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Volumn 17, Issue 2, 2012, Pages 174-186

p66Shc-dependent apoptosis requires Lck and CamKII activity

Author keywords

Apoptosis; Lck; p66Shc; T lymphocyte

Indexed keywords

CALCIMYCIN; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; P66SHC PROTEIN; PROTEIN KINASE LCK; PROTEIN SHC; SERINE; UNCLASSIFIED DRUG;

EID: 84862490398     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0663-4     Document Type: Article
Times cited : (9)

References (44)
  • 1
    • 70350426551 scopus 로고    scopus 로고
    • Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters
    • Finetti F, Savino MT, Baldari CT (2009) Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters. Immunol Rev 232(1):115-134
    • (2009) Immunol Rev , vol.232 , Issue.1 , pp. 115-134
    • Finetti, F.1    Savino, M.T.2    Baldari, C.T.3
  • 2
    • 0037151066 scopus 로고    scopus 로고
    • The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter
    • DOI 10.1074/jbc.M200280200
    • Ventura A, Luzi L, Pacini S, Baldari CT, Pelicci PG (2002) The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. J Biol Chem 277(25):22370-22376 (Pubitemid 34967205)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.25 , pp. 22370-22376
    • Ventura, A.1    Luzi, L.2    Pacini, S.3    Baldari, C.T.4    Pelicci, P.G.5
  • 5
    • 17644391695 scopus 로고    scopus 로고
    • p66SHC: The apoptotic side of Shc
    • DOI 10.1007/s10495-005-6057-8
    • Pellegrini M, Pacini S, Baldari CT (2005) p66SHC: the apoptotic side of Shc proteins. Apoptosis 10(1):13-18 (Pubitemid 40558111)
    • (2005) Apoptosis , vol.10 , Issue.1 , pp. 13-18
    • Pellegrini, M.1    Pacini, S.2    Baldari, C.T.3
  • 6
    • 0037192473 scopus 로고    scopus 로고
    • Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
    • DOI 10.1126/science.1069004
    • Nemoto S, Finkel T (2002) Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 295(5564):2450-2452 (Pubitemid 34270258)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2450-2452
    • Nemoto, S.1    Finkel, T.2
  • 11
    • 0037448690 scopus 로고    scopus 로고
    • The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways
    • DOI 10.1038/sj.onc.1206103
    • Belka C, Gruber C, Jendrossek V, Wesselborg S, Budach W (2003) The tyrosine kinase Lck is involved in regulation of mitochondrial apoptosis pathways. Oncogene 22(2):176-185 (Pubitemid 36174175)
    • (2003) Oncogene , vol.22 , Issue.2 , pp. 176-185
    • Belka, C.1    Gruber, C.2    Jendrossek, V.3    Wesselborg, S.4    Budach, W.5
  • 12
    • 0034607647 scopus 로고    scopus 로고
    • Protein tyrosine kinase p56(lck) is required for ceramide-induced but not tumor necrosis factor-induced activation of NF-kappa B, AP-1, JNK, and apoptosis
    • DOI 10.1074/jbc.275.18.13297
    • Manna SK, Sah NK, Aggarwal BB (2000) Protein tyrosine kinase p56lck is required for ceramide-induced but not tumor necrosis factor-induced activation of NF-kappa B, AP-1, JNK, and apoptosis. J Biol Chem 275(18):13297-13306 (Pubitemid 30257386)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.18 , pp. 13297-13306
    • Manna, S.K.1    Sah, N.K.2    Aggarwal, B.B.3
  • 13
    • 42249087767 scopus 로고    scopus 로고
    • Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death
    • Kim MJ, Park MT, Yoon CH, Byun JY, Lee SJ (2008) Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death. Biochem Biophys Res Commun 370(2):353-358
