Glycosyl phosphatidylinositol-anchored ceruloplasmin is expressed by rat sertoli cells and is concentrated in detergent-insoluble membrane fractions

Biology of Reproduction

Volumn 61, Issue 4, 1999, Pages 1042-1049

  Fortna, Ryan R ^a   Watson, Hadiya A ^a   Nyquist, Sally E ^a  

^a BUCKNELL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERULOPLASMIN; DETERGENT; GLYCOSYLPHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; BIOTINYLATION; CELL CULTURE; CONTROLLED STUDY; IRON TRANSPORT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SERTOLI CELL;

ANIMALS; BLOTTING, WESTERN; CELL ADHESION; CELLS, CULTURED; CERULOPLASMIN; DETERGENTS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOSYLPHOSPHATIDYLINOSITOLS; MALE; PHOSPHOLIPASE C; RATS; RATS, SPRAGUE-DAWLEY; SERTOLI CELLS; SOLUBILITY;

EID: 0032881432     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod61.4.1042     Document Type: Article

References (52)

1. Low MG, Zilversmit DB. Role of phosphatidylinositol in attachment of alkaline phosphatase to membranes. Biochemistry 1980; 19:3913-3918.
2. Nosjean O, Brolay A, Roux B. Mammalian GPI proteins: sorting, membrane residence and functions. Biochim Biophys Acta 1997; 1331:153-186.
3. Englund PT. The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors. Annu Rev Biochem 1993; 62:121-138.
4. Hannan LA, Lisanti MP, Rodrigues-Boulan E, Edidin M. Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells. J Cell Biol 1993; 120:353-358.
5. Ali S, Hall J, Hazlewood GP, Hirst BH, Gilbert HJ. A protein targeting signal that functions in polarized epithelial cells in vivo. Biochem J 1996; 315:857-862.
6. Mostov KE, Cardone MH. Regulation of protein traffic in polarized epithelial cells. Bioessays 1995; 17:129-138.
7. Brown DA, Rose JK. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell 1992; 68:533-544.
8. Simons K, Ikonen E. Functional rafts in cell membranes. Nature 1997; 387:569-572.
9. Anderson RGW. The caveolae membrane system. Annu Rev Biochem 1998; 67:199-225.
10. Parton RG, Simons K. Digging into caveolae. Science 1995; 269: 1398-1399.
11. Lisanti MP, Tang Z, Scherer PE, Sargiacomo M. Caveolae purification and glycosylphosphatidylinositol-linked protein sorting in polarized epithelia. Methods Enzymol 1995; 250:655-668.
12. Schnitzer JE, McIntosh DP, Dvorak AM, Liu J, Oh P. Separation of caveolae from associated microdomains of GPI-anchored proteins. Science 1995; 269:1435-1439.
13. Harder T, Simons K. Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains. Curr Opin Cell Biol 1997; 9:534-542.
14. Parton RG. Caveolae and caveolins. Curr Opin Cell Biol 1996; 8: 542-548.
15. Gorodinsky A, Harris DA. Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin. J Cell Biol 1995; 129:619-627.
16. Fra AM, Williamson E, Simons K. Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae. J Biol Chem 1994; 269:30745-30748.
17. Lisanti MP, Scherer PE, Tang Z, Sargiacomo M. Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis. Trends Cell Biol 1994; 4:231-235.
18. Anderson RGW, Kamen BA, Rothberg KG, Lacey SW. Potocytosis: sequestration and transport of small molecules by caveolae. Science 1992; 255:410-411.
19. Nagano T, Suzuki F. Cell to cell relationships in the seminiferous epithelium in the mouse embryo. Cell Tissue Res 1978; 189:389-401.
20. Morales C, Clermont Y. Receptor-mediated endocytosis of transferrin by Sertoli cells of the rat. Biol Reprod 1986; 35:393-405.
21. Kaplan J, O'Halloran TV. Iron metabolism in eukaryotes: Mars and Venus at it again. Science 1996; 271:1510-1512.
22. Harris ZL, Takahashi Y, Miyajima H, Serizawa M, MacGillivray RTA, Gitlin JD. Aceruloplasminemia: molecular characterization of this disorder of iron metabolism. Proc Natl Acad Sci USA 1995; 92:2539-2543.
23. Okamoto N, Wada S, Oga T, Kawabata Y, Baba Y, Habu D, Takeda Z, Wada Y. Hereditary ceruloplasmin deficiency with hemosiderosis. Hum Genet 1996; 97:755-758.
24. Harris ZL, Klomp LWJ, Gitlin JD. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Am J Clin Nutr 1998; 67(suppl):972S-977S.
