Bar proteins in cancer and blood disorders

International Journal of Biochemistry and Molecular Biology

Volumn 3, Issue 2, 2012, Pages 198-208

  Chen, Yolande ^a   Aardema, Jorie ^a   Misra, Ashish ^b   Corey, Seth J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BAR proteins; Blood; Cancer; GTPases; WASP

Indexed keywords

BIN AMPHIPHYSIN RVS DOMAIN PROTEIN; BIN1 PROTEIN; DOXORUBICIN; F BIN AMPHIPHYSIN RVS DOMAIN PROTEIN; INDOLEAMINE 2,3 DIOXYGENASE; INTERCELLULAR ADHESION MOLECULE 1; INVERSE BIN AMPHIPHYSIN RVS DOMAIN PROTEIN; N BIN AMPHIPHYSIN RVS DOMAIN PROTEIN; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; NITRIC OXIDE SYNTHASE; PROLINE SERINE THREONINE PHOSPHATASE INTERACTING PROTEIN; PROTEIN; PROTEIN KINASE FES; PROTEIN SH2; PROTEIN SH3; PROTEIN TYROSINE KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SCAFFOLD PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ACTIN POLYMERIZATION; ALZHEIMER DISEASE; ARTICLE; AUTOINFLAMMATORY DISEASE; BIOGENESIS; CANCER CELL; CANCER GROWTH; CELL MEMBRANE; CENTRONUCLEAR MYOPATHY; CEREBELLUM HYPOPLASIA; CYTOSKELETON; DIABETES MELLITUS; ENDOCYTOSIS; EPITHELIAL MESENCHYMAL TRANSITION; GILLES DE LA TOURETTE SYNDROME; HUMAN; IMMUNOCOMPETENT CELL; LIVER CARCINOMA; LUNG CARCINOMA; MENTAL DEFICIENCY; PLATELE BIOGENESIS; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; T LYMPHOCYTE ACTIVATION; THROMBOCYTOPENIA; TRANSCRIPTION REGULATION; WISKOTT ALDRICH SYNDROME; X LINKED CONGENITAL THROMBOCYTOPENIA;

EID: 84862489843     PISSN: None     EISSN: 21524114     Source Type: Journal    
DOI: None     Document Type: Article

References (99)

1. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT and Horwitz AR. Cell migration: integrating signals from front to back. Science 2003; 302: 1704-1709.
2. Tran Van Nhieu G, Ben-Ze'ev A and Sansonetti PJ. Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin. EMBO J 1997; 16: 2717-2729.
3. Tran Van Nhieu G, Caron E, Hall A and Sansonetti PJ. IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells. EMBO J 1999; 18: 3249-3262.
4. Bourdet-Sicard R and Tran Van Nhieu G. Actin reorganization by SipA and Salmonella invasion of epithelial cells. Trends Microbiol 1999; 7: 309-310.
5. Hayward RD and Koronakis V. Direct nucleation and bundling of actin by the SipC protein of invasive Salmonella. EMBO J 1999; 18: 4926-4934.
6. Dumenil G, Sansonetti P and Tran Van Nhieu G. Src tyrosine kinase activity down-regulates Rhodependent responses during Shigella entry into epithelial cells and stress fibre formation. J Cell Sci 2000; 113: 71-80.
7. Rajabian T, Gavicherla B, Heisig M, Muller- Altrock S, Goebel W, Gray-Owen SD and Ireton K. The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria. Nat Cell Biol 2009; 11: 1212-1218.
8. Prendergast GC, Muller AJ, Ramalingam A and Chang MY. BAR the door: cancer suppression by amphiphysin-like genes. Biochim Biophys Acta 2009; 1795: 25-36.
9. Otani T, Ichii T, Aono S and Takeichi M. Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells. J Cell Biol 2006; 175: 135-146.
10. Kessels MM and Qualmann B. Syndapins integrate N-WASP in receptor-mediated endocytosis. EMBO J 2002; 21: 6083-6094.
11. Feng Y, Hartig SM, Bechill JE, Blanchard EG, Caudell E and Corey SJ. The Cdc42 interacting protein 4 (CIP4) gene knockout mouse reveals delayed and decreased endocytosis. J Biol Chem 2010; 285: 4348-4354.