    • (2008) Biochem Biophys Res Commun , vol.370 , Issue.2 , pp. 353-358
    • Kim, M.J.1    Park, M.T.2    Yoon, C.H.3    Byun, J.Y.4    Lee, S.J.5
  • 14
    • 33749247232 scopus 로고    scopus 로고
    • Acid sphingomyelinase mediated release of ceramide is essential to trigger the mitochondrial pathway of apoptosis by galectin-1
    • DOI 10.1016/j.cellsig.2006.02.007, PII S0898656806000416
    • Ion G, Fajka-Boja R, Kovacs F, Szebeni G, Gombos I, Czibula A, Matko J, Monostori E (2006) Acid sphingomyelinase mediated release of ceramide is essential to trigger the mitochondrial pathway of apoptosis by galectin-1. Cell Signal 18(11):1887-1896 (Pubitemid 44485979)
    • (2006) Cellular Signalling , vol.18 , Issue.11 , pp. 1887-1896
    • Ion, G.1    Fajka-Boja, R.2    Kovacs, F.3    Szebeni, G.4    Gombos, I.5    Czibula, A.6    Matko, J.7    Monostori, E.8
  • 15
    • 0346734197 scopus 로고    scopus 로고
    • lck-Dependent Apoptosis in Jurkat and Peripheral T Cells via Mitochondrial Pathway Independent from Fas/Fas Ligand Interaction
    • Hur YG, Yun Y, Won J (2004) Rosmarinic acid induces p56lck-dependent apoptosis in Jurkat and peripheral T cells via mitochondrial pathway independent from Fas/Fas ligand interaction. J Immunol 172(1):79-87 (Pubitemid 38020458)
    • (2004) Journal of Immunology , vol.172 , Issue.1 , pp. 79-87
    • Hur, Y.-G.1    Yun, Y.2    Won, J.3
  • 16
    • 2342577528 scopus 로고    scopus 로고
    • Involvement of tyrosine kinase p56/Lck in apoptosis induction by anticancer drugs
    • DOI 10.1016/j.bcp.2004.01.026, PII S000629520400108X
    • Gruber C, Henkel M, Budach W, Belka C, Jendrossek V (2004) Involvement of tyrosine kinase p56/Lck in apoptosis induction by anticancer drugs. Biochem Pharmacol 67(10):1859-1872 (Pubitemid 38591375)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.10 , pp. 1859-1872
    • Gruber, C.1    Henkel, M.2    Budach, W.3    Belka, C.4    Jendrossek, V.5
  • 17
    • 0029838226 scopus 로고    scopus 로고
    • BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells
    • Uckun FM, Waddick KG, Mahajan S, Jun X, Takata M, Bolen J, Kurosaki T (1996) BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells. Science 273(5278):1096-1100 (Pubitemid 26278163)
    • (1996) Science , vol.273 , Issue.5278 , pp. 1096-1100
    • Uckun, F.M.1    Waddick, K.G.2    Mahajan, S.3    Jun, X.4    Takata, M.5    Bolen, J.6    Kurosaki, T.7
  • 18
    • 0030750736 scopus 로고    scopus 로고
    • Distinctive functions of Syk and Lyn in mediating osmotic stress- and ultraviolet C irradiation-induced apoptosis in chicken B cells
    • DOI 10.1074/jbc.272.29.17994
    • Qin S, Minami Y, Kurosaki T, Yamamura H (1997) Distinctive functions of Syk and Lyn in mediating osmotic stress- and ultraviolet C irradiation-induced apoptosis in chicken B cells. J Biol Chem 272(29):17994-17999 (Pubitemid 27306377)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.29 , pp. 17994-17999
    • Qin, S.1    Minami, Y.2    Kurosaki, T.3    Yamamura, H.4
  • 19
    • 0037097772 scopus 로고    scopus 로고
    • CD4-Lck through TCR and in the absence of Vav exchange factor induces Bax increase and mitochondrial damage
    • Tuosto L, Marinari B, Piccolella E (2002) CD4-Lck through TCR and in the absence of Vav exchange factor induces Bax increase and mitochondrial damage. J Immunol 168(12):6106-6112 (Pubitemid 34620027)
    • (2002) Journal of Immunology , vol.168 , Issue.12 , pp. 6106-6112
