Hybrid magnetic hydrogel: A potential system for controlled drug delivery by means of alternating magnetic fields

Polymers

Volumn 4, Issue 2, 2012, Pages 1157-1169

  Giani, Gabriele ^a   Fedi, Serena ^a   Barbucci, Rolando ^a  

^a Centro Interuniversitario Sistemi Medici Avanzati (CRISMA)   (Italy)

Author keywords

AFM analysis; Functionalization of nanoparticles; Magnetic hydrogel; Magnetic nanoparticles; Voltammetry analysis of nanoparticles

Indexed keywords

AFM; ALTERNATING MAGNETIC FIELD; BIOMEDICAL SCIENCE; CARBOXYMETHYLCELLULOSE; CONTROLLED DRUG RELEASE; CROSSLINKER; ELECTROCHEMICAL ANALYSIS; FUNCTIONALIZATIONS; FUNCTIONALIZED; HYBRID HYDROGELS; INNOVATIVE MATERIALS; MAGNETIC NANOPARTICLES; MAGNETIC STIMULI; POTENTIAL SYSTEMS; TRIMETHOXYSILANE;

CONTROLLED DRUG DELIVERY; CROSSLINKING; HYBRID MATERIALS; INFRARED SPECTROSCOPY; INNOVATION; MAGNETIC FIELDS; NANOMAGNETICS; NANOPARTICLES;

HYDROGELS;

EID: 84862519038     PISSN: None     EISSN: 20734360     Source Type: Journal    
DOI: 10.3390/polym4021157     Document Type: Article

References (33)

