islets of the rat
-
Jansson L, Hellerstrom C (1983) Stimulation by glucose of the blood flow to the pancreatic islets of the rat. Diabetologia 25: 45-50
-
(1983)
Diabetologia
, vol.25
, pp. 45-50
-
-
Jansson, L.1
Hellerstrom, C.2
-
16
-
-
0016354383
-
Effects of glucose on the ultrastructure and insulin biosynthesis of isolated mouse pancreatic islets maintained in tissue culture
-
Andersson A, Westman J, Hellerstrom C (1974) Effects of glucose on the ultrastructure and insulin biosynthesis of isolated mouse pancreatic islets maintained in tissue culture. Diabetologia 10: 743-753
-
(1974)
Diabetologia
, vol.10
, pp. 743-753
-
-
Andersson, A.1
Westman, J.2
Hellerstrom, C.3
-
18
-
-
0025336496
-
Binding of human endothelium to Ulex europaeus I-coated Dynabeads: Application to the isolation of microvascular endothelium
-
Jackson CJ, Garbett PK, Nissen B, Schrieber L (1990) Binding of human endothelium to Ulex europaeus I-coated Dynabeads: application to the isolation of microvascular endothelium. J Cell Sci 96 (Pt 2): 257-262
-
(1990)
J Cell Sci
, vol.96 PART. 2
, pp. 257-262
-
-
Jackson, C.J.1
Garbett, P.K.2
Nissen, B.3
Schrieber, L.4
-
19
-
-
33645856011
-
Endothelial cells in endogenous and transplanted pancreatic islets: Differences in the expression of angiogenic peptides and receptors
-
Mattsson G, Danielsson A, Kriz V, Carlsson PO, Jansson L (2006) Endothelial cells in endogenous and transplanted pancreatic islets: differences in the expression of angiogenic peptides and receptors. Pancreatology 6: 86-95
-
(2006)
Pancreatology
, vol.6
, pp. 86-95
-
-
Mattsson, G.1
Danielsson, A.2
Kriz, V.3
Carlsson, P.O.4
Jansson, L.5
-
20
-
-
23644443845
-
Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts
-
Nyqvist D, Kohler M, Wahlstedt H, Berggren PO (2005) Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts. Diabetes 54: 2287-2293
-
(2005)
Diabetes
, vol.54
, pp. 2287-2293
-
-
Nyqvist, D.1
Kohler, M.2
Wahlstedt, H.3
Berggren, P.O.4
-
21
-
-
0016135091
-
Long-term effects of glucose on insulin release and glucose oxidation by mouse pancreatic islets maintained in tissue culture
-
Andersson A (1974) Long-term effects of glucose on insulin release and glucose oxidation by mouse pancreatic islets maintained in tissue culture. Biochem J 140: 377-382
-
(1974)
Biochem J
, vol.140
, pp. 377-382
-
-
Andersson, A.1
-
22
-
-
0037665295
-
Role of VEGF-A in vascularization of pancreatic islets
-
Lammert E, Gu G, McLaughlin M et al (2003) Role of VEGF-A in vascularization of pancreatic islets. Curr Biol 13: 1070-1074
-
(2003)
Curr Biol
, vol.13
, pp. 1070-1074
-
-
Lammert, E.1
Gu, G.2
McLaughlin, M.3
-
23
-
-
32944474182
-
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
-
Kamba T, Tam BY, Hashizume H et al (2006) VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 290: H560-H576
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Kamba, T.1
Tam, B.Y.2
Hashizume, H.3
-
24
-
-
0347995018
-
VEGF (121) and VEGF(165) regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model
-
Nakatsu MN, Sainson RC, Perez-del-Pulgar S et al (2003) VEGF (121) and VEGF(165) regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model. Lab Invest 83: 1873-1885
-
(2003)
Lab Invest
, vol.83
, pp. 1873-1885
-
-
Nakatsu, M.N.1
Sainson, R.C.2
Perez-Del-Pulgar, S.3
-
25
-
-
44749086106
-
Blood vessels of human islets of Langerhans are surrounded by a double basement membrane
-
Virtanen I, Banerjee M, Palgi J et al (2008) Blood vessels of human islets of Langerhans are surrounded by a double basement membrane. Diabetologia 51: 1181-1191
-
(2008)
Diabetologia
, vol.51
, pp. 1181-1191
-
-
Virtanen, I.1
Banerjee, M.2
Palgi, J.3
-
26
-
-
77954848215
-