    • Tuosto, L.1    Marinari, B.2    Piccolella, E.3
  • 21
    • 30544443793 scopus 로고    scopus 로고
    • The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression
    • DOI 10.1038/sj.onc.1209034, PII 1209034
    • Samraj AK, Stroh C, Fischer U, Schulze-Osthoff K (2006) The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression. Oncogene 25(2):186-197 (Pubitemid 43083680)
    • (2006) Oncogene , vol.25 , Issue.2 , pp. 186-197
    • Samraj, A.K.1    Stroh, C.2    Fischer, U.3    Schulze-Osthoff, K.4
  • 22
    • 34250725402 scopus 로고    scopus 로고
    • 2+ as a key regulator of cell life and death
    • DOI 10.1038/sj.cdd.4402147, PII 4402147
    • Giacomello M, Drago I, Pizzo P, Pozzan T (2007) Mitochondrial Ca2+ as a key regulator of cell life and death. Cell Death Differ 14(7):1267-1274 (Pubitemid 46965258)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.7 , pp. 1267-1274
    • Giacomello, M.1    Drago, I.2    Pizzo, P.3    Pozzan, T.4
  • 23
    • 70349115551 scopus 로고    scopus 로고
    • Regulation of T-cell tolerance by calcium/NFAT signaling
    • Baine I, Abe BT, Macian F (2009) Regulation of T-cell tolerance by calcium/NFAT signaling. Immunol Rev 231(1):225-240
    • (2009) Immunol Rev , vol.231 , Issue.1 , pp. 225-240
    • Baine, I.1    Abe, B.T.2    Macian, F.3
  • 24
    • 70349150893 scopus 로고    scopus 로고
    • Calcium signaling in the development and function of T-lineage cells
    • Oh-hora M (2009) Calcium signaling in the development and function of T-lineage cells. Immunol Rev 231(1):210-224
    • (2009) Immunol Rev , vol.231 , Issue.1 , pp. 210-224
    • Oh-hora, M.1
  • 25
    • 34249824878 scopus 로고    scopus 로고
    • Plasma membrane ion channels in suicidal cell death
    • DOI 10.1016/j.abb.2006.12.028, PII S0003986107000021, Highlight Issue: Pro- and antiapoptotic Signalling
    • Lang F, Huber SM, Szabo I, Gulbins E (2007) Plasma membrane ion channels in suicidal cell death. Arch Biochem Biophys 462(2):189-194 (Pubitemid 46856316)
    • (2007) Archives of Biochemistry and Biophysics , vol.462 , Issue.2 , pp. 189-194
    • Lang, F.1    Huber, S.M.2    Szabo, I.3    Gulbins, E.4
  • 26
    • 56249145090 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: Novel routes for an ancient traveller
    • Racioppi L, Means AR (2008) Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller. Trends Immunol 29(12):600-607
    • (2008) Trends Immunol , vol.29 , Issue.12 , pp. 600-607
    • Racioppi, L.1    Means, A.R.2
  • 27
    • 23244468133 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase IIgammaB impairs positive selection of T cells by modulating TCR signaling
    • McGargill MA, Sharp LL, Bui JD, Hedrick SM, Calbo S (2005) Active Ca2+/calmodulin-dependent protein kinase II gamma B impairs positive selection of T cells by modulating TCR signaling. J Immunol 175(2):656-664 (Pubitemid 41094945)
    • (2005) Journal of Immunology , vol.175 , Issue.2 , pp. 656-664
    • McGargill, M.A.1    Sharp, L.L.2    Bui, J.D.3    Hedrick, S.M.4    Calbo, S.5
  • 28
    • 0029417338 scopus 로고
    • Activation of Ca2+/calmodulin-dependent protein kinase (CaM-kinase) IV by CaM-kinase kinase in Jurkat T lymphocytes
    • Park IK, Soderling TR (1995) Activation of Ca2+/calmodulin-dependent protein kinase (CaM-kinase) IV by CaM-kinase kinase in Jurkat T lymphocytes. J Biol Chem 270(51):30464-30469
    • (1995) J Biol Chem , vol.270 , Issue.51 , pp. 30464-30469
    • Park, I.K.1    Soderling, T.R.2
  • 29
