-
1
-
-
33845784758
-
Blood-brain barrier delivery
-
Pardridge, W. M. Blood-brain barrier delivery. Drug Discov. Today, 2007, 12(1/2), 54-61.
-
(2007)
Drug Discov. Today
, vol.12
, Issue.1-2
, pp. 54-61
-
-
Pardridge, W.M.1
-
2
-
-
60749087739
-
Assays to predict drug permeation across the blood-brain barrier, and distribution to brain
-
Abbott, N. J.; Dolman, D. E.; Patabendige, A. K. Assays to predict drug permeation across the blood-brain barrier, and distribution to brain. Curr. Drug Metab., 2008, 9, (9), 901-910.
-
(2008)
Curr. Drug Metab
, vol.9
, Issue.9
, pp. 901-910
-
-
Abbott, N.J.1
Dolman, D.E.2
Patabendige, A.K.3
-
3
-
-
0037559607
-
The blood-brain barrier choline transporter as a brain drug delivery vector
-
Allen, D. D.; Lockman, P. R. The blood-brain barrier choline transporter as a brain drug delivery vector. Life Sci., 2003, 73(13), 1609-1615.
-
(2003)
Life Sci
, vol.73
, Issue.13
, pp. 1609-1615
-
-
Allen, D.D.1
Lockman, P.R.2
-
4
-
-
37249088037
-
Chemical modification and formulation approaches to elevated drug transport across cell membranes
-
Majumdar, S.; Mitra, A. K. Chemical modification and formulation approaches to elevated drug transport across cell membranes. Expert Opin. Drug Deliv., 2006, 3(4), 511-527.
-
(2006)
Expert Opin. Drug Deliv
, vol.3
, Issue.4
, pp. 511-527
-
-
Majumdar, S.1
Mitra, A.K.2
-
5
-
-
77649216536
-
Membrane transporters in drug development
-
Giacomini, K. M.; Huang, S. M.; Tweedie, D. J.; Benet, L. Z.; Brouwer, K. L.; Chu, X.; Dahlin, A.; Evers, R.; Fischer, V.; Hillgren, K. M.; Hoffmaster, K. A.; Ishikawa, T.; Keppler, D.; Kim, R. B.; Lee, C. A.; Niemi, M.; Polli, J. W.; Sugiyama, Y.; Swaan, P. W.; Ware, J. A.; Wright, S. H.; Yee, S. W.; Zamek- Gliszczynski, M. J.; Zhang, L. Membrane transporters in drug development. Nat. Rev. Drug Discov., 2010, 9(3), 215-236.
-
(2010)
Nat. Rev. Drug Discov
, vol.9
, Issue.3
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
Chu, X.6
Dahlin, A.7
Evers, R.8
Fischer, V.9
Hillgren, K.M.10
Hoffmaster, K.A.11
Ishikawa, T.12
Keppler, D.13
Kim, R.B.14
Lee, C.A.15
Niemi, M.16
Polli, J.W.17
Sugiyama, Y.18
Swaan, P.W.19
Ware, J.A.20
Wright, S.H.21
Yee, S.W.22
Zamek-Gliszczynski, M.J.23
Zhang, L.24
more..
-
6
-
-
77649216536
-
Membrane transporters in drug development
-
Giacomini, K. M.; Huang, S. M.; Tweedie, D. J.; Benet, L. Z.; Brouwer, K. L.; Chu, X.; Dahlin, A.; Evers, R.; Fischer, V.; Hillgren, K. M.; Hoffmaster, K. A.; Ishikawa, T.; Keppler, D.; Kim, R. B.; Lee, C. A.; Niemi, M.; Polli, J. W.; Sugiyama, Y.; Swaan, P. W.; Ware, J. A.; Wright, S. H.; Yee, S. W.; Zamek- Gliszczynski, M. J.; Zhang, L. Membrane transporters in drug development. Nat. Rev. Drug Discov., 2010, 9(3), 215-236.
-
(2010)
Nat. Rev. Drug Discov
, vol.9
, Issue.3
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
Chu, X.6
Dahlin, A.7
Evers, R.8
Fischer, V.9
Hillgren, K.M.10
Hoffmaster, K.A.11
Ishikawa, T.12
Keppler, D.13
Kim, R.B.14
Lee, C.A.15
Niemi, M.16
Polli, J.W.17
Sugiyama, Y.18
Swaan, P.W.19
Ware, J.A.20
Wright, S.H.21
Yee, S.W.22
Zamek-Gliszczynski, M.J.23
Zhang, L.24
more..