12. Razzaq A, Robinson IM, McMahon HT, Skepper JN, Su Y, Zelhof AC, Jackson AP, Gay NJ and O'Kane CJ. Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila. Genes Dev 2001; 15: 2967-2979.
13. Nicot AS, Toussaint A, Tosch V, Kretz C, Wallgren- Pettersson C, Iwarsson E, Kingston H, Garnier JM, Biancalana V, Oldfors A, Mandel JL and Laporte J. Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy. Nat Genet 2007; 39: 1134-1139.
14. Leventis PA, Chow BM, Stewart BA, Iyengar B, Campos AR and Boulianne GL. Drosophila Amphiphysin is a post-synaptic protein required for normal locomotion but not endocytosis. Traffic 2001; 2: 839-850.
15. Dharmalingam E, Haeckel A, Pinyol R, Schwintzer L, Koch D, Kessels MM and Qualmann B. F-BAR proteins of the syndapin family shape the plasma membrane and are crucial for neuromorphogenesis. J Neurosci 2009; 29: 13315-13327.
16. Guerrier S, Coutinho-Budd J, Sassa T, Gresset A, Jordan NV, Chen K, Jin WL, Frost A and Polleux F. The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis. Cell 2009; 138: 990-1004.
17. Wells CD, Fawcett JP, Traweger A, Yamanaka Y, Goudreault M, Elder K, Kulkarni S, Gish G, Virag C, Lim C, Colwill K, Starostine A, Metalnikov P and Pawson T. A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. Cell 2006; 125: 535-548.
18. Pykalainen A, Boczkowska M, Zhao H, Saarikangas J, Rebowski G, Jansen M, Hakanen J, Koskela EV, Peranen J, Vihinen H, Jokitalo E, Salminen M, Ikonen E, Dominguez R and Lappalainen P. Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures. Nat Struct Mol Biol 2011; 18: 902-907.
19. Itoh T, Erdmann KS, Roux A, Habermann B, Werner H and De Camilli P. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and FBAR proteins. Dev Cell 2005; 9: 791-804.
20. Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ and Neri C. Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease. Proc Natl Acad Sci USA 2003; 100: 2712-2717.
21. David C, Solimena M and De Camilli P. Autoimmunity in stiff-Man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161. FEBS Lett 1994; 351: 73-79.
22. Sakamuro D, Elliott KJ, Wechsler-Reya R and Prendergast GC. BIN1 is a novel MYCinteracting protein with features of a tumour suppressor. Nat Genet 1996; 14: 69-77.
23. Peter BJ, Kent HM, Mills IG, Vallis Y, Butler PJ, Evans PR and McMahon HT. BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science 2004; 303: 495-499.
24. Tsujita K, Suetsugu S, Sasaki N, Furutani M, Oikawa T and Takenawa T. Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis. J Cell Biol 2006; 172: 269-279.
25. Qualmann B, Koch D and Kessels MM. Let's go bananas: revisiting the endocytic BAR code. EMBO J 2011; 30: 3501-3515.
26. Taylor MJ, Perrais D and Merrifield CJ. A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis. PLoS Biol 2011; 9: e1000604.
27. Henne WM, Kent HM, Ford MG, Hegde BG, Daumke O, Butler PJ, Mittal R, Langen R, Evans PR and McMahon HT. Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature. Structure 2007; 15: 839-852.
28. Takano K, Toyooka K and Suetsugu S. EFC/FBAR proteins and the N-WASP-WIP complex induce membrane curvature-dependent actin polymerization. EMBO J 2008; 27: 2817-2828.
29. Zhu G, Chen J, Liu J, Brunzelle JS, Huang B, Wakeham N, Terzyan S, Li X, Rao Z, Li G and Zhang XC. Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J 2007; 26: 3484-3493.
30. Frost A, Unger VM and De Camilli P. The BAR domain superfamily: membrane-molding macromolecules. Cell 2009; 137: 191-196.
31. Yarar D, Surka MC, Leonard MC and Schmid SL. SNX9 activities are regulated by multiple phosphoinositides through both PX and BAR domains. Traffic 2008; 9: 133-146.
