Net endogenous acid production is associated with a faster decline in GFR in African Americans

Kidney International

Volumn 82, Issue 1, 2012, Pages 106-112

  Scialla, Julia J ^a   Appel, Lawrence J ^b,c,d   Astor, Brad C ^d,e   Miller III, Edgar R ^b,c,d   Beddhu, Srinivasan ^f   Woodward, Mark ^c,d,g   Parekh, Rulan S ^b,c,h   Anderson, Cheryl A M ^c,d  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^f UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^g GEORGE INSTITUTE FOR GLOBAL HEALTH   (Australia)

^h UNIVERSITY OF TORONTO   (Canada)

Author keywords

AASK (African American Study of Kidney Disease and Hypertension); acidosis; chronic kidney disease; nutrition

Indexed keywords

AMLODIPINE; CREATININE; IOTALAMIC ACID I 125; METOPROLOL; NITROGEN; POTASSIUM; RAMIPRIL; UREA;

ADULT; AFRICAN AMERICAN; AGE DISTRIBUTION; ARTICLE; BODY MASS; COHORT ANALYSIS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSIVE NEPHROSCLEROSIS; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; MULTICENTER STUDY (TOPIC); NEPHROSCLEROSIS; NET ENDOGENOUS ACID PRODUCTION; POTASSIUM EXCRETION; POTASSIUM INTAKE; PRIORITY JOURNAL; PROTEIN INTAKE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RENAL SYSTEM PARAMETERS; RISK FACTOR; UREA NITROGEN BLOOD LEVEL; URINE PROTEIN TO CREATININE RATIO;

EID: 84862493248     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2012.82     Document Type: Article

References (32)

1. Coresh J, Selvin E, Stevens LA et al. Prevalence of chronic kidney disease in the United States. JAMA 2007; 298: 2038-2047. (Pubitemid 350074801)
2. van der Velde M, Matsushita K, Coresh J et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. Kidney Int 2011; 79: 1341-1352.
3. Raphael KL, Wei G, Baird BC et al. Higher serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans. Kidney Int 2010; 79: 356-362.
4. de Brito-Ashurst I, Varagunam M, Raftery MJ et al. Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol 2009; 20: 2075-2084.
5. Shah SN, Abramowitz M, Hostetter TH et al. Serum bicarbonate levels and the progression of kidney disease: a cohort study. Am J Kidney Dis 2009; 54: 270-277.
6. Dorhout-Mees EJ, Machado M, Slatopolsky E et al. The functional adaptation of the diseased kidney: III. Ammonium excretion. J Clin Invest 1966; 45: 289-296.
7. Goodman AD, Lemann Jr J, Lennon EJ et al. Production, excretion and net balance of fixed acid in patients with renal acidosis. J Clin Invest 1965; 44: 495-506.
8. Nath KA, Hostetter MK, Hostetter TH. Pathophysiology of chronic tubulointerstitial disease in rats: interactions of dietary acid load, ammonia, and complement component-C3. J Clin Invest 1985; 76: 667-675. (Pubitemid 15023121)
9. Phisitkul S, Hacker C, Simoni J et al. Dietary protein causes a decline in the glomerular filtration rate of the remnant kidney mediated by metabolic acidosis and endothelin receptors. Kidney Int 2008; 73: 192-199.
10. Mahajan A, Simoni J, Sheather SJ et al. Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy. Kidney Int 2010; 78: 303-309.
11. Frassetto LA, Lanham-New SA, Macdonald HM et al. Standardizing terminology for estimating the diet-dependent net acid load to the metabolic system. J Nutr 2007; 137: 1491-1492. (Pubitemid 46855491)
12. Frassetto LA, Todd KM, Morris Jr RC et al. Estimation of net endogenous noncarbonic acid production in humans from diet potassium and protein contents. Am J Clin Nutr 1998; 68: 576-583. (Pubitemid 28402379)
13. Scialla JJ, Appel LJ, Astor BC et al. Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease. Clin J Am Soc Nephrol 2011; 6: 1526-1532.
14. Zhang L, Curhan GC, Forman JP. Diet-dependent net acid load and risk of incident hypertension in United States women. Hypertension 2009; 54: 751-755.
15. Eknoyan G, Levin A, Levin NW. Bone metabolism and disease in chronic kidney disease. Am J Kidney Dis 2003; 42: 1-201.
16. Wesson DE, Simoni J. Increased tissue acid mediates a progressive decline in the glomerular filtration rate of animals with reduced nephron mass. Kidney Int 2009; 75: 929-935.
17. Wesson DE, Simoni J. Acid retention during kidney failure induces endothelin and aldosterone production which lead to progressive GFR decline, a situation ameliorated by alkali diet. Kidney Int 2010; 78: 1128-1135.
18. Wesson DE, Simoni J, Broglio K et al. Acid retention accompanies reduced GFR in humans and increases plasma levels of endothelin and aldosterone. Am J Physiol Renal Physiol 2011; 300: F830-F837.
19. Phisitkul S, Khanna A, Simoni J et al. Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR. Kidney Int 2010; 77: 617-623.
20. Astor BC, Hallan SI, Miller III ER et al. Glomerular filtration rate, albuminuria, and risk of cardiovascular and all-cause mortality in the US population. Am J Epidemiol 2008; 167: 1226-1234. (Pubitemid 351670638)
21. KDOQI. KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease. Am J Kidney Dis 2007; 49: S12-S154.
22. Agodoa LY, Appel L, Bakris GL et al. Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial. JAMA 2001; 285: 2719-2728. (Pubitemid 32525368)
23. Appel LJ, Middleton J, Miller III ER et al. The rationale and design of the AASK cohort study. J Am Soc Nephrol 2003; 14: S166-S172. (Pubitemid 36750513)
24. Sika M, Lewis J, Douglas J et al. Baseline characteristics of participants in the African American Study of Kidney Disease and Hypertension (AASK) Clinical Trial and Cohort Study. Am J Kidney Dis 2007; 50: 78-89 .e71.
25. Pak CY, Odvina CV, Pearle MS et al. Effect of dietary modification on urinary stone risk factors. Kidney Int 2005; 68: 2264-2273. (Pubitemid 43117803)
26. Robinson J, Lupkiewicz S, Palenik L et al. Determination of ideal body weight for drug dosage calculations. Am J Hosp Pharm 1983; 40: 1016-1019. (Pubitemid 13095552)
27. Maroni BJ, Steinman TI, Mitch WE. A method for estimating nitrogen intake of patients with chronic renal failure. Kidney Int 1985; 27: 58-65. (Pubitemid 15130686)
28. Bingham SA, Gill C, Welch A et al. Validation of dietary assessment methods in the UK arm of EPIC using weighed records, and 24-h urinary nitrogen and potassium and serum vitamin C and carotenoids as biomarkers. Int J Epidemiol 1997; 26: S137.
29. Lewis J, Agodoa L, Cheek D et al. Comparison of cross-sectional renal function measurements in African Americans with hypertensive nephrosclerosis and of primary formulas to estimate glomerular filtration rate. Am J Kidney Dis 2001; 38: 744-753.
30. Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 1999; 94: 496-509.
31. Appel LJ, Wright JT, Greene T et al. Intensive blood-pressure control in hypertensive chronic kidney disease. N Engl J Med 2010; 363: 918-929.
32. Appel LJ, Wright Jr JT, Greene T et al. Long-term effects of renin-angiotensin system-blocking therapy and a low blood pressure goal on progression of hypertensive chronic kidney disease in African Americans. Arch Intern Med 2008; 168: 832-839. (Pubitemid 351620085)