Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation

Pediatric Research

Volumn 62, Issue 5, 2007, Pages 559-563

  Solberg, Rønnaug ^a   Andresen, Jannicke H ^a   Escrig, Raquel ^b   Vento, Maximo ^b   Saugstad, Ola Didrik ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b HOSPITAL INFANTIL LA FE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 HYDROXYPHENYL)ALANINE; 8 HYDROXYDEOXYGUANOSINE; AMINO ACID; DNA; HYDROXYL GROUP; OXYGEN; PHENYLALANINE; 2 TYROSINE; 2-TYROSINE; 8 OXO 7 HYDRODEOXYGUANOSINE; 8-OXO-7-HYDRODEOXYGUANOSINE; BIOLOGICAL MARKER; DEOXYGUANOSINE; DRUG DERIVATIVE; REACTIVE OXYGEN METABOLITE; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOXEMIA; INSPIRATORY CAPACITY; MALE; NEWBORN; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RESUSCITATION; TANDEM MASS SPECTROMETRY; URINALYSIS; ANIMAL; ANOXIA; ARTIFICIAL VENTILATION; DISEASE MODEL; DRUG EFFECT; METABOLISM; OXYGEN THERAPY; SWINE; TIME; URINE;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DISEASE MODELS, ANIMAL; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; OXIDATIVE STRESS; OXYGEN; OXYGEN INHALATION THERAPY; PHENYLALANINE; REACTIVE OXYGEN SPECIES; RESPIRATION, ARTIFICIAL; SWINE; TANDEM MASS SPECTROMETRY; TIME FACTORS; TYROSINE;

EID: 38849191937     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e318156e8aa     Document Type: Article

References (28)