32. Haslam RJ, Koide HB and Hemmings BA. Pleckstrin domain homology. Nature 1993; 363: 309-310.
33. Musacchio A, Gibson T, Rice P, Thompson J and Saraste M. The PH domain: a common piece in the structural patchwork of signalling proteins. Trends Biochem Sci 1993; 18: 343-348.
34. Ford MG, Mills IG, Peter BJ, Vallis Y, Praefcke GJ, Evans PR and McMahon HT. Curvature of clathrin-coated pits driven by epsin. Nature 2002; 419: 361-366.
35. Gallop JL, Jao CC, Kent HM, Butler PJ, Evans PR, Langen R and McMahon HT. Mechanism of endophilin N-BAR domain-mediated membrane curvature. EMBO J 2006; 25: 2898-2910.
36. McMahon HT and Gallop JL. Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature 2005; 438: 590-596.
37. Masuda M, Takeda S, Sone M, Ohki T, Mori H, Kamioka Y and Mochizuki N. Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms. EMBO J 2006; 25: 2889-2897.
38. Verstreken P, Koh TW, Schulze KL, Zhai RG, Hiesinger PR, Zhou Y, Mehta SQ, Cao Y, Roos J and Bellen HJ. Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Neuron 2003; 40: 733-748.
39. Ismail AM, Padrick SB, Chen B, Umetani J and Rosen MK. The WAVE regulatory complex is inhibited. Nat Struct Mol Biol 2009; 16: 561-563.
40. Miki H, Suetsugu S and Takenawa T. WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J 1998; 17: 6932-6941.
41. Miki H, Yamaguchi H, Suetsugu S and Takenawa T. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. Nature 2000; 408: 732-735.
42. Suetsugu S, Murayama K, Sakamoto A, Hanawa-Suetsugu K, Seto A, Oikawa T, Mishima C, Shirouzu M, Takenawa T and Yokoyama S. The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RACdependent membrane deformation. J Biol Chem 2006; 281: 35347-35358.
43. Lee SH, Kerff F, Chereau D, Ferron F, Klug A and Dominguez R. Structural basis for the actin -binding function of missing-in-metastasis. Structure 2007; 15: 145-155.
44. Lin J, Liu J, Wang Y, Zhu J, Zhou K, Smith N and Zhan X. Differential regulation of cortactin and N-WASP-mediated actin polymerization by missing in metastasis (MIM) protein. Oncogene 2005; 24: 2059-2066.
45. Aspenstrom P. A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton. Curr Biol 1997; 7: 479-487.
46. Shimada A, Niwa H, Tsujita K, Suetsugu S, Nitta K, Hanawa-Suetsugu K, Akasaka R, Nishino Y, Toyama M, Chen L, Liu ZJ, Wang BC, Yamamoto M, Terada T, Miyazawa A, Tanaka A, Sugano S, Shirouzu M, Nagayama K, Takenawa T and Yokoyama S. Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. Cell 2007; 129: 761-772.
47. Kamioka Y, Fukuhara S, Sawa H, Nagashima K, Masuda M, Matsuda M and Mochizuki N. A novel dynamin-associating molecule, forminbinding protein 17, induces tubular membrane invaginations and participates in endocytosis. J Biol Chem 2004; 279: 40091-40099.
48. Bu W, Lim KB, Yu YH, Chou AM, Sudhaharan T and Ahmed S. Cdc42 interaction with N-WASP and Toca-1 regulates membrane tubulation, vesicle formation and vesicle motility: implications for endocytosis. PLoS One 2010; 5: e12153.
49. Bu W, Chou AM, Lim KB, Sudhaharan T and Ahmed S. The Toca-1-N-WASP complex links filopodial formation to endocytosis. J Biol Chem 2009; 284: 11622-11636.
50. Ho HY, Rohatgi R, Lebensohn AM, Le M, Li J, Gygi SP and Kirschner MW. Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Cell 2004; 118: 203-216.
51. Yamada H, Padilla-Parra S, Park SJ, Itoh T, Chaineau M, Monaldi I, Cremona O, Benfenati F, De Camilli P, Coppey-Moisan M, Tramier M, Galli T and Takei K. Dynamic interaction of amphiphysin with N-WASP regulates actin assembly. J Biol Chem 2009; 284: 34244-34256.
