Cyclosporine treatment improves mesenteric perfusion and attenuates necrotizing enterocolitis (NEC)-like intestinal injury in asphyxiated newborn piglets during reoxygenation

Intensive Care Medicine

Volumn 38, Issue 3, 2012, Pages 482-490

  Gill, Richdeep S ^a   Manouchehri, Namdar ^a   Lee, Tze Fun ^a   Cho, Woo Jung ^b   Thiesen, Aducio ^a   Churchill, Thomas ^a   Bigam, David L ^a   Cheung, Po Yin ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

Asphyxia; Cyclosporine; Necrotizing enterocolitis; Piglets; Reoxygenation

Indexed keywords

CYCLOSPORIN A; LACTIC ACID; OXYGEN; SODIUM CHLORIDE;

ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; CARDIOGENIC SHOCK; CONTROLLED STUDY; DRUG EFFICACY; HEART MUSCLE INJURY; HEART OUTPUT; HEART PERFUSION; HEMODYNAMIC MONITORING; HISTOPATHOLOGY; HYPOTENSION; INTESTINE; INTESTINE INJURY; LACTATE BLOOD LEVEL; LACTIC ACIDOSIS; LUNG ALVEOLUS; MEAN ARTERIAL PRESSURE; MESENTERY BLOOD FLOW; NECROTIZING ENTEROCOLITIS; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; OXYGEN SUPPLY; OXYGEN THERAPY; PH; PIGLET; PNEUMATOSIS INTESTINALIS; REOXYGENATION; SHAM PROCEDURE; SUPERIOR MESENTERIC ARTERY; SUPERIOR MESENTERIC ARTERY PERFUSION;

ALBERTA; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANOXIA; ASPHYXIA; CYCLOSPORINE; ENTEROCOLITIS, NECROTIZING; HEMODYNAMICS; IMMUNOSUPPRESSIVE AGENTS; INTESTINES; MESENTERIC ARTERIES; OXIDATIVE STRESS; RANDOM ALLOCATION; REPERFUSION INJURY; RESUSCITATION; SWINE;

EID: 84862530521     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-011-2436-5     Document Type: Article

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