Human umbilical cord blood-derived CD34+ cells reverse osteoporosis in NOD/SCID mice by altering osteoblastic and osteoclastic activities

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Aggarwal, Reeva ^a   Lu, Jingwei ^a   Kanji, Suman ^a   Joseph, Matthew ^a   Das, Manjusri ^a   Noble, Garrett J ^b   McMichael, Brooke K ^c   Agarwal, Sudha ^d   Hart, Richard T ^b   Sun, Zongyang ^d   Lee, Beth S ^c   Rosol, Thomas J ^d   Jackson, Rebecca ^c   Mao, Hai Quan ^e   Pompili, Vincent J ^a   Das, Hiranmoy ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b The Ohio State University   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e Whiting School of Engineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOCALCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE STRUCTURE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL TRANSPLANTATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOPOROSIS; PROTEIN BLOOD LEVEL; THERAPY EFFECT; UMBILICAL CORD BLOOD;

ANIMALS; ANTIGENS, CD34; BONE AND BONES; BONE MARROW; CALCIFICATION, PHYSIOLOGIC; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; OSTEOBLASTS; OSTEOCALCIN; OSTEOCLASTS; OSTEOGENESIS; OSTEOPOROSIS;

EID: 84862492483     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039365     Document Type: Article

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