-
7
-
-
33745521753
-
The rat blood-brain barrier transcriptome
-
Enerson, B. E.; Drewes, L. R. The rat blood-brain barrier transcriptome. J. Cereb. Blood Flow Metab., 2006, 26(7), 959-973.
-
(2006)
J. Cereb. Blood Flow Metab
, vol.26
, Issue.7
, pp. 959-973
-
-
Enerson, B.E.1
Drewes, L.R.2
-
8
-
-
17644364388
-
Dynamics of CNS barriers: Evolution, differentiation, and modulation
-
Abbott, N. J., Dynamics of CNS barriers: evolution, differentiation, and modulation. Cell Mol. Neurobiol., 2005, 25(1), 5-23.
-
(2005)
Cell Mol. Neurobiol
, vol.25
, Issue.1
, pp. 5-23
-
-
Abbott, N.J.1
-
9
-
-
0014481056
-
Junctions between intimately apposed cell membranes in the vertebrate brain
-
Brightman, M. W.; Reese, T. S. Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell Biol., 1969, 40(3), 648-677.
-
(1969)
J. Cell Biol
, vol.40
, Issue.3
, pp. 648-677
-
-
Brightman, M.W.1
Reese, T.S.2
-
10
-
-
0025048342
-
Electrical resistance across the blood-brain barrier in anaesthetized rats: A developmental study
-
Butt, A. M.; Jones, H. C.; Abbott, N. J. Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study. J. Physiol., 1990, 429, 47-62.
-
(1990)
J. Physiol
, vol.429
, pp. 47-62
-
-
Butt, A.M.1
Jones, H.C.2
Abbott, N.J.3
-
11
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
Abbott, N. J.; Patabendige, A. A.; Dolman, D. E.; Yusof, S. R.; Begley, D. J. Structure and function of the blood-brain barrier. Neurobiol. Dis., 2010, 37(1), 13-25.
-
(2010)
Neurobiol. Dis
, vol.37
, Issue.1
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.2
Dolman, D.E.3
Yusof, S.R.4
Begley, D.J.5
-
12
-
-
25844495011
-
Medicinal chemical properties of successful central nervous system drugs
-
Pajouhesh, H.; Lenz, G. R. Medicinal chemical properties of successful central nervous system drugs. NeuroRx, 2005, 2(4), 541-553.
-
(2005)
NeuroRx
, vol.2
, Issue.4
, pp. 541-553
-
-
Pajouhesh, H.1
Lenz, G.R.2
-
14
-
-
0013117931
-
The role of drug transporters at the blood-brain barrier
-
de Boer, A. G.; van der Sandt, I. C.; Gaillard, P. J. The role of drug transporters at the blood-brain barrier. Annu. Rev. Pharmacol. Toxicol., 2003, 43, 629-656.
-
(2003)
Annu. Rev. Pharmacol. Toxicol
, vol.43
, pp. 629-656
-
-
de Boer, A.G.1
van der Sandt, I.C.2
Gaillard, P.J.3
-
15
-
-
0042899083
-
Blood-brain barrier drug targeting: The future of brain drug development
-
Pardridge, W. M. Blood-brain barrier drug targeting: the future of brain drug development. Mol. Interv., 2003, 3(2), 90-105, 51.
-
(2003)
Mol. Interv
, vol.3
, Issue.2
, pp. 90-105
-
-
Pardridge, W.M.1
-
16
-
-
33750051608
-
The blood-brain barrier and brain drug delivery
-
Koziara, J. M.; Lockman, P. R.; Allen, D. D.; Mumper, R. J. The blood-brain barrier and brain drug delivery. J. Nanosci. Nanotechnol., 2006, 6(9-10), 2712-2735.
-
(2006)
J. Nanosci. Nanotechnol
, vol.6
, Issue.9-10
, pp. 2712-2735
-
-
Koziara, J.M.1
Lockman, P.R.2
Allen, D.D.3
Mumper, R.J.4
-
17
-
-
33748665990
-
Emerging drugs for Parkinson's disease
-
Morgan, J. C.; Sethi, K. D. Emerging drugs for Parkinson's disease. Expert Opin. Emerg. Drugs, 2006, 11(3), 403-417.