1. International Liaison Committee on Resuscitation 2005 2005 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. Part 7: Neonatal resuscitation. Resuscitation 67:293-303
2. Kondo M, Itoh S, Isobe K, Kondo M, Kunikata T, Imai T, Onishi S 2000 Chemiluminescence because of the production of reactive oxygen species in the lungs of newborn piglets during resuscitation periods after asphyxiation load. Pediatr Res 47:524-527
3. Saugstad OD, Ramji S, Vento M 2005 Resuscitation of depressed newborn infants with ambient air or pure oxygen: a meta-analysis. Biol Neonate 87:27-34
4. Vento M, Sastre J, Asensi MA, Vina J 2005 Room-air resuscitation causes less damage to heart and kidney than 100% oxygen. Am J Respir Crit Care Med 172:1393-1398
5. Naumburg E, Bellocco R, Cnattingius S, Jonzon A, Ekbom A 2002 Supplementary oxygen and risk of childhood lymphatic leukaemia. Acta Paediatr 91:1328-1333
6. Spector LG, Klebanoff MA, Feusner JH, Georgieff MK, Ross JA 2005 Childhood cancer following neonatal oxygen supplementation. J Pediatr 147:27-31
7. Shigenaga MK, Gimeno CJ, Ames BN 1989 Urinary 8-hydroxy-2′- deoxyguanosine as a biological marker of in vivo oxidative DNA damage. Proc Natl Acad Sci USA 86:9697-9701
8. Wu LL, Chiou CC, Chang PY, Wu JT 2004 Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics. Clin Chim Acta 339:1-9
9. Lubec G, Widness JA, Hayde M, Menzel D, Pollak A 1997 Hydroxyl radical generation in oxygen-treated infants. Pediatrics 100:700-704
10. Munkeby BH, Borke WB, Bjornland K, Sikkeland LI, Borge GI, Halvorsen B, Saugstad OD 2004 Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets. Pediatr Res 56:783-790
11. Cooke MS, Olinski R, Evans MD 2006 Does measurement of oxidative damage to DNA have clinical significance? Clin Chim Acta 365:30-49
12. Evans MD, Dizdaroglu M, Cooke MS 2004 Oxidative DNA damage and disease: induction, repair and significance. Mutat Res 567:1-61
13. Biondi R, Ambrosio G, Liebgott T, Cardounel AJ, Bettini M, Tritto I, Zweier JL 2006 Hydroxylation of D-phenylalanine as a novel approach to detect hydroxyl radicals: application to cardiac pathophysiology. Cardiovasc Res 71:322-330
14. de Zwart LL, Meerman JH, Commandeur JN, Vermeulen NP 1999 Biomarkers of free radical damage applications in experimental animals and in humans. Free Radic Biol Med 26:202-226
15. Cooke MS, Evans MD, Dove R, Rozalski R, Gackowski D, Siomek A, Lunec J, Olinski R 2005 DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine. Mutat Res 574:58-66
16. Olinski R, Rozalski R, Gackowski D, Foksinski M, Siomek A, Cooke MS 2006 Urinary measurement of 8-OxodG, 8-OxoGua, and 5HMUra: a noninvasive assessment of oxidative damage to DNA. Antioxid Redox Signal 8:1011-1019
17. Orhan H, Vermeulen NP, Tump C, Zappey H, Meerman JH 2004 Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography-tandem mass spectrometry as non-invasive biomarkers for oxidative damage. J Chromatogr B Analyt Technol Biomed Life Sci 799:245-254
18. Cooke MS, Lunec J, Evans MD 2002 Progress in the analysis of urinary oxidative DNA damage. Free Radic Biol Med 33:1601-1614
19. Renner T, Fechner T, Scherer G 2000 Fast quantification of the urinary marker of oxidative stress 8-hydroxy-2′-deoxyguanosine using solid-phase extraction and high-performance liquid chromatography with triple-stage quadrupole mass detection. J Chromatogr B Biomed Sci Appl 738:311-317
20. Tsukahara H, Jiang MZ, Ohta N, Sato S, Tamura S, Hiraoka M, Maeda M, Mayumi M 2004 Oxidative stress in neonates: evaluation using specific biomarkers. Life Sci 75:933-938
21. Tsukahara H, Toyo-Oka M, Kanaya Y, Ogura K, Kawatani M, Hata A, Hiraoka M, Mayumi M 2005 Quantitation of glutathione S transferase-pi in the urine of preterm neonates. Pediatr Int 47:528-531
22. Loft S, Svoboda P, Kasai H, Tjonneland A, Vogel U, Moller P, Overvad K, Raaschou-Nielsen O 2006 Prospective study of 8-oxo-7,8-dihydro-2′- deoxyguanosine excretion and the risk of lung cancer. Carcinogenesis 27:1245-1250
23. Greenberg JA, Wei H, Ward K, Boozer CN 2000 Whole-body metabolic rate appears to determine the rate of DNA oxidative damage and glycation involved in aging. Mech Ageing Dev 115:107-117
24. Dizdaroglu M, Jaruga P, Birincioglu M, Rodriguez H 2002 Free radical-induced damage to DNA: mechanisms and measurement. Free Radic Biol Med 32:1102-1115
25. Vento M, Asensi M, Sastre J, Garcia-Sala F, Pallardo FV, Vina J 2001 Resuscitation with room air instead of 100% oxygen prevents oxidative stress in moderately asphyxiated term neonates. Pediatrics 107:642-647
26. Mansell AL, McAteer AL, Pipkin AC 1992 Maturation of interdependence between extra-alveolar arteries and lung parenchyma in piglets. Circ Res 71:701-710
27. Standaert TA, Wilham BE, Mayock DE, Watchko JF, Gibson RL, Woodrum DE 1991 Respiratory mechanics of the piglet during the first month of life. Pediatr Pulmonol 11:294-301
28. Pond WG, Boleman SL, Fiorotto ML, Ho H, Knabe DA, Mersmann HJ, Savell JW, Su DR 2000 Perinatal ontogeny of brain growth in the domestic pig. Proc Soc Exp Biol Med 223:102-108