1. Barbucci, R.; Giardino, R.; de Cagna, M.; Golini, L; Pasqui, D. Inter-Penetrating Hydrogels (IPHs) as a new class of injectable polysaccharide hydrogels with thixotropic nature and interesting mechanical and biological properties. Soft Matter 2010, 6, 3524-3532.
2. Peppas, N.A. Hydrogels in Medicine and Pharmacy; CRC Press: Boca Raton, FL, USA, 1987.
3. Schexnailder, P.J.; Schmidt, G. Nanocomposite hydrogels. Colloid Polym. Sci. 2009, 287, 1-11.
4. Narayana Reddy, N.; Varaprasad, K.; Subba Reddy, G.V.; Reddy, K.M.S.; Mohan Reddy, K.M.; Mohana Raju, K. Evaluation of blood compatibility and drug release studies of gelatin based magnetic hydrogel nanocomposites. Colloids Surf. A physicochem. Eng. Asp. 2011, 385, 20-27.
5. Kim, J.; Chun, C.; Kimd, B.; Hong, J.; Cho, J.K. Thermosensitive/magnetic poly(organophosphazene) hydrogel as a long-term magnetic resonance contrast platform. Biomaterials 2012, 33, 218-222.
6. Meenach, A.; Hilt, Z.; Anderson, W. Poly(ethylene glycol)-based magnetic hydrogel nanocomposites for hyperthermia cancer therapy. Acta Biomater. 2010, 6, 1039-1046.
7. Gaihre, B.; Khil, S.; Lee, R.; Kim, Y. Gelatin-coated magnetic iron oxide nanoparticles as carrier system: Drug loading and in vitro drug release study. Int. J. Pharm. 2009, 365, 180-189.
8. Drbohlavova, J.; Chomoucka, J.; Huska, D.; Adam, V.; Kizek, R.; Hubalek, J. Magnetic nanoparticles and targeted drug delivering. Pharmacol. Res. 2010, 62, 144-149.
9. Mahmoudi, M.; Simchi, A.; Hafeli, O.U. Superparamagnetic iron oxide nanoparticles with rigid cross-linked polyethylene glycol fumarate coating for application in imaging and drug delivery. J. Phys. Chem. C 2009, 113, 8124-8131.
10. Satarkar S.; Hilt, Z. Hydrogel nanocomposites as remote-controlled biomaterials. Acta Biomater. 2008, 4, 11-16.
11. Satarkar, S.; Hilt, Z. Magnetic hydrogel nanocomposites for remote controlled pulsatile drug release. J. Control. Release 2008, 130, 246-251.
12. Barbucci, R.; Pasqui, D.; Giani, G.; de Cagna, M.; Fini, M.; Giardino, R.; Atrei, A. A novel strategy for engineering hydrogels with ferromagnetic nanoparticles as crosslinkers of the polymer chains. Potential applications as a targeted drug delivery system. Soft Matter 2011, 7, 5558-5565.
13. Hu, S.H.; Liu, T.Y.; Liu, D.M.; Chen, Y. Controlled pulsatile drug release from a ferrogelby a high-frequency magnetic field. Macromolecules 2007, 40, 6786-6788.
14. Brulé, S.; Levy, M.; Wilhelm, C.; Letourneur, D.; Gazeau, F.; Ménager, C.; Le Visage, C. Doxorubicin release triggered by alginate embedded magnetic nanoheaters: A combined therapy. Adv. Mater. 2011, 23, 787-790.
15. Liang, Y., Zhang, L.M.; Jiang, W.; Lei, W. Embedding magnetic nanoparticles into polysaccharide-based hydrogels for magnetically assisted bioseparation. Chem. Phys. Chem. 2007, 8, 2367-2372.
16. Liu, H.; Wang, C.; Gao, Q.; Chen, J.; Ren, B.; Liu, X.; Tong, Z. Facile fabrication of well-defined hydrogel beads with magnetic nanocomposite shells. Int. J. Pharm. 2009, 376, 92-98.
17. Pasqui, D.; Atrei, A.; Giani, G.; de Cagna, M.; Barbucci, R.; Metal oxide nanoparticles as cross-linkers in polymeric hybrid hydrogels. Mater. Lett. 2011, 65, 392-395.
18. Shin, K.; Cho,Y.; Choi, J.; Kim, K. Facile synthesis of silver-deposited silanized magnetite nanoparticles and their application for catalytic reduction of nitrophenols. Appl. Catal. A Gen. 2012. In press.
19. Berghoute, Y.; Mendonc, M.H.; Hamdani, M.; Pereira, M.I.S. Electrochemical behaviour of FexCo3-xO4 with (x = 0, 1, 2 and 3) oxides thin film electrodes in alkaline medium. J. Appl. Electrochem. 2009, 39, 2469-2479.
20. Laouini, E.; Douch, J.; Hamdani, M.; Berghoute, Y.; Mendonc, M.H.; Pereira, M.I.S.; Singht, R.N. Cathodic behaviour of CoFe2O4 spinel electrodes in alkaline medium. J. Appl. Electrochem. 2011, 41, 731-740.
21. Choi, Y.J.; Tzy-Jiun, U.; Luo, M. Sol-gel chemistry of an aqueous precursor solution for YBCO thin films. J. Sol-Gel. Sci. Technol. 2009, 51,124-133.
22. Hernando J.; Pourrostami, T.; Garrido, J.A.; Williams, O.A.; Gruen, D.M.; Kromka, A.; Steinmüller, D.; Stutzmann, M. Immobilization of horseradish peroxidase via an amino silane on oxidized ultrananocrystalline diamond. Diamond Relat. Mater. 2007, 16, 138-143.
23. Wang, M.; Liechti, K.M.; Wang, Q.; White, J.M. Self-assembled silane monolayers: Fabrication with nanoscale uniformity. Langmuir 2005, 21, 1848-1857.
24. Moon, J.H.; Shin, J.W.; Kim, S.Y.; J. W. Park formation of uniform aminosilane thin layers: An imine formation to measure relative surface density of the amine group. Langmuir 1996, 12, 4621-4624.
25. Pallandre, A.; Glinel, K.; Jonas, A.M.; Nysten, B. Binary nanopatterned surfaces prepared from siane monolayers. Nanoletters 2004, 4, 365-371.
26. Kurth, D.G.; Bein, T. Surface reactions on thin layers of silane coupling agents. Langmuir 1993, 9, 2965-2973.
27. Xu, R. Progress in nanoparticles characterization: Sizing and zeta potential measurement. Particuology 2008, 6, 112-115.
28. Rodríguez-Arco, L.; López-López, M.; González-Caballero, F.; Durán, J. Steric repulsion as a way to achieve the required stability for the preparation of ionic liquid-based ferrofluids. J. Colloid Interf. Sci. 2011, 357, 252-254.
29. Bihari, P.; Vippola, M.; Schultes, S.; Praetner, M.; Khandoga, A.; Reichel, C.; Coester, C.; Tuomi, T.; Rehbergand, M.; Krombach, F. Optimized dispersion of nanoparticles for biological in vitro and in vivo studies. Part. Fibre Toxicol. 2008, 5, doi:10.1186/1743-8977-5-14. Avaliable online: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584664/ (accessed on 28 April 2012).
30. Zhang, X.; Yin, L.; Tang, M.; Pu, Y. Optimized method for preparation of TiO2 nanoparticles dispersion for biological study. J. Nanosci. Nanotechnol. 2010, 10, 5213-5219.
31. Vargas, A.F.; Orozco, V.H.; Rault, F.; Giraud, S.; Devaux, E.; Lopez B. L. Influence of fiber-like nanofillers on the rheological, mechanical, thermal and fire properties of polypropylene: An application to multifilament yarn. Compos. Part. A Appl. Sci. Manuf. 2010, 41, 1797-1806.
32. Tjong, S.C. Structural and mechanical properties of polymer nanocomposites. Mater. Sci. Eng. Rep. 2006, 53, 73-197.
33. Hu, X.; Zhou, J.; Zhang, N.; Tan, H.; Gao, C. Preparation and properties of an injectable scaffold of poly(lactic-co-glycolic acid) microparticles/chitosan hydrogel. J. Mech. Behav. 2008, 1, 352-359.