    • 0028076765 scopus 로고
    • Interleukin-2 transcriptional block by multifunctional Ca2+/calmodulin kinase
    • Nghiem P, Ollick T, Gardner P, Schulman H (1994) Interleukin-2 transcriptional block by multifunctional Ca2+/calmodulin kinase. Nature 371(6495):347-350
    • (1994) Nature , vol.371 , Issue.6495 , pp. 347-350
    • Nghiem, P.1    Ollick, T.2    Gardner, P.3    Schulman, H.4
  • 30
    • 0033532583 scopus 로고    scopus 로고
    • Calcium-induced p56(Lck) phosphorylation in human T lymphocytes via calmodulin dependent kinase
    • DOI 10.1006/bbrc.1999.0778
    • Franklin RA, McLeod A, Robinson PJ (1999) Calcium-induced p56(Lck) phosphorylation in human T lymphocytes via calmodulin dependent kinase. Biochem Biophys Res Commun 259(2):283-286 (Pubitemid 29281222)
    • (1999) Biochemical and Biophysical Research Communications , vol.259 , Issue.2 , pp. 283-286
    • Franklin, R.A.1    Mcleod, A.2    Robinson, P.J.3
  • 31
    • 0034491933 scopus 로고    scopus 로고
    • Lck and CaM-kinase
    • DOI 10.1016/S0161-5890(00)00087-0, PII S0161589000000870
    • Franklin RA, Atherfold PA, McCubrey JA (2000) Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase. Mol Immunol 37(11):675-683 (Pubitemid 32112655)
    • (2000) Molecular Immunology , vol.37 , Issue.11 , pp. 675-683
    • Franklin, R.A.1    Atherfold, P.A.2    McCubrey, J.A.3
  • 32
    • 14944380553 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling
    • DOI 10.1182/blood-2004-04-1299
    • Paccani SR, Patrussi L, Ulivieri C, Masferrer JL, D'Elios MM, Baldari CT (2005) Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling. Blood 105(5):2042-2048 (Pubitemid 40731790)
    • (2005) Blood , vol.105 , Issue.5 , pp. 2042-2048
    • Paccani, S.R.1    Patrussi, L.2    Ulivieri, C.3    Masferrer, J.L.4    D'Elios, M.M.5    Baldari, C.T.6
  • 33
    • 0026705903 scopus 로고
    • Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
    • Straus DB, Weiss A (1992) Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70(4):585-593
    • (1992) Cell , vol.70 , Issue.4 , pp. 585-593
    • Straus, D.B.1    Weiss, A.2
  • 34
    • 0242551451 scopus 로고    scopus 로고
    • Early events in Bcl-2-enhanced apoptosis
    • DOI 10.1023/A:1026135509274
    • Liang Y, Yan C, Nylander KD, Schor NF (2003) Early events in Bcl-2-enhanced apoptosis. Apoptosis 8(6):609-616 (Pubitemid 37411745)
    • (2003) Apoptosis , vol.8 , Issue.6 , pp. 609-616
    • Liang, Y.1    Yan, C.2    Nylander, K.D.3    Schor, N.F.4
  • 35
    • 0027467796 scopus 로고
    • A dominant-negative transgene defines a role for p56(lck) in thymopoiesis
    • Levin SD, Anderson SJ, Forbush KA, Perlmutter RM (1993) A dominant-negative transgene defines a role for p56lck in thymopoiesis. EMBO J 12(4):1671-1680 (Pubitemid 23112822)
    • (1993) EMBO Journal , vol.12 , Issue.4 , pp. 1671-1680
    • Levin, S.D.1    Anderson, S.J.2    Forbush, K.A.3    Perlmutter, R.M.4
  • 37
    • 77950655773 scopus 로고    scopus 로고
    • The Bcl-2 family as a rational target for the treatment of B-cell chronic lymphocytic leukaemia
    • Capitani N, Baldari CT (2010) The Bcl-2 family as a rational target for the treatment of B-cell chronic lymphocytic leukaemia. Curr Med Chem 17(9):801-811
    • (2010) Curr Med Chem , vol.17 , Issue.9 , pp. 801-811
    • Capitani, N.1    Baldari, C.T.2
  • 38
    • 32044471627 scopus 로고    scopus 로고
    • 2+-dependent transcriptional induction of Bim of cell death