52. Bauerfeind R, Takei K and De Camilli P. Amphiphysin I is associated with coated endocytic intermediates and undergoes stimulationdependent dephosphorylation in nerve terminals. J Biol Chem 1997; 272: 30984-30992.
53. Richnau N, Fransson A, Farsad K and Aspenstrom P. RICH-1 has a BIN/Amphiphysin/Rvsp domain responsible for binding to membrane lipids and tubulation of liposomes. Biochem Biophys Res Commun 2004; 320: 1034-1042.
54. Lodhi IJ, Chiang SH, Chang L, Vollenweider D, Watson RT, Inoue M, Pessin JE and Saltiel AR. Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes. Cell Metab 2007; 5: 59-72.
55. Arasada R and Pollard TD. Distinct roles for FBAR proteins Cdc15p and Bzz1p in actin polymerization at sites of endocytosis in fission yeast. Curr Biol 2011; 21: 1450-1459.
56. Fricke R, Gohl C, Dharmalingam E, Grevelhorster A, Zahedi B, Harden N, Kessels M, Qualmann B and Bogdan S. Drosophila Cip4/Toca-1 integrates membrane trafficking and actin dynamics through WASP and SCAR/WAVE. Curr Biol 2009; 19: 1429-1437.
57. Andersson F, Jakobsson J, Low P, Shupliakov O and Brodin L. Perturbation of syndapin/PACSIN impairs synaptic vesicle recycling evoked by intense stimulation. J Neurosci 2008; 28: 3925-3933.
58. Pichot CS, Arvanitis C, Hartig SM, Jensen SA, Bechill J, Marzouk S, Yu J, Frost JA and Corey SJ. Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp. Cancer Res 2010; 70: 8347-8356.
59. Hu J, Mukhopadhyay A, Truesdell P, Chander H, Mukhopadhyay UK, Mak AS and Craig AW. Cdc42-interacting protein 4 is a Src substrate that regulates invadopodia and invasiveness of breast tumors by promoting MT1-MMP endocytosis. J Cell Sci 2011; 124: 1739-1751.
60. Senju Y, Itoh Y, Takano K, Hamada S and Suetsugu S. Essential role of PACSIN2/ syndapin-II in caveolae membrane sculpting. J Cell Sci 2011; 124: 2032-2040.
61. You JJ and Lin-Chao S. Gas7 functions with NWASP to regulate the neurite outgrowth of hippocampal neurons. J Biol Chem 2010; 285: 11652-11666.
62. Pyndiah S, Tanida S, Ahmed KM, Cassimere EK, Choe C and Sakamuro D. c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance. Sci Signal 2011; 4: ra19.
63. Prendergast GC. Immune escape as a fundamental trait of cancer: focus on IDO. Oncogene 2008; 27: 3889-3900.
64. Yamamoto H, Sutoh M, Hatakeyama S, Hashimoto Y, Yoneyama T, Koie T, Saitoh H, Yamaya K, Funyu T, Nakamura T, Ohyama C and Tsuboi S. Requirement for FBP17 in invadopodia formation by invasive bladder tumor cells. J Urol 2011; 185: 1930-1938.
65. Roignot J, Taieb D, Suliman M, Dusetti NJ, Iovanna JL and Soubeyran P. CIP4 is a new ArgBP2 interacting protein that modulates the ArgBP2 mediated control of WAVE1 phosphorylation and cancer cell migration. Cancer Lett 2010; 288: 116-123.
66. Yuan R, Fan S, Achary M, Stewart DM, Goldberg ID and Rosen EM. Altered gene expression pattern in cultured human breast cancer cells treated with hepatocyte growth factor/scatter factor in the setting of DNA damage. Cancer Res 2001; 61: 8022-8031.
67. Hsu CC, Leu YW, Tseng MJ, Lee KD, Kuo TY, Yen JY, Lai YL, Hung YC, Sun WS, Chen CM, Chu PY, Yeh KT, Yan PS, Chang YS, Huang TH and Hsiao SH. Functional characterization of Trip10 in cancer cell growth and survival. J Biomed Sci 2011; 18: 12.
68. Lee YG, Macoska JA, Korenchuk S and Pienta KJ. MIM, a potential metastasis suppressor gene in bladder cancer. Neoplasia 2002; 4: 291-294.
