Drosophila amphiphysin is a post-synaptic protein required for normal locomotion but not endocytosis

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Volumn 2, Issue 11, 2001, Pages 839-850

  Leventis, Peter A ^a,c   Chow, Brenda M ^b,c   Stewart, Bryan A ^a,c   Iyengar, Balaji ^d   Campos, Ana Regina ^d   Boulianne, Gabrielle L ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

Actin; Amphiphysin; Endocytosis; Synaptic vesicle recycling

Indexed keywords

ADAPTOR PROTEIN; AMPHIPHYSIN; CLATHRIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL VACUOLE; CELL VIABILITY; CLINICAL PROTOCOL; CONTROLLED STUDY; DEVELOPMENTAL BIOLOGY; DROSOPHILA; EMBRYO; ENDOCYTOSIS; GENE EXPRESSION; IN VIVO STUDY; LARVA; LOCOMOTION; MORPHOLOGY; MUTANT; NEUROMUSCULAR SYNAPSE; NEUROTRANSMISSION; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; STIMULUS RESPONSE; SYNAPSE VESICLE; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA; ENDOCYTOSIS; IMMUNOHISTOCHEMISTRY; LARVA; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEUROMUSCULAR JUNCTION; SEQUENCE HOMOLOGY, AMINO ACID; SYNAPSES;

EID: 0034761885     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2001.21113.x     Document Type: Article

References (46)

1. Molecular mechanisms in synaptic vesicle endocytosis and recycling
2. The function of dynamin in endocytosis
3. Nucleotide-dependent conformational changes in dynamin: Evidence for a mechanochemical molecular spring
4. Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis
5. A presynaptic inositol-5-phosphatase
6. Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid
7. Amphiphysin, a novel protein associated with synaptic vesicles
8. Identification and characterization of a nerve terminal-enriched amphiphysin isoform
9. BIN1 is a novel Myc-interacting protein with features of a tumour suppressor
10. Inhibition of receptor-mediated endocytosis by the amphiphysin SH3 domain
11. The N terminus of amphiphysin II mediates dimerization and plasma membrane targeting
12. Clathrin interacts specifically with amphiphysin and is displaced by dynamin
13. Role of phosphorylation in regulation of the assembly of endocytic coat complexes
14. Multiple amphiphysin II splice variants display differential clathrin binding: Identification of two distinct clathrin-binding sites
15. A new member of the amphiphysin family connecting endocytosis and signal transduction pathways
16. A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals
17. Synaptic vesicle endocytosis impaired by disruption of dynamin-SH3 domain interactions
18. Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis
19. The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity
20. Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites
21. end5, end6 and end7: Mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae
22. Interaction of yeast Rvs167 and Pho85 cyclin-dependent kinase complexes may link the cell cycle to the actin cytoskeleton
23. Yeast mutant affected for viability upon nutrient starvation, characterization and cloning of the RVS161 gene
24. Alteration of a yeast SH3 protein leads to conditional viability with defects in cytoskeletal and budding patterns
25. Actin cytoskeleton and budding pattern are altered in the yeast rvs161 mutant: The RVS161 protein shares common domains with the brain protein amphiphysin
26. Rvs167p, the budding yeast homolog of amphiphysin, colocalizes with actin patches
27. Amphiphysin binds the cdk5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2
28. Characterization of the gene for Drosophila amphiphysin
29. A genome-wide search for synaptic vesicle cycle proteins in Drosophila
30. A genetic screen to identify components of the sina signaling pathway in Drosophila eye development
31. The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability
32. dgq: A Drosophila gene encoding a visual system-specific G alpha molecule
33. G protein diversity, a distinct class of alpha subunits is present in vertebrates and invertebrates
34. The structural era of endocytosis
35. The tamas gene, identified as a mutation that disrupts larval behavior in Drosophila melanogaster, codes for the mitochondrial DNA polymerase catalytic subunit (DNApol-gamma125)
36. Properties of the larval neuromuscular junction in Drosophila melanogaster
37. Size of vesicle pools, rates of mobilization, and recycling at neuromuscular synapses of a Drosophila mutant, shibire
38. Amphiphysin II (SH3P9;BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle
39. Structural analysis of the BIN1 gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing
40. The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure
41. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
42. Systemic gain-of-function genetics in Drosophila
43. Type I repressors of P element mobility
44. SNARE Proteins contribute to calcium cooperativity of synaptic transmission
45. Variation in GABA mini amplitude is the consequence of variation in transmitter concentration