-
(2006)
Expert Opin. Emerg. Drugs
, vol.11
, Issue.3
, pp. 403-417
-
-
Morgan, J.C.1
Sethi, K.D.2
-
18
-
-
0026605172
-
Melphalan penetration of the blood-brain barrier via the neutral amino acid transporter in tumor-bearing brain
-
Cornford, E. M.; Young, D.; Paxton, J. W.; Finlay, G. J.; Wilson, W. R.; Pardridge, W. M. Melphalan penetration of the blood-brain barrier via the neutral amino acid transporter in tumor-bearing brain. Cancer Res., 1992, 52(1), 138-143.
-
(1992)
Cancer Res
, vol.52
, Issue.1
, pp. 138-143
-
-
Cornford, E.M.1
Young, D.2
Paxton, J.W.3
Finlay, G.J.4
Wilson, W.R.5
Pardridge, W.M.6
-
19
-
-
0026039484
-
Affinity of antineoplastic amino acid drugs for the large neutral amino acid transporter of the blood-brain barrier
-
Takada, Y.; Greig, N. H.; Vistica, D. T.; Rapoport, S. I.; Smith, Q. R. Affinity of antineoplastic amino acid drugs for the large neutral amino acid transporter of the blood-brain barrier. Cancer Chemother. Pharmacol., 1991, 29(2), 89-94.
-
(1991)
Cancer Chemother. Pharmacol
, vol.29
, Issue.2
, pp. 89-94
-
-
Takada, Y.1
Greig, N.H.2
Vistica, D.T.3
Rapoport, S.I.4
Smith, Q.R.5
-
20
-
-
0026708467
-
Rapid high-affinity transport of a chemotherapeutic amino acid across the blood-brain barrier
-
Takada, Y.; Vistica, D. T.; Greig, N. H.; Purdon, D.; Rapoport, S. I.; Smith, Q. R. Rapid high-affinity transport of a chemotherapeutic amino acid across the blood-brain barrier. Cancer Res., 1992, 52(8), 2191-2196.
-
(1992)
Cancer Res
, vol.52
, Issue.8
, pp. 2191-2196
-
-
Takada, Y.1
Vistica, D.T.2
Greig, N.H.3
Purdon, D.4
Rapoport, S.I.5
Smith, Q.R.6
-
21
-
-
0026535433
-
Facilitated transport of the neurotoxin, beta-N-methylamino-L-alanine, across the blood-brain barrier
-
Smith, Q. R.; Nagura, H.; Takada, Y.; Duncan, M. W. Facilitated transport of the neurotoxin, beta-N-methylamino-L-alanine, across the blood-brain barrier. J. Neurochem., 1992, 58(4), 1330-13337.
-
(1992)
J. Neurochem
, vol.58
, Issue.4
, pp. 1330-13337
-
-
Smith, Q.R.1
Nagura, H.2
Takada, Y.3
Duncan, M.W.4
-
22
-
-
77954919918
-
Targeting drug transporters - combining in silico and in vitro approaches to predict in vivo
-
Bahadduri, P. M.; Polli, J. E.; Swaan, P. W.; Ekins, S. Targeting drug transporters - combining in silico and in vitro approaches to predict in vivo. Methods Mol. Biol., 2010, 637, 65-103.
-
(2010)
Methods Mol. Biol
, vol.637
, pp. 65-103
-
-
Bahadduri, P.M.1
Polli, J.E.2
Swaan, P.W.3
Ekins, S.4
-
23
-
-
53549119190
-
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1
-
Ahlin, G.; Karlsson, J.; Pedersen, J. M.; Gustavsson, L.; Larsson, R.; Matsson, P.; Norinder, U.; Bergstrom, C. A.; Artursson, P. Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J. Med. Chem., 2008, 51(19), 5932-5942.
-
(2008)
J. Med. Chem
, vol.51
, Issue.19
, pp. 5932-5942
-
-
Ahlin, G.1
Karlsson, J.2
Pedersen, J.M.3
Gustavsson, L.4
Larsson, R.5
Matsson, P.6
Norinder, U.7
Bergstrom, C.A.8
Artursson, P.9
-
24
-
-
0344838436
-
Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1
-
Bednarczyk, D.; Ekins, S.; Wikel, J. H.; Wright, S. H. Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1. Mol. Pharmacol., 2003, 63(3), 489-498.