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
-
Marcheva B, Ramsey KM, Buhr ED et al (2010) Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature 466: 627-631
-
(2010)
Nature
, vol.466
, pp. 627-631
-
-
Marcheva, B.1
Ramsey, K.M.2
Buhr, E.D.3
-
27
-
-
70349145464
-
Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas
-
Du A, Hunter CS, Murray J et al (2009) Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas. Diabetes 58: 2059-2069
-
(2009)
Diabetes
, vol.58
, pp. 2059-2069
-
-
Du, A.1
Hunter, C.S.2
Murray, J.3
-
28
-
-
0026651708
-
Heterogeneity in pancreatic beta-cell population
-
Pipeleers DG (1992) Heterogeneity in pancreatic beta-cell population. Diabetes 41: 777-781
-
(1992)
Diabetes
, vol.41
, pp. 777-781
-
-
Pipeleers, D.G.1
-
29
-
-
0028095283
-
Physiologic relevance of heterogeneity in the pancreatic beta-cell population
-
Pipeleers D, Kiekens R, Ling Z, Wilikens A, Schuit F (1994) Physiologic relevance of heterogeneity in the pancreatic beta-cell population. Diabetologia 37(Suppl 2): S57-S64
-
(1994)
Diabetologia
, vol.37
, Issue.SUPPL. 2
-
-
Pipeleers, D.1
Kiekens, R.2
Ling, Z.3
Wilikens, A.4
Schuit, F.5
-
30
-
-
80052839471
-
A low-oxygenated subpopulation of pancreatic islets constitutes a functional reserve of endocrine cells
-
Olsson R, Carlsson PO (2011) A low-oxygenated subpopulation of pancreatic islets constitutes a functional reserve of endocrine cells. Diabetes 60: 2068-2075
-
(2011)
Diabetes
, vol.60
, pp. 2068-2075
-
-
Olsson, R.1
Carlsson, P.O.2
-
31
-
-
79953294165
-
Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro
-
Sato Y, Endo H, Okuyama H et al (2011) Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro. J Biol Chem 286: 12524-12532
-
(2011)
J Biol Chem
, vol.286
, pp. 12524-12532
-
-
Sato, Y.1
Endo, H.2
Okuyama, H.3
-
32
-
-
55649105963
-
Clinical risk factors, DNA variants, and the development of type 2 diabetes
-
Lyssenko V, Jonsson A, Almgren P et al (2008) Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 359: 2220-2232
-
(2008)
N Engl J Med
, vol.359
, pp. 2220-2232
-
-
Lyssenko, V.1
Jonsson, A.2
Almgren, P.3
-
33
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL et al (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316: 1341-1345
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
-
34
-
-
2342633204
-
Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes
-
Gloyn AL, Pearson ER, Antcliff JF et al (2004) Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes. N Engl J Med 350: 1838-1849
-
(2004)
N Engl J Med
, vol.350
, pp. 1838-1849
-
-
Gloyn, A.L.1
Pearson, E.R.2
Antcliff, J.F.3
-
35
-
-
66449119411
-
Glutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion
-
Reinbothe TM, Ivarsson R, Li DQ et al (2009) Glutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion. Mol Endocrinol 23: 893-900
-
(2009)
Mol Endocrinol
, vol.23
, pp. 893-900
-
-
Reinbothe, T.M.1
Ivarsson, R.2
Li, D.Q.3
-
36
-
-
0037434991
-
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40
-
Itoh Y, Kawamata Y, Harada M et al (2003) Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 422: 173-176
-
(2003)
Nature
, vol.422
, pp. 173-176
-
-
Itoh, Y.1
Kawamata, Y.2
Harada, M.3
-
37
-
-
65549114432
-
Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice
-
Nagasumi K, Esaki R, Iwachidow K et al (2009) Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice. Diabetes 58: 1067-1076
-
(2009)
Diabetes
, vol.58
, pp. 1067-1076
-
-
Nagasumi, K.1
Esaki, R.2
Iwachidow, K.3
-
38
-
-
70350561694
-
Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets
-
Alquier T, Peyot ML, Latour MG et al (2009) Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. Diabetes 58: 2607-2615
-
(2009)
Diabetes
, vol.58
, pp. 2607-2615