69. Wang Y, Liu J, Smith E, Zhou K, Liao J, Yang GY, Tan M and Zhan X. Downregulation of missing in metastasis gene (MIM) is associated with the progression of bladder transitional carcinomas. Cancer Invest 2007; 25: 79-86.
70. Dombrosky-Ferlan P, Grishin A, Botelho RJ, Sampson M, Wang L, Rudert WA, Grinstein S and Corey SJ. Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup. Blood 2003; 101: 2804-2809.
71. Tsuboi S, Takada H, Hara T, Mochizuki N, Funyu T, Saitoh H, Terayama Y, Yamaya K, Ohyama C, Nonoyama S and Ochs HD. FBP17 Mediates a Common Molecular Step in the Formation of Podosomes and Phagocytic Cups in Macrophages. J Biol Chem 2009; 284: 8548-8556.
72. McPherson VA, Everingham S, Karisch R, Smith JA, Udell CM, Zheng J, Jia Z and Craig AW. Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol 2009; 29: 389-401.
73. Koduru S, Kumar L, Massaad MJ, Ramesh N, Le Bras S, Ozcan E, Oyoshi MK, Kaku M, Fujiwara Y, Kremer L, King S, Fuhlbrigge R, Rodig S, Sage P, Carman C, Alcaide P, Luscinskas FW and Geha RS. Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking. Proc Natl Acad Sci USA 2010; 107: 16252-16256.
74. Badour K, Zhang J, Shi F, McGavin MK, Rampersad V, Hardy LA, Field D and Siminovitch KA. The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. Immunity 2003; 18: 141-154.
75. Wise CA, Gillum JD, Seidman CE, Lindor NM, Veile R, Bashiardes S and Lovett M. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum Mol Genet 2002; 11: 961-969.
76. Grosse J, Chitu V, Marquardt A, Hanke P, Schmittwolf C, Zeitlmann L, Schropp P, Barth B, Yu P, Paffenholz R, Stumm G, Nehls M and Stanley ER. Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease. Blood 2006; 107: 3350-3358.
77. Ferguson PJ, Bing X, Vasef MA, Ochoa LA, Mahgoub A, Waldschmidt TJ, Tygrett LT, Schlueter AJ and El-Shanti H. A missense mutation in pstpip2 is associated with the murine autoinflammatory disorder chronic multifocal osteomyelitis. Bone 2006; 38: 41-47.
78. Chitu V, Ferguson PJ, de Bruijn R, Schlueter AJ, Ochoa LA, Waldschmidt TJ, Yeung YG and Stanley ER. Primed innate immunity leads to autoinflammatory disease in PSTPIP2-deficient cmo mice. Blood 2009; 114: 2497-2505.
79. Aardema J, Whichard Z, Strom T, Rawlings D and Corey SJ. Loss of the WASP-Interacting Protein, CIP4, Results In Murine Thrombocytopenia: Insights Into the Pathophysiology of WASP-Related Thrombocytopenia 52nd ASH Meeting, December 7, 2010, Orlando, FL 2010.
80. Chen Y, Aardema J, Kale S, Awomolo A, Whichard Z, Strom T, Rawlings D and Corey SJ. CIP4- Dependent Defects in Platelet Biogenesis Involve Changes in Membrane Rigidity Independently of WASP 53rd American Society of Hematology Annual Meeting and Exposition, San Diego, CA 2011.
81. Jönsson T, Jurak Begonja A, Kormann J, Merkl B, Pluthero F, Kahr WH, Hartwig JH, Plomann M and Falet H. The F-BAR Protein PACSIN 2 Specifically Coats the Anastomosing Intracellular Membrane Systems of Platelets and Megakaryocytes 53rd American Society of Hematology Annual Meeting and Exposition, San Diego, CA 2011.
82. Italiano JE Jr, Lecine P, Shivdasani RA and Hartwig JH. Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes. J Cell Biol 1999; 147: 1299-1312.
83. Patel-Hett S, Richardson JL, Schulze H, Drabek K, Isaac NA, Hoffmeister K, Shivdasani RA, Bulinski JC, Galjart N, Hartwig JH and Italiano JE Jr. Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. Blood 2008; 111: 4605-4616.