-
(2003)
Mol. Pharmacol
, vol.63
, Issue.3
, pp. 489-498
-
-
Bednarczyk, D.1
Ekins, S.2
Wikel, J.H.3
Wright, S.H.4
-
25
-
-
15744362693
-
Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2
-
Suhre, W. M.; Ekins, S.; Chang, C.; Swaan, P. W.; Wright, S. H. Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2. Mol. Pharmacol., 2005, 67(4), 1067-1077.
-
(2005)
Mol. Pharmacol
, vol.67
, Issue.4
, pp. 1067-1077
-
-
Suhre, W.M.1
Ekins, S.2
Chang, C.3
Swaan, P.W.4
Wright, S.H.5
-
26
-
-
0035116915
-
Characterization of the blood-brain barrier choline transporter using the in situ rat brain perfusion technique
-
Allen, D. D.; Smith, Q. R. Characterization of the blood-brain barrier choline transporter using the in situ rat brain perfusion technique. J. Neurochem., 2001, 76(4), 1032-1041.
-
(2001)
J. Neurochem
, vol.76
, Issue.4
, pp. 1032-1041
-
-
Allen, D.D.1
Smith, Q.R.2
-
27
-
-
0015053820
-
Studies on the origin of choline in the brain of the rat
-
Ansell, G. B.; Spanner, S. Studies on the origin of choline in the brain of the rat. Biochem. J., 1971, 122(5), 741-750.
-
(1971)
Biochem. J
, vol.122
, Issue.5
, pp. 741-750
-
-
Ansell, G.B.1
Spanner, S.2
-
28
-
-
0036205158
-
Nanoparticle technology for drug delivery across the blood-brain barrier
-
Lockman, P. R.; Mumper, R. J.; Khan, M. A.; Allen, D. D. Nanoparticle technology for drug delivery across the blood-brain barrier. Drug Dev. Ind. Pharm., 2002, 28(1), 1-13.
-
(2002)
Drug Dev. Ind. Pharm
, vol.28
, Issue.1
, pp. 1-13
-
-
Lockman, P.R.1
Mumper, R.J.2
Khan, M.A.3
Allen, D.D.4
-
29
-
-
80053620106
-
GLUT-1 glucose transporters in the blood-brain barrier: Differential phosphorylation
-
Devraj, K.; Klinger, M. E.; Myers, R. L.; Mokashi, A.; Hawkins, R. A.; Simpson, I. A. GLUT-1 glucose transporters in the blood-brain barrier: Differential phosphorylation. J. Neurosci. Res., 2011, 89(12), 1913-1925.
-
(2011)
J. Neurosci. Res
, vol.89
, Issue.12
, pp. 1913-1925
-
-
Devraj, K.1
Klinger, M.E.2
Myers, R.L.3
Mokashi, A.4
Hawkins, R.A.5
Simpson, I.A.6
-
30
-
-
84862508057
-
The role of glucose transporter 1 (GLUT1) in the diagnosis and therapy of tumors
-
Jóźwiak, P.; Lipińska, A. The role of glucose transporter 1 (GLUT1) in the diagnosis and therapy of tumors. Postepy. Hig. Med. Dosw. (Online), 2012, 4(66), 165-174.
-
(2012)
Postepy. Hig. Med. Dosw. (Online)
, vol.4
, Issue.66
, pp. 165-174
-
-
Jóźwiak, P.1
Lipińska, A.2
-
31
-
-
0034760860
-
Inhibition of the rat blood-brain barrier choline transporter by manganese chloride
-
Lockman, P. R.; Roder, K. E.; Allen, D. D. Inhibition of the rat blood-brain barrier choline transporter by manganese chloride. J. Neurochem., 2001, 79(3), 588-594.
-
(2001)
J. Neurochem
, vol.79
, Issue.3
, pp. 588-594
-
-
Lockman, P.R.1
Roder, K.E.2
Allen, D.D.3
-
32
-
-
79954506893
-
Exploiting nutrient transporters at the blood-brain barrier to imporve brain distribution of small molecules
-
Mittapalli, R. K.; Manda, V. K.; Adkins, C. E.; Geldenhuys, W. J.; Lockman, P. R. Exploiting nutrient transporters at the blood-brain barrier to imporve brain distribution of small molecules. Ther. Deliv., 2010, 1(6), 775-784.