-
-
Alquier, T.1
Peyot, M.L.2
Latour, M.G.3
-
39
-
-
33746507174
-
FoxA2 Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs ?8118 and ?7750 upstream from the transcription start site
-
Raum JC, Gerrish K, Artner I et al (2006) FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs ?8118 and ?7750 upstream from the transcription start site. Mol Cell Biol 26: 5735-5743
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5735-5743
-
-
Raum, J.C.1
Gerrish, K.2
Artner, I.3
-
41
-
-
20344368579
-
MafA is a key regulator of glucose-stimulated insulin secretion
-
Zhang C, Moriguchi T, Kajihara M et al (2005) MafA is a key regulator of glucose-stimulated insulin secretion. Mol Cell Biol 25: 4969-4976
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4969-4976
-
-
Zhang, C.1
Moriguchi, T.2
Kajihara, M.3
-
42
-
-
79953756654
-
Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells
-
Aguayo-Mazzucato C, Koh A, El Khattabi I et al (2011) Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells. Diabetologia 54: 583-593
-
(2011)
Diabetologia
, vol.54
, pp. 583-593
-
-
Aguayo-Mazzucato, C.1
Koh, A.2
El Khattabi, I.3
-
43
-
-
33745197298
-
MafK overexpression in pancreatic beta-cells caused impairment of glucose-stimulated insulin secretion
-
Shimohata H, Yoh K, Morito N, Shimano H, Kudo T, Takahashi S (2006) MafK overexpression in pancreatic beta-cells caused impairment of glucose-stimulated insulin secretion. Biochem Biophys Res Commun 346: 671-680
-
(2006)
Biochem Biophys Res Commun
, vol.346
, pp. 671-680
-
-
Shimohata, H.1
Yoh, K.2
Morito, N.3
Shimano, H.4
Kudo, T.5
Takahashi, S.6
-
44
-
-
77957583357
-
MafA and MafB regulate genes critical to beta-cells in a unique temporal manner
-
Artner I, Hang Y, Mazur M et al (2010) MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes 59: 2530-2539
-
(2010)
Diabetes
, vol.59
, pp. 2530-2539
-
-
Artner, I.1
Hang, Y.2
Mazur, M.3
-
45
-
-
21044433282
-
The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells
-
Schisler JC, Jensen PB, Taylor DG et al (2005) The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells. Proc Natl Acad Sci U S A 102: 7297-7302
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7297-7302
-
-
Schisler, J.C.1
Jensen, P.B.2
Taylor, D.G.3
-
47
-
-
0027479441
-
Glucose sensing in pancreatic islet beta cells: The key role of glucokinase and the glycolytic intermediates
-
German MS (1993) Glucose sensing in pancreatic islet beta cells: the key role of glucokinase and the glycolytic intermediates. Proc Natl Acad Sci U S A 90: 1781-1785
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1781-1785
-
-
German, M.S.1
-
48
-
-
0027203345
-
Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport
-
Heimberg H, de Vos A, Vandercammen A, van Schaftingen E, Pipeleers D, Schuit F (1993) Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport. EMBO J 12: 2873-2879
-
(1993)
EMBO J
, vol.12
, pp. 2873-2879
-
-
Heimberg, H.1
De Vos, A.2
Vandercammen, A.3
Van Schaftingen, E.4
Pipeleers, D.5
Schuit, F.6
-
49
-
-
34147163066
-
EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets
-
Konstantinova I, Nikolova G, Ohara-Imaizumi M et al (2007) EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. Cell 129: 359-370
-
(2007)
Cell
, vol.129
, pp. 359-370
-
-
Konstantinova, I.1
Nikolova, G.2
Ohara-Imaizumi, M.3
-
50
-
-
17644392453
-
Heterogeneity in distribution of amyloid-positive islets in type-2 diabetic patients
-
Borromeo CM, Pottier X, In't Veld PA et al (2005) Heterogeneity in distribution of amyloid-positive islets in type-2 diabetic patients. Virchows Arch 446: 232-238
-
(2005)
Virchows Arch
, vol.446
, pp. 232-238
-
-
Borromeo, C.M.1
Pottier, X.2
In't Veld, P.A.3
|