84. Thon JN and Italiano JE. Platelet formation. Semin Hematol 2010; 47: 220-226.
85. Thon JN, Montalvo A, Patel-Hett S, Devine MT, Richardson JL, Ehrlicher A, Larson MK, Hoffmeister K, Hartwig JH and Italiano JE Jr. Cytoskeletal mechanics of proplatelet maturation and platelet release. J Cell Biol 2010; 191: 861-874.
86. Falet H, Marchetti MP, Hoffmeister KM, Massaad MJ, Geha RS and Hartwig JH. Plateletassociated IgAs and impaired GPVI responses in platelets lacking WIP. Blood 2009; 114: 4729-4737.
87. Kuwano R, Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Tsukie T, Toyabe S, Akazawa K, Kanazawa I and Ihara Y. Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease. Hum Mol Genet 2006; 15: 2170-2182.
88. Billuart P, Bienvenu T, Ronce N, des Portes V, Vinet MC, Zemni R, Roest Crollius H, Carrie A, Fauchereau F, Cherry M, Briault S, Hamel B, Fryns JP, Beldjord C, Kahn A, Moraine C and Chelly J. Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation. Nature 1998; 392: 923-926.
89. Tentler D, Gustavsson P, Leisti J, Schueler M, Chelly J, Timonen E, Anneren G, Willard HF and Dahl N. Deletion including the oligophrenin-1 gene associated with enlarged cerebral ventricles, cerebellar hypoplasia, seizures and ataxia. Eur J Hum Genet 1999; 7: 541-548.
90. Endris V, Wogatzky B, Leimer U, Bartsch D, Zatyka M, Latif F, Maher ER, Tariverdian G, Kirsch S, Karch D and Rappold GA. The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation. Proc Natl Acad Sci USA 2002; 99: 11754-11759.
91. Paschou P, Feng Y, Pakstis AJ, Speed WC, De- Mille MM, Kidd JR, Jaghori B, Kurlan R, Pauls DL, Sandor P, Barr CL and Kidd KK. Indications of linkage and association of Gilles de la Tourette syndrome in two independent family samples: 17q25 is a putative susceptibility region. Am J Hum Genet 2004; 75: 545-560.
92. Pietropaolo M, Castano L, Babu S, Buelow R, Kuo YL, Martin S, Martin A, Powers AC, Prochazka M, Naggert J, Leiter EH, Eisenbarth GS. Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes- associated autoantigen. J Clin Invest 1993; 92: 359-371.
93. Spitzenberger F, Pietropaolo S, Verkade P, Habermann B, Lacas-Gervais S, Mziaut H, Pietropaolo M and Solimena M. Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells. J Biol Chem 2003; 278: 26166-26173.
94. Cao M, Xu J, Shen C, Kam C, Huganir RL and Xia J. PICK1-ICA69 heteromeric BAR domain complex regulates synaptic targeting and surface expression of AMPA receptors. J Neurosci 2007; 27: 12945-12956.
95. Casal E, Federici L, Zhang W, Fernandez-Recio J, Priego EM, Miguel RN, DuHadaway JB, Prendergast GC, Luisi BF and Laue ED. The crystal structure of the BAR domain from human Bin1/ amphiphysin II and its implications for molecular recognition. Biochemistry 2006; 45: 12917-12928.
96. Chitu V and Stanley ER. Pombe Cdc15 homology (PCH) proteins: coordinators of membranecytoskeletal interactions. Trends Cell Biol 2007; 17: 145-156.
97. Patel SR, Hartwig JH and Italiano JE Jr. The biogenesis of platelets from megakaryocyte proplatelets. J Clin Invest 2005; 115: 3348-3354.
98. Patel SR, Richardson JL, Schulze H, Kahle E, Galjart N, Drabek K, Shivdasani RA, Hartwig JH and Italiano JE Jr. Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood 2005; 106: 4076-4085.
99. Junt T, Schulze H, Chen Z, Massberg S, Goerge T, Krueger A, Wagner DD, Graf T, Italiano JE Jr, Shivdasani RA and von Andrian UH. Dynamic visualization of thrombopoiesis within bone marrow. Science 2007; 317: 1767-1770.