25. Mukhopadhyay CK, Attieh ZK, Fox PL. Role of ceruloplasmin in cellular iron uptake. Science 1998; 279:714-717.
26. Attieh ZK, Mukhopadyay CK, Seshadri V, Tripoulas NA, Fox PL. Ceruloplasmin ferroxidase activity stimulates cellular iron uptake by a trivalent cation-specific transport mechanism. J Biol Chem 1999; 274:1116-1123.
27. de Silva D, Askwith C, Eide DJ, Kaplan J. The FET3 gene product required for high affinity iron transport in yeast is a cell surface ferroxidase. J Biol Chem 1995; 270:1098-1101.
28. de Silva D, Davis-Kaplan S, Fergestad J, Kaplan J. Purification and characterization of Fet3 protein, a yeast homologue of ceruloplasmin. J Biol Chem 1997; 272:14208-14213.
29. Stearman R, Yuan DS, Yamaguchi-Iwai Y, Klausner RD, Dancis A. A permease-oxidase complex involved in high-affinity iron uptake in yeast. Science 1996; 271:1552-1557.
30. Askwith C, Eide D, Van Ho A, Bernard PS, Li L, Davis-Kaplan S, Sipe DM, Kaplan J. The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake. Cell 1994; 76:403-410.
31. Yuan DS, Stearman R, Dancis A, Dunn T, Beeler T. The Menkes/ Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake. Proc Natl Acad Sci USA 1995; 92:2632-2636.
32. Skinner MK, Griswold MD. Sertoli cells synthesize and secrete transferrin-like protein. J Biol Chem 1980; 255:9523-9525.
33. Skinner MK, Griswold MD. Sertoli cells synthesize and secrete a ceruloplasmin-like protein. Biol Reprod 1983; 28:1225-1229.
34. Griswold MD. Protein secretions of Sertoli cells. Int Rev Cytol 1988; 110:133-156.
35. Sylvester SR, Griswold MD. Molecular biology of iron transport in the testis. In: de Kretser D (ed.), Molecular Biology of the Male Reproductive System. New York: Academic Press; 1993: 311-326.
36. Page KC, Killian GJ, Nyquist SE. Sertoli cell glycosylation patterns as affected by culture age and extracellular matrix. Biol Reprod 1990; 43:659-664.
37. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193:265-275.
38. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T. Nature 1970; 227:680-685.
39. Sargiacomo M, Sudol M, Tang Z, Lisanti MP. Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells. J Cell Biol 1993; 122: 789-807.
40. Doering TL, Englund PT, Hart GW. Detection of glycolipid anchors on proteins. Curr Prot Mol Biol 1993; (suppl 22):17.8.1-17.8.13.
41. Byers SW, Hadley MA, Djakiew D. Growth and characterization of polarized monolayers of epithelial cells and Sertoli cells in dual environment culture chambers. J Androl 1986; 7:59-68.
42. Janecki A, Steinberger A. Polarized Sertoli cell functions in a new two-compartment culture system. J Androl 1986; 7:69-71.
43. Lisanti MP, Sargiacomo M, Graeve L, Saltiel AR, Rodriguez-Boulan E. Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line. Proc Natl Acad Sci USA 1988; 85:9557-9561.
44. Salzer JL, Lovejoy L, Linder MC, Rosen C. Ran-2, a glial lineage marker, is a GPI-anchored form of ceruloplasmin. J Neurosci Res 1998; 54:147-157.
45. Sato M, Gitlin JD. Mechanisms of copper incorporation during the biosynthesis of human ceruloplasmin. J Biol Chem 1991; 266:5128-5134.
46. 59Fe across confluent epithelial sheets of Sertoli cells grown in bicameral cell culture chambers. J Androl 1986; 7: 355-366.
47. Wright WW, Parvinen M, Musto NA, Gunslua GL, Phillips DM, Mather JP, Bardin CW. Identification of stage-specific proteins synthesized by rat seminiferous tubules. Biol Reprod 1983; 29:257-270.
48. Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, Nussberger S, Gollan JL, Hediger MA. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997; 388:482-488.
49. Andrews NC, Levy JE. Iron is hot: an update on the pathophysiology of hemochromatosis. Blood 1998; 92:1845-1851.
50. Low MG. Glycosyl-phosphatidylinositol: a versatile anchor for cell surface proteins. FASEB J 1989; 3:1600-1608.
51. Fritz BA, Lowe AW. Polarized GP2 secretion in MDCK cells via GP1 targeting and apical membrane-restricted proteolysis. Am J Physiol 1996; 270:G176-G183.
52. Patel BN, David S. A novel glycosylphosphatidylinositol-anchored form of ceruloplasmin is expressed by mammalian astrocytes. J Biol Chem 1997; 272:20185-20190.