-
(2010)
Ther. Deliv
, vol.1
, Issue.6
, pp. 775-784
-
-
Mittapalli, R.K.1
Manda, V.K.2
Adkins, C.E.3
Geldenhuys, W.J.4
Lockman, P.R.5
-
33
-
-
22844452785
-
Donepezil, tacrine and alpha-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB)
-
Kang, Y.S.; Lee, K.E.; Lee, N.Y.; Terasaki, T. Donepezil, tacrine and alpha-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB). Arch. Pharm. Res., 2005, 28(4), 443-450.
-
(2005)
Arch. Pharm. Res
, vol.28
, Issue.4
, pp. 443-450
-
-
Kang, Y.S.1
Lee, K.E.2
Lee, N.Y.3
Terasaki, T.4
-
34
-
-
76649134799
-
Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain
-
Kim, M. H.; Maeng, H. J.; Yu, K. H.; Lee, K. R.; Tsuruo, T.; Kim, D. D.; Shim, C. K.; Chung, S. J. Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain. J. Pharm. Sci., 2010, 99(3), 1548-1566.
-
(2010)
J. Pharm. Sci
, vol.99
, Issue.3
, pp. 1548-1566
-
-
Kim, M.H.1
Maeng, H.J.2
Yu, K.H.3
Lee, K.R.4
Tsuruo, T.5
Kim, D.D.6
Shim, C.K.7
Chung, S.J.8
-
35
-
-
79955044535
-
BPiDI: A novel selective alpha6beta2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse
-
Wooters, T. E.; Smith, A. M.; Pivavarchyk, M.; Siripurapu, K. B.; McIntosh, J. M.; Zhang, Z.; Crooks, P. A.; Bardo, M. T.; Dwoskin, L. P. BPiDI: a novel selective alpha6beta2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse. Br. J. Pharmacol., 163(2), 346-357.
-
Br. J. Pharmacol
, vol.163
, Issue.2
, pp. 346-357
-
-
Wooters, T.E.1
Smith, A.M.2
Pivavarchyk, M.3
Siripurapu, K.B.4
McIntosh, J.M.5
Zhang, Z.6
Crooks, P.A.7
Bardo, M.T.8
Dwoskin, L.P.9
-
36
-
-
68349135401
-
Nicotinic receptor-based therapeutics and candidates for smoking cessation
-
Dwoskin, L. P.; Smith, A. M.; Wooters, T. E.; Zhang, Z.; Crooks, P. A.; Bardo, M. T. Nicotinic receptor-based therapeutics and candidates for smoking cessation. Biochem. Pharmacol., 2009, 78(7), 732-743.
-
(2009)
Biochem. Pharmacol
, vol.78
, Issue.7
, pp. 732-743
-
-
Dwoskin, L.P.1
Smith, A.M.2
Wooters, T.E.3
Zhang, Z.4
Crooks, P.A.5
Bardo, M.T.6
-
37
-
-
0036025236
-
The transport of choline
-
Lockman, P. R.; Allen, D. D. The transport of choline. Drug Dev. Ind. Pharm., 2002, 28(7), 749-771.
-
(2002)
Drug Dev. Ind. Pharm
, vol.28
, Issue.7
, pp. 749-771
-
-
Lockman, P.R.1
Allen, D.D.2
-
38
-
-
0037364162
-
ADMET in silico modelling: Towards prediction paradise?
-
van de Waterbeemd, H.; Gifford, E. ADMET in silico modelling: towards prediction paradise? Nat. Rev. Drug Discov., 2003, 2(3), 192-204.
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, Issue.3
, pp. 192-204
-
-
van de Waterbeemd, H.1
Gifford, E.2
-
39
-
-
27144435943
-
In silico predictions of blood-brain barrier penetration: Considerations to keep in mind
-
Goodwin, J. T.; Clark, D. E. In silico predictions of blood-brain barrier penetration: considerations to keep in mind. J. Pharmacol. Exp. Ther., 2005, 315(2), 477-483.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.315
, Issue.2
, pp. 477-483
-
-
Goodwin, J.T.1
Clark, D.E.2
-
40
-
-
18944373550
-
In silico strategies for modeling membrane transporter function
-
Chang, C.; Ray, A.; Swaan, P. In silico strategies for modeling membrane transporter function. Drug Discov. Today, 2005, 10(9), 663-671.