    • Cante-Barrett K, Gallo EM, Winslow MM, Crabtree GR (2006) Thymocyte negative selection is mediated by protein kinase C- and Ca2+-dependent transcriptional induction of bim [corrected]. J Immunol 176(4):2299-2306 (Pubitemid 43201677)
    • (2006) Journal of Immunology , vol.176 , Issue.4 , pp. 2299-2306
    • Cante-Barrett, K.1    Gallo, E.M.2    Winslow, M.M.3    Crabtree, G.R.4
  • 39
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: Outer membrane permeabilization and beyond
    • Tait SW, Green DR (2010) Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 11(9):621-632
    • (2010) Nat Rev Mol Cell Biol , vol.11 , Issue.9 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 40
    • 32944462153 scopus 로고    scopus 로고
    • A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation
    • DOI 10.1158/1541-7786.MCR-05-0202
    • Shi M, Cooper JC, Yu CL (2006) A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation. Mol Cancer Res 4(1):39-45 (Pubitemid 43259888)
    • (2006) Molecular Cancer Research , vol.4 , Issue.1 , pp. 39-45
    • Shi, M.1    Cooper, J.C.2    Yu, C.-L.3
  • 41
    • 33645120204 scopus 로고    scopus 로고
    • KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)amino-N-(4- chlorocinn amyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels
    • Rezazadeh S, Claydon TW, Fedida D (2006) KN-93 (2-[N-(2-hydroxyethyl)]-N- (4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinn amyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels. J Pharmacol Exp Ther 317(1):292-299
    • (2006) J Pharmacol Exp Ther , vol.317 , Issue.1 , pp. 292-299
    • Rezazadeh, S.1    Claydon, T.W.2    Fedida, D.3
  • 42
    • 61849128182 scopus 로고    scopus 로고
    • T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
    • Salmond RJ, Filby A, Qureshi I, Caserta S, Zamoyska R (2009) T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance. Immunol Rev 228(1):9-22
    • (2009) Immunol Rev , vol.228 , Issue.1 , pp. 9-22
    • Salmond, R.J.1    Filby, A.2    Qureshi, I.3    Caserta, S.4    Zamoyska, R.5
  • 43
    • 77955069880 scopus 로고    scopus 로고
    • The additional loss of Bak and not the lack of the protein tyrosine kinase p56/Lck in one JCaM1.6 subclone caused pronounced apoptosis resistance in response to stimuli of the intrinsic pathway
    • Rudner J, Mueller AC, Matzner N, Huber SM, Handrick R, Belka C, Jendrossek V (2009) The additional loss of Bak and not the lack of the protein tyrosine kinase p56/Lck in one JCaM1.6 subclone caused pronounced apoptosis resistance in response to stimuli of the intrinsic pathway. Apoptosis 14:711-720
    • (2009) Apoptosis , vol.14 , pp. 711-720
    • Rudner, J.1    Mueller, A.C.2    Matzner, N.3    Huber, S.M.4    Handrick, R.5    Belka, C.6    Jendrossek, V.7
  • 44
    • 0037177854 scopus 로고    scopus 로고
    • Characterization of the in vivo sites of serine phosphorylation on Lck identifying serine 59 as a site of mitotic phosphorylation
    • DOI 10.1074/jbc.M111911200
    • Kesavan KP, Isaacson CC, Ashendel CL, Geahlen RL, Harrison ML (2002) Characterization of the in vivo sites of serine phosphorylation on Lck identifying serine 59 as a site of mitotic phosphorylation. J Biol Chem 277(17):14666-14673 (Pubitemid 34952535)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.17 , pp. 14666-14673
    • Kesavan, K.P.1    Isaacson, C.C.2    Ashendel, C.L.3    Geahlen, R.L.4    Harrison, M.L.5


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