-
(2005)
Drug Discov. Today
, vol.10
, Issue.9
, pp. 663-671
-
-
Chang, C.1
Ray, A.2
Swaan, P.3
-
41
-
-
33644843831
-
Computational approaches to modeling drug transporters
-
Chang, C.; Swaan, P. W. Computational approaches to modeling drug transporters. Eur. J. Pharm. Sci., 2006, 27(5), 411-424.
-
(2006)
Eur. J. Pharm. Sci
, vol.27
, Issue.5
, pp. 411-424
-
-
Chang, C.1
Swaan, P.W.2
-
42
-
-
2442570755
-
Molecular modeling studies on the active binding site of the blood-brain barrier choline transporter
-
Geldenhuys, W. J.; Lockman, P. R.; McAfee, J. H.; Fitzpatrick, K. T.; van der Schyf, C. J.; Allen, D. D. Molecular modeling studies on the active binding site of the blood-brain barrier choline transporter. Bioorg. Med. Chem. Lett., 2004, 14(12), 3085-3092.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, Issue.12
, pp. 3085-3092
-
-
Geldenhuys, W.J.1
Lockman, P.R.2
McAfee, J.H.3
Fitzpatrick, K.T.4
van der Schyf, C.J.5
Allen, D.D.6
-
43
-
-
79952803470
-
How to generate reliable and predictive CoMFA models
-
Zhang, L.; Tsai, K. C.; Du, L.; Fang, H.; Li, M.; Xu, W. How to generate reliable and predictive CoMFA models. Curr. Med. Chem., 2011, 18(6), 923-930.
-
(2011)
Curr. Med. Chem
, vol.18
, Issue.6
, pp. 923-930
-
-
Zhang, L.1
Tsai, K.C.2
Du, L.3
Fang, H.4
Li, M.5
Xu, W.6
-
44
-
-
23244449089
-
Inhibition of choline uptake by N-cyclohexylcholine, a high affinity ligand for the choline transporter at the blood-brain barrier
-
Geldenhuys, W. J.; Lockman, P. R.; Philip, A. E.; McAfee, J. H.; Miller, B. L.; McCurdy, C. R.; Allen, D. D. Inhibition of choline uptake by N-cyclohexylcholine, a high affinity ligand for the choline transporter at the blood-brain barrier. J. Drug Target, 2005, 13(4), 259-266.
-
(2005)
J. Drug Target
, vol.13
, Issue.4
, pp. 259-266
-
-
Geldenhuys, W.J.1
Lockman, P.R.2
Philip, A.E.3
McAfee, J.H.4
Miller, B.L.5
McCurdy, C.R.6
Allen, D.D.7
-
45
-
-
20344387212
-
3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the bloodbrain barrier choline transporter
-
Geldenhuys, W. J.; Lockman, P. R.; Nguyen, T. H.; van der Schyf, C. J.; Crooks, P. A.; Dwoskin, L. P.; Allen, D. D. 3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the bloodbrain barrier choline transporter. Bioorg. Med. Chem., 2005, 13(13), 4253-4261.
-
(2005)
Bioorg. Med. Chem
, vol.13
, Issue.13
, pp. 4253-4261
-
-
Geldenhuys, W.J.1
Lockman, P.R.2
Nguyen, T.H.3
van der Schyf, C.J.4
Crooks, P.A.5
Dwoskin, L.P.6
Allen, D.D.7
-
46
-
-
74049099836
-
Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter
-
Geldenhuys, W. J.; Manda, V. K.; Mittapalli, R. K.; Van der Schyf, C. J.; Crooks, P. A.; Dwoskin, L. P.; Allen, D. D.; Lockman, P. R. Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter. Bioorg. Med. Chem. Lett., 2010, 20(3), 870-877.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, Issue.3
, pp. 870-877
-
-
Geldenhuys, W.J.1
Manda, V.K.2
Mittapalli, R.K.3
van der Schyf, C.J.4
Crooks, P.A.5
Dwoskin, L.P.6
Allen, D.D.7
Lockman